/r/Microbiome
Welcome to r/Microbiome :)
Please make sure you are using the correct flair if applicable.
The Microbiome Reddit
Microbiome - an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multicellular organisms studied to date from plants to animals. A microbiota includes bacteria, archaea, protists, fungi and viruses. Microbiota have been found to be crucial for immunologic, hormonal and metabolic homeostasis of their host. The synonymous term microbiome describes either the collective genomes of the microorganisms that reside in an environmental niche or the microorganisms themselves.
The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genomic characteristics, sometimes collectively referred to as a holobiont.
Related Reddits
A multi-reddit of the following subs.
Outside Reddit Sites
Fantastic microbiome 101 podcast by Yale. Other parts in the series.
MostlyMicrobes.com - a collection of stories and resources about the microbes that influence our lives.
Wikipedia: Microbiome
Wikipedia: Human Microbiome
Wikipedia: Human Microbiome Project
You can use sci-hub to access paywalled studies.
/r/Microbiome
Hi, guys I made a post a week ago seeking some advice on my stomach issues. I’ve had stomach issues for as long as I can remember. I was just wondering if anyone else gets phlegm and mucus from eating foods? I notice it worse with some foods but I’m constantly hawking up loogies literally right after I swallow something. I was told by a doctor it’s a histamine reaction and I do have bad seasonal allergies but I literally get it when I eat absolutely anything even healthy foods. It’s frustrating and gross and I was wondering if fixing my gut micro biome and maintaining a healthy gut will fix this or if I’ll just have to live with it forever? Thanks guys!
I tried to find information on this, but can’t seem to find much. Any help is appreciated!
I’ve seen many posts here and in the SIBO subreddit advising against probiotics and prebiotics like PHGG, as they can often worsen symptoms. I’m waiting to undergo testing to determine whether my bloating, distension, and constipation are related to the small or large intestine, but I’m trying to figure things out in the meantime.
I’ve noticed that I don’t experience bloating or issues when taking probiotics or prebiotics. Could this indicate that my symptoms might not be related to the small intestine, and perhaps moreso colon dysbiosis?
I quit drinking after regularly drinking for a few years now. I was having inflammation and was so unregular, but beer helped! But, now... I'm constipated, my anus has some kind of either road or fissure or something. So going is uncomfortable. I've been taking beetlax and probiotics. Do I need pro, pre, AND post biotics? What can I do to help my healing journey? My poor gut, no one tells you this can happen, but now that it's happened apparently it's so common , people just don't talk about it. Well, I'm here to say don't wait if your seeing concerning issues. Stop drinking and get it checked out before it's a life long issue. Im learning more and more, but nothing really about helping other than fiber. I have mushroom husks and I'm eating healthy. I'll get activia. Any other suggestions? Do I really need post, pro, and pre biotics?? That's been bugging me. I only take probiotics... now I think I need to up my game. Any help or support appreciated.
Recently my wife and I had a newborn (4months) ago and roughly the same time I started developing all kinds of weird symptoms. Roughly 1 month in, started to develop anxiety that correlated with upset stomach. My whole life, my stomach would get upset before games or social events that made me nervous (butterflies). However, now it seems to be correlated to histamine build up especially in the morning time. I was having vertigo symptoms and my doctor told me that I did have fluid in my ears and post nasal drainage is contributing to the upset stomach in the morning. I was prescribed zyrtec for allergies to dry up my nasal cavities. It's helped dramatically for my stomach issues as well as my anxiety. However, I'm still concerned this is more of a gut issue versus allergy issues as I have never had issues with allergies. I have ringing in my ears from time to time, as well as, dizziness on occasion. I don't take any supplements but do drink 3-4 liters of water and day depending on if it's a running day or not.
Full transparency, i was drinking energy drinks on the daily before stopping 3 months ago, still have not had one sense nor caffeine for that matter.
Today I had minor surgery, and the doctor prescribed cephalexin (500mg 4 times a day). I'm pretty upset about it because I had c-diff 6 years ago after taking clindamycin and I still have IBS. The pharmacist agrees with the surgeon that cephalexin is necessary and it's the best option.
I already take boullardi, l reuteri, and b coagulans. I eat sauerkraut, kimchi, miso, yogurt and kefir but some days I can't eat any of that because my bowels are so cranky. The pharmacist said to take Bio-K, and the health food store lady said to take it 2 hours after the cephalexin.
I would be very grateful for anything you folks can tell me about how to manage the timing of the probiotics, or other steps I can take to protect myself. I'm feeling pretty discouraged right now.
I recently had one and was curious about the effect it would have on my microbiome.
urgent help please because this wording is confusing and i’ve interpreted that i don’t have yeast overgrowth but maybe i do?
Levels are sky high. Only info I can find is connection to MS and I'm concerned considering I have a lot of symptoms ( tinnitus, buzzing legs, numb hands).
