/r/gutscience

Photograph via snooOG

Tracking the progress of the understanding of our gut microbiome and its relation to health.

Related health issues : IBD, IBS, immune problems, mental health, GERD, bacterial/viral infections.

Since 2010 there has been a great increase in gut microbiome related science publications. Studies show strong links between our gut microbes and various health issues, including immunity, mental health, obesity.


Microbiome - "the ecological community of commensal, symbiotic, and pathogenic microorganisms that literally share our body space." This term was originally coined by Joshua Lederberg, who argued the importance of microorganisms inhabiting the human body in health and disease.

The human body contains over 10 times more microbial cells than human cells, although the entire microbiome only weighs about 200 grams (7.1 oz), with some weight estimates ranging as high as 3 pounds (approximately 48 ounces or 1,400 grams). Some consider it to be a "newly discovered organ" since its existence was not generally recognized until the late 1990s and it is understood to potentially have overwhelming impact on human health.[8] Modern DNA sequencing techniques have enabled researchers to find the majority of these microbes, since the majority of them cannot be cultured in a lab using current techniques.

The human microbiome may be implicated in auto-immune diseases like diabetes, rheumatoid arthritis, muscular dystrophy, multiple sclerosis, fibromyalgia, and perhaps some cancers. Common obesity might also be aggravated by a poor mix of microbes in the gut. Since some of the microbes in our body can modify the production of neurotransmitters known to be found in the brain, we may also find some relief for schizophrenia, depression, bipolar disorder and other neuro-chemical imbalances.

Microbiomes are being characterized in many other environments as well, including soil, seawater and freshwater systems. It is believed that endosymbiosis originally gave rise to more complex organisms, and continued to play a fundamental role in guiding their evolution and expansion into new niches. The microbes being discussed are generally non-pathogenic (do not cause disease unless they grow abnormally); they exist in harmony and symbiotically with their hosts.

Researchers have learned that much of the population of microbes found in the human body are not bacteria but a very old class of single-celled organisms called archaea. Wikipedia: microbiome


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/r/gutscience

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2

Can I (17 F) have my gut surgically removed and still live?

I know it probably sounds daft but the documentary had some terrifying cases of this, including a woman who survived it, it was a woman in her 30's and she said she suddenly felt hot in her throat, and then flames started spewing from her mouth. She drank water and the fire was put out, but she sustained 3rd degree burns to her stomach and intestines and had a scar on her abdomen because of the heat of the fire coming from her gut.

The others weren't so lucky and were found reduced to a pile of ashes. For example there was one where a son was talking to his mother upstairs, then he went downstairs for 15 minutes. He then came back up to find his mother was burned to death in her chair, with her legs and arms and head intact but the stomach area was completely burned out and reduced to ashes.

Ever since that I can't stop thinking my gut will suddenly catch fire. The documentary had a British chemist named John Emsley mention that our guts produce a self-combusting liquid called diphosphane but in tiny amounts, too small to cause self-combustion, but in some cases it can produce too much and this ignites all the other flammable stuff in the gut and can blow a hole through the abdomen in some cases as it's more like a fiery explosion.

Another terrifying fatal case was witnessed by relatives and the woman was just reading a newspaper when suddenly blue flames burst from her mouth and gut area before she died. The documentary had a terrifying reconstruction of this, specifically when her relative looked away for a second and suddenly saw flames in the corner of his eye, only to see her spewing flames out of her mouth and abdomen like a dragon, while she was completely motionless/in shock.

Ever since I can't stop thinking about my gut just bursting into flames and burning to death from it. I always have a glass of water next to me in case it happens, and when I go to sleep I have a 2 L bottle of water next to me. I hate being human sometimes our bodies are so badly designed, I've never heard of birds exploding into flames and there's like a hundred times more birds than people.

Whenever I'm talking with friends I get anxious, thinking they might suddenly start having fire bursting out their mouth and gut, then keel over and burn to death from the inside out, and imagining how traumatised I'd be if that happens. This case is one of the most haunting ones for me - https://enacademic.com/dic.nsf/enwiki/1034226

Is it possible to remove the gut surgically? Ever since I saw this documentary I want to get rid of it because I feel like I have a bomb inside of me.

