/r/stemcells
Welcome to r/stemcells! The purpose of this subreddit is to highlight exciting research, prospects, experiences, and discussion, as well as to point out the pitfalls and unknowns regarding stem cell therapy.
The Stem Cells Subreddit
r/stemcells is for discussing the latest news on stem cell treatments and research.
NO ADVERTISEMENTS ALLOWED.
Learn more about stem cells:
Stem Cell Basics from the NIH https://stemcells.nih.gov/info/basics/stc-basics
Related sub-reddits
/r/stemcells
Anyone talked to Infinity clinic in Ukraine/Prague and can give details on what a treatment costs and how many cells they give?
I had a thiamine deficiency and i was wondering if swiss medica in europe is legit. I'm very scared to be scammed
Frozen vs Fresh
There are many questions regarding the safety and efficacy of using frozen cells as opposed to fresh cells. The safety of material used to cryopreserve, and the viability of cells that pass sub-zero temperatures during storage and transport are questions that need to be addressed.
Cryopreservation is a means to slow down and bring to a halt, metabolic functions within a living organism and prevent the decomposition of various organic compounds that make up that living organism. This is achieved by safely transitioning the organism into a sub-zero frozen state. The lower the temperature, the firmer the paused life system. Even today, safely achieving this state is no less than a miracle. Modern cryogenic technology allows precise control over temperature and materials to preserve structural integrity. However, the biochemical complexities of specific tissues or cells govern how well they can be preserved in sub-zero temperatures and for how long. Parameters for temperature, pressure, transition timelines, gaseous exposure, light spectrums, and contamination safety measures are specific for different cells or tissue entering or exiting a cryopreserved state (thawing).
Thawing is the process of safely recovering cryopreserved cells where ideally, the cell structural integrity and cell mortality can be minimized during the restoration of the cells back to life. The level of environmental control required to transition between these phases makes handling post-cryopreservation thawing particularly a challenge during human therapeutic rendering. Primary factors impacting the thawing process are inferior clinical environments, clinicians who lack training, understanding, or experience in cell biology, the complete lack of regulatory oversight concerning clinical handling of biologic material meant to be injected into human subjects, the lack of handling precision on the clinical side (sound scientific protocol), the unreliability of measures to ascertain the success of the thaw, as well as the impact from materials used during the cryopreservation process itself.
Bottom line...this is an incredibly complicated process. A stem cell lab is likely to possess the equipment, trained staff and experience to cryopreserve cells but it's really important to find out if the clinic that's providing the treatment possesses what it takes to reactive the cells safely. It's a lot more complicated than just leaving the vials at room temperature for an hour
I had an alcohol addiction for 5 years. I didn't eat and got a thiamine (vitamine b1) deficiency which led me to develop neuropathy, vision issues, memory issues etc... I wonder if stemcell treatment could help for this? I'm only 25 and i don't wanna live in this body tbh
Hi, I'm planning to do stemcells injection, and searching for supplement which could boost cartilage recover. My list now: collagen peptides, collagen type 2, SAMe, boron, glucosamine, chondroitin, prolin , vitamin c . Appreciate for help to increase this list
Not sure if this is the right sub, but I have to get it off my chest. In February of 2023, I was called by be the match due to me being a potential donor and obviously I did it because I feel someone else out there would do it for me. My recipient reached out to me today and thanked me profusely. I really saved their life. I don’t have many friends, so I don’t really have an outlet to express my emotions or share my experience. It is and will be the most rewarding thing I’ve ever done, so please please please if you’re willing and able to join the national bone marrow transplant registry, do it. It’s a surreal feeling to know I’ve had such an impact on someone’s life. Peace and love people, thanks for letting me get it off my chest.
Do you know the best in clinic in the north of the US? I am from canada
Has anyone had cartilage recovery for their joint after an umbilical cord stem cell treatment or treatments? Something you can actually see on an MRI?
If yes,
If no, please let me know as well.
........ Why I ask: 2018 a person hit my car going an excessive speed and totaled it, twisting my ankle and causing necrosis in the joint. Had to have a major surgery. And the ankle has never been the same since. I have done multiple bone marrow stem cell transplants and multiple umbilical cord stem cell transplants. Just looking to find out if anyone has had cartilage repair from umbilical cord stem cells. ........
Thank you for your assistance in advance.