I cannot find any information on this why it would be this high. I don't have any food poisoning symptoms
Both tests originally $199
https://shop.biomesight.com/products/gut-microbiome-test-snapshot-sale
Any advice, experience with either test?
Hello, I am working on healing naturally from chronic fatigue as no doctor has been able to help me. I've been taking tons of detox supplements for cellular health, vitamins, minerals, all kind of things and recently weird stuff has been coming out of me. I was wondering could someone help me identify what came out of me through my stool?? DISCLAMER GROSS PICTURE IN COMMENTS
I am currently on day 7 of a 10 day course of Keflex (500 ml x 4 times a day) for an infection in my leg. At the same time I have lost 5-7 pounds. I haven't had vomiting or diahrrea which I know are side effects and have only experienced nausea and stomach upset starting yesterday, day 6 so that wouldnt account for the weight loss. I am concerned about the rapid weight loss For other reasons, I had a ct scan of my abdomen and pelvis four and a half months ago and blood work two and half months ago all normal, so I am wondering if I need to get more testing done?
Hi,
Has anyone had success or benefits with bovine colostrum in terms of healing or helping their leaky gut?
Thanks!
Hi, I bought BioGaia Osfortis. First time I took the pill, I had felt a strong fatigue, so I didn’t continue. Now, after some time, I took the pill again - and the same fatigue reoccured. I had a problem with chronic fatigue, which I’m recovering from. Should I push through and continue taking the probiotic? I’ve tried Symprove probiotic, which also contains l. reuteri (but, unlike BioGaia, it contains less of it plus it contains other strains) and it didn’t cause fatigue.
Hey all
Spent 14 days in hospital for very high infection levels. I was hooked up to antibiotic drips for about 10 days and also took a variety of oral antibiotics. I'm guessing my Microbiome has been nuked.
So should I be taken any probiotics now or should I just rely on eating good food. If food then what types are the best for my gut health now.
Thanks in advance for any help.
So I spent my 20s travelling around the world, drinking a lot, smoking etc. Thankfully, I've only been on antibiotics twice in my life so not sure if that did heaps of damage, but I am sure I picked up many tummy bugs from around the world. I recently finished my master's degree and just starting out with my career, so GI Map and co. are a bit out of budget.
My symptoms include bloating, irregular bowel movements and floating number 2's, frequent tummy pain and gas.
Can I just dive into general gut healing modalities without knowing what I'm up against? IF yes, where do I start?
Hello! I’m new heee by now really new to the gut problems. I’m 16F and currently have Hypothalamic amenorrhea since 2022. That is a whole nother story but yea I tired recovering and this is why I’m here also. Since I tried recovering which was early last year, my gut has been acting up. By recovering I mean eating more and gaining weight. I have gained weight and am 25 pounds heavier then my og eating disorder weight, and am about 15 pounds heavier then my previous weight when I was fine having normal periods and all. So yes I’m still struggling with hormones they still seem a bit low, but I’m currently recovering from femur surgery I got for LLD, so my body is going to stress itself out and my hormones might also get even more out of whack. Anyway! Enough of that what I’m trying to get info on is my gut and if it’s just a simple problem to solve or something more complex. It really started this early year but last spring and summer when I was eating more I would obviously be bloated, I’ll struggle with constipation and things like that. It wasn’t so bad until thi year. I’m pretty sure I got the Noro virus last December in Mexico, that was not food poisoning because my family ate the same thing and I was the only one to get sick. It was the worst, coming out both ways and I was down for like 4 days and lost weight and super fatigue. Soon after coming back to the states, literally the week after I was super indigested. Was like that for about 5 days and went back to normal. The problem was also that I was trying to again gain all the weight I lost and trying to regain my period. Then I was stressed cause of school sports and never really had time to eat a lot during the day and basically was hoarding a lot of calories in the evening which wasn’t very good. I noticed heart palpitations, anxiety, bloating, stones feeling in my stomach, and sometimes constipation during the first few months of this year. And then bam this summer not only the symptoms keep coming but I then developed acid reflux and heartburn. There was days where I eat less and then days I ate more. Pretty much my gut was just stressing. Right now currently I’m still struggling with these symptoms, I tired probiotics didn’t work, tried aloe Vera juice and it kinda helped. I then started taking black seed oil 2 weeks ago with leaky gut pill that contain L- glutamine and marshmallow root with something else. During the first week of taking them my acid reflux and heartburn went away, I was less bloated. But then the symptoms came back, and I noticed they came back after stressful life situations. I’m currently recovering from LLD surgery so I’m not sure if I can take the supplements will ask tmr the doctor or surgeon. It sicks since I can’t move around at all so I can walk for the food to go down or workout. Right now I’m just trying to not eat 3 hours before bed, not lay down on my back after a meal or food, and not eat past fullness. Has anyone struggled with something similar? I know it’s a lot to take in but a little infor and tips won’t hurt:) thanks!