2 Comments
2020/01/31
12:55 UTC

10

What's the best method of replenishing friendly bacteria after a course of antibiotics?

I've been eating yogurt but it only contains 2 kinds of bacteria. How can I reintroduce diversity into my system?

1 Comment
2019/04/08
09:22 UTC

10

The Power of Poop. Fecal Transplants See Success in 90 Percent of Bacterial Gut Infections.

0 Comments
2019/03/12
01:47 UTC

1

Gallbladder Troubles

Hello,

This is my first time posting about my gut issues. Long story short, I had a "significant" amount of gallstones form after losing ~100 pounds over the course of a year. After nearly a year from this diagnosis (I had two really bad gallbladder attacks that sent me to the ER) I finally was able to have surgery to remove my gallbladder.

My current issue: it is now almost 2 months after my surgery, and while recovery has had its hiccups in the form of weird bowel movements, my main concern is flatulence. Feel free to laugh all you want, but my farts are really otherworldly in how rancid they smell. They are typically the worst after having a meal with relatively high fat content as my condition does not do super well with this yet. I had similar issues just prior to having my surgery as well. I'm wondering if there is anything I can do or take to help relieve this gas? Although my S/O claims she's used to it and cool with me being farty, I would rather not have to have her suffer through it as well as me being embarrassed in public. Thanks for anything you can recommend!

TL;DR: My farts are awful after eating fatty meals following gallbladder removal and I am looking for anything to do/take to relieve this.

0 Comments
2019/03/06
03:48 UTC

1

Gut health, Keto & Aura

Hey guys. I’m trying out keto currently and it seems like my gut really doesn’t like it.

I usually start my mornings with 5g Creatine, multivitamin and omega-3. Then gym. I drink a lot of water. I’ve stopped taking BCAA because it pretty much depletes a lot of my serotonin and makes me pretty low mid day.

Breakfast:

  • Usually eggs (I think this is a trigger)
  • Cheese, Salami, butter
  • Cucumber, Peppers

I’m getting the following symptoms:

  • Growling
  • Burping crazily
  • Brain fog
  • Temporary memory loss (with the brain fog)
  • Aura (Migraine symptoms)
  • Extreme mood swings
  • High blood pressure
  • Feeling tense / pain in my feet
  • Pain in my neck

These symptoms sit there for around 2-3 hours and I’m resurrected, pretty much PTSD after each event thinking “What the fuck was that?”

The only thing that helps is showering and cortisone. I’ve tried 5HTP and it helps a tad. I’m not taking any medication except for my asthma meds - salbutamol. I’d love any advice you can give me please.

8 Comments
2018/10/12
12:45 UTC

2

basically scientific american has 3000 words on a discovery of a new lymph tissue inside the brain, which makes dumb assumptions about neuroinflammation seem dumb

6 pages of the magazine, scanned upside down: https://imgur.com/a/fcbfgp5

Scientific American August 2018
###The Seventh Sense

  • Long thought to be divorced from the brain, the immune system turns out to be intimately involved in its functioning
    • By Jonathan Kipnis

For decades anatomy textbooks taught that the two most complicated systems in the body—the brain and the immune system—existed in almost complete isolation from each other. By all accounts, the brain focused on the business of operating the body, and the immune system focused on defending it. In healthy individuals, the twain never met. Only in certain cases of disease or trauma did cells from the immune system enter the brain, and when they did so, it was to attack.

2 Comments
2018/09/26
18:21 UTC

4

Ayahuasca obliterates gut flora?

I've been interested in ayahuasca but I just realised that the vomiting & diarrhoea that comes with the "purging" might be obliterating the gut flora you have. Is this a necessary "evil" of harmala alkaloids found in ayahuasca vines?

I may reconsider my intentions to consume ayahuasca if it does harm to my body as a supposed trial in a spiritual ceremony.