Currently I'm looking into getting a stem cell injections for ankle arthritis. These are autologous mesenchymal stem cells from either adipose tussie or bonemarrow. I'm trying to figure out what is known about potential side effects. So far, the main issues I'm finding are the same as for PRP inejctions, namely infection or injury at the injection site.
Is there anything else known (or yet potentially unknown) with regards to side effects of the actual presence of stem cells?
I’m a 30yo male that injured my hip/lower back in a weightlifting accident 7 years ago. It tore some ligaments and tendons in my SI joint. I refused to get my back fused. According to my latest ct scan, osteoarthritis has set in at my hips because of the injury. Would stem cells help heal the injury? Or help with the arthritis? I’m new to researching stem cells, so any information on the type of stem cells or the best place to get the procedure done is very appreciated. (I’m located in the U.S, so I’m willing to travel)
I have developed pretty bad memory issues after alcohol addiction. Also my vision got pretty bad :/ Is stemcell treatment after alcohol abuse something that gets done? Would it work or isn't it worth the risk?
Has anyone had treatment done to heal damage to the heart? If so, when did you start feeling better and we're the effects long lasting?
Why do people go to other countries for stem cells? Cant you still get treated in the US it's just not FDA approved. Is it an experience or expense thing? Doesn't it make it tough to determine a trustworthy facility/source.
Hey, I have some chronic pain issues with my neck (C6 disk is damaged due to suspected slipped disk from about 15yrs ago, MRI showed the damage, it looked 20 years "older" than it should) and got interested in Stem cell treatments after hearing about it via ways2well.
Can anyone recommend a clinic here in or near to Germany, or is it a must to travel abroad?
Thanks!
There's this paper comparing bone marrow MSC counts vs 5 whartons jelly makers, finding no MSC in the latter.
But it's pretty expensive to buy the paper to read it... is there anybody, maybe student or something who could send me this paper over DM please?
https://pubmed.ncbi.nlm.nih.gov/34398643/
I'd greatly appreciate it, thanks!
Kinda surprised how expensive these places are?
Have you all paid this much? Was it worth it?
Quotes from cpi stem among 2 others.
I have severe Long Covid and recently experienced some improvements with Rapamycin and Abilify. After about a month on these medications, I had an infusion of mesenchymal exosomes. A week or so after the date of infusion, it seems my medications lost their effectiveness as I started to backslide. Has anyone else experienced a similar response to exosomes, or does anyone have any insights as to why medication could lose effectiveness post-infusion? Thanks for any input!
I spoke to various clinics and I'm trying to reverse joint damage from middle age overuse
Essentially I want to be healing better. And fix some nagging problems in back neck shoulder possibly hips.
I do alot of mtn biking and lifting amd swimming and I am getting older
So I wonder what folks experience have been with generic iv drips vs direct joint injection
Some clinics do one and some the other
In doing research to narrow down which provider I want to go to (outside of the US) I find this sub to be not the best. The provider I like appears to be creating shill accounts to pump their business -- I dislike this but they may still be an okay provider. Then on the contrast, I see accounts attacking providers and/or calling out these shill accounts. So reddit is proving to be a pretty unreliable source for testimonials. This is pretty unfortunate given how "overly marketed" (scammy) the stemcell space is already.
My question is this: What thought/process framework do you apply to find a legitimate provider whilst eliminating low integrity/scammer providers?
(Please do not recommend a specific provider)
I have undergone a cervical disc replacement for a herniated disc (C6 - C7) in Dec 2022. There were complications and I had a revision Aug 2023. My recent emg shows that one muscle is no longer affected, but the three others still have nerve damage, albeit some evidence of healing has occurred. However, since it has been going on for over 2 years the doctor doesn't think that there will be much improvement moving forward.
Are there any stem cells options that are worth looking into for my case? Can treatment help improve existing nerve recovery?
I have neurological issues post Covid and the worst ones are tinnitus and burning pain in the face. I get electric shocks and burning. Would love to try regenerative medicine but the information is overwhelming! Every clinic seems to have a different idea or protocol?
I am a recent ALS diagnosis looking at alternative medicines/treatments to throw the kitchen sink at this thing early. I've seen some Exosome IV therapy that wouldn't require going out of country. I was looking to work out a protocol of administering 4-6 maybe 8 treatments once every two weeks or once a month, whatever the doc recommends.
What questions should I ask during consultation?
Should I push for a specific frequency to the treatments?
What quality or quanitity of Exomores should be used?
I would assume it should be umbillical, not marrow derived. Thoughts on any of this?