I’m working on healing my gut disbyosis but a lot of foods that are supposed to help the gut also cause histamine reactions in me and I think I have some oxalate intolerance too. How do I approach this? Do I keep eating all foods until my gut is healed and maybe the intolerance will go away or do I keep doing a super restrictive diet that is not doing much for my gut health? Anyone who has experience with this please help me out thank you!
Can you share your experiences if you had some with BPC ? I read its very good for leaky gut
Lmao this is probably really stupid but like theoretically if I killed most of the bacteria on my skin, and then rubbed faces with someone with really good skin, would that potentially help give me a good face microbiome ?
I'm thinking in similarity to like FMT after taking antibiotics
Anyway yeah probably idiotic but wanted to hear thoughts lmfao
https://doi.org/10.1016/j.micres.2024.127966
Abstract
Bifidobacterium longum (B. longum) is a species of the core microbiome in the human gut, whose abundance is closely associated with host age and health status. B. longum has been shown to modulate host gut microecology and have the potential to alleviate various diseases. Comprehensive understanding on the colonization mechanism of B. longum and mechanism of the host-B. longum interactions, can provide us possibility to prevent and treat human diseases through B. longum-directed strategies. In this review, we summarized the gut colonization characteristics of B. longum, discussed the diet factors that have ability/potential to enrich indigenous and/or ingested B. longum strains, and reviewed the intervention mechanisms of B. longum in multiple diseases. The key findings are as follows: First, B. longum has specialized colonization mechanisms, like a wide carbohydrate utilization spectrum that allows it to adapt to the host's diet, species-level conserved genes encoding bile salt hydrolase (BSHs), and appropriate bacterial surface structures. Second, dietary intervention (e.g., anthocyanins) could effectively improve the gut colonization of B. longum, demonstrating the feasibility of diet-tuned strain colonization. Finally, we analyzed the skewed abundance of B. longum in different types of diseases and summarized the main mechanisms by which B. longum alleviates digestive (repairing the intestinal mucosal barrier by stimulating Paneth cell activity), immune (up-regulating the regulatory T cell (Treg) populations and maintaining the balance of Th1/Th2), and neurological diseases (regulating the kynurenine pathway and quinolinic acid levels in the brain through the gut-brain axis).
Hello guys, i want to start eating L.Acidophillus on daily basis, but have been wondering if introducing a large number of L.acidophillus on daily basis will kill other beneficial colonies of healthy bacteria like Bifidobacteria, other L . microbes and Streptococcus thermophilus for example ?
Im from Bulgaria and have consumed tons of L . Bulgaricus on daily basis and it was never a problem, but i have had H . Pylorri in my teen years and i suspect i may have SIBO, which hopefully will get taken care of daily Yogurt consumption
I wanna say that i have consumed soil based probiotics, kombucha ,sauerkraut , kefir and different strains before but for short periods of time
I just ordered some L-glutamine pills but they're only 500mg and i seem to see most people suggesting 5g+ daily - any thoughts on this. Will 1g per day (two of my pills) even have an affect?
Thanks!
Hi all, would love to hear from the collective wisdom about this study from Monash which identified NRG1 as a (the?) molecule responsible for repairing gut lining. Feeling lazy / brain fog right now, so I can't interpret much more than "more is better". I also couldn't find much discussion about Neuregulins in the context of gut disorders on reddit or other forums.
What I did find so far suggested the usual mandate of balanced diet, exercise, fiber and probiotics will improve NRG-1 levels.
Sources:
Monash article
https://www.monash.edu/discovery-institute/news-and-events/news/2020-articles/how-to-repair-your-gut
Exercise and diet on rats
https://pmc.ncbi.nlm.nih.gov/articles/PMC4500351/
Fiber and probiotics on schizophrenia patients
https://pubmed.ncbi.nlm.nih.gov/38701375/
Preterm infants have compromised guts and have life long issues with immunity and digestion.
I am looking for suggestions to build a good microbiome for pre-term infants. There are two kids in our family, both pre-term, one is a special child. They are 14 and 16 now. I want to help them build a strong microbiome. I have already started with a diet program with them with high fibre, less processed food and other lifestyle changes
Any help with a protocol, supplements and other ideas would be greatly welcomed.
I have dealt with / masked bad breath since my teens by eating sugar free chewing gum. This is kind of nonnegotiable for me in order to function at work etc.
While I suspect the bad breath is there in some form all the time, it seems to be linked to constipation. Some times I can feel it being really bad, and notice others noticing, at other times things are better and people lean in close to me without seemingly caring/noticing. Linked to bowel movements.
The last few years I have developed some form of GI problem that is caused/worsened by chewing gum, so I am in somewhat of a dilemma.
At home I do not use chewing gum, but at work I always do. At the weekends my gut is much better than when I am working.
Any thoughts, experiences, suggestions?