3 Comments
2018/08/03
01:43 UTC

2

Two quick questions

I’ve read that if there isn’t enough prebiotic fiber in your diet the probiotics in your gut will begin to feed on your mucus lining.

My first question, and please forgive my ignorance here but... when the “mucus lining of the gut” is mentioned, especially in the aforementioned context, is it referring to the mucus lining of the intestines or the stomach?

My second question: Is it possible for digestive enzymes to render prebiotic fiber inedible to probiotics? Can digestive enzyme supplements be intense enough to have this effect on prebiotic fiber?

0 Comments
2018/06/11
04:35 UTC

2

Fasting & Gut Health

Hi all, any information on implications for gut health during extended fasts, 2 -3 days dry fasting and or 4-5 days water fasts? Thanks in advance

2 Comments
2018/05/20
04:02 UTC

2

Pooping out all the seeds of okra

Do the seeds of okra get broken down in fully functioning gut?

I have noticed some hardy stuff (some protein) come out in my poop undigested, but I am surprised that all the seeds of okra have too.

1 Comment
2018/04/17
14:02 UTC

2

Repairing smooth gut muscle function

Does anyone here have some knowledge on how to fix gut smooth muscle function? I have an issue where my gut gets very loud. No other symptoms/problems, just this. I have talked to doctors but haven't gotten any help since they don't know what the problem might be. I believe it is my gut smooth muscle being hyperactive. I'm thinking of maybe trying glycine and seeing if that helps. Also, herbs/medication with some kind of calcium channel blocking abilities do appear to help but it does not last long.

1 Comment
2018/01/01
21:46 UTC

1

Seeking participants for new study about societal views of IBD - enter a prize draw to win gift cards!

If you are interested in sharing your perspectives on the general public’s views of IBD, then you are welcome to participate in a new and interesting study!

All you have to do is complete a short online questionnaire. It will take about 20-30 minutes and you can enter a prize draw to win one of three $30 Amazon eGift Cards to thank you for your participation.

Individuals with Inflammatory Bowel Disease (types of Crohn’s Disease/Ulcerative Colitis/Indeterminate Colitis) can participate. Volunteers must be between the ages of 18-60 and may be currently in remission or experiencing a relapse/flare.

To participate/find out more, go to: https://griffithbbh.co1.qualtrics.com/SE/?SID=SV_dcyPb81SucasPEF Elia Polak, Griffith University, Australia (GU Ref No: 2016/138)

0 Comments
2017/08/31
01:16 UTC

9

Gut Brain Connection | Does Your Gut Hold the Key to Better Brain Health?

0 Comments
2017/06/14
05:00 UTC

2

New IBD Support Group on Discord, with channel for Microbiome

To join just make a comment or send me a PM and I'll send you a link to join the server!

0 Comments
2017/05/23
18:09 UTC

2

Why Is Gut Flora So Important?

0 Comments
2017/05/15
12:37 UTC

2

Microbiome diet plan available for free from rockridge press

Register for a free advance digital review copy here

More info: Independent publisher of Berkeley, CA is distributing digital review copies of The Microbiome Diet Plan by DANIELLE CAPALINO, MSPH, RD, CDN.

0 Comments
2017/05/10
19:14 UTC

2

Does stevia negatively affect gut health?

I know there is evidence that sugar and artificial sugar substitutes feed the bad bacteria in our stomachs. I haven't found much on stevia. What I have found indicated that it did not have any effect on flora. Is this congruent with your beliefs?

0 Comments
2017/03/23
23:23 UTC

2

Diet modification and ibd research survey

Happy Sunday. I am coming to the end of my journey with my Master's in Clinical Nutrition and am conducting a research study as my capstone project. I was very drawn to this topic due to my personal struggle with IBD. The study focuses on the impact of following a specific diet on quality of life in inflammatory bowel disease adults. I would truly appreciate your participation in my survey or sending the survey to anyone that you think might be interested in participating. Here is the link https://nyu.qualtrics.com/SE/?SID=SV_2nr596Br0m4KY05 Thank you so much for your help!! :)

0 Comments
2017/03/13
03:18 UTC

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