/r/HumanMicrobiome
This sub is a haven from the flood of misinformation that is widespread on Reddit and over much of the internet. We have an evidence-based focus on the complex ecosystem in our guts that regulates the entire body.
This sub is a haven from the flood of misinformation that is widespread on Reddit and over much of the internet. We have an evidence-based focus on the complex ecosystem in our guts that regulates the entire body.
We encourage you to post on the Human Microbiome forum https://forum.humanmicrobiome.info/ and then link to it here.
Related:
Animal studies with implications for humans are allowed.
Health/medical discussion related to the microbiome is allowed, but may be restricted if it becomes too dominant. For general health try:
/r/Maternity's wiki.
FYI if you mention this sub in /r/science your comment will be silently, automatically removed.
Full rules and submission guidelines: https://old.reddit.com/r/HumanMicrobiome/about/rules/
Excessive rule breaking may result in a ban.
Fantastic microbiome 101 podcast by Yale, 2016. An excellent 2018 one by The Quantified Body and Richard Sprague.
MicrobiomeDigest.com - Group of researcher's daily digest of Microbiome papers. - Highly recommended!
Intro/summary & links to information on the significant, long-term, possibly permanent, damage being done from antibiotics, poor diets, lack of breastfeeding, etc..
Age | Aging | Antibiotics | Archaea |
Mucosa |
Peptides | Phages | Probiotics |
Review |
Small intestine/upper GI | Sex differences | Skin |
Testing |
Weight |
You can use sci-hub to access paywalled studies.
Our mod logs are public: View. Our mod ethos is "transparency; community run".
/r/HumanMicrobiome
My friend has had stomach issues for years, over a decade. She has seen so many doctors, no one could figure it out , test after test. She finally went to see a doctor known for figuring out problems when no one else can, and the doctor ordered her tested for H. Pilory. She tested positive. Turns out 50 to 75% of the Earth's population has it. Now she is taking medication for it. How is it possible that this bacteria is not a common test for those with stomach issues???? Has anyone else been tested for it?
So I recently came across threads talking about how people had a root canal and it wasn’t done right and they are experiencing stomach issues?
Now if you look at my profile history it was a crazy train wreck story back in 2020. I actually had a root canal done in 2020 because my idiot self would bite my nails and use it to take food out in between my teeth ( I know I’m a idiot )
But that’s how I got an infection in that tooth. I had pain in that tooth the next day had got it fixed and a crown over it. During that time I had crazy stomach issues I couldn’t explain.
I did mastic gum and homemade kefir and healed myself after a year of suffering.
But now it’s 2024 and my problems have came back. I done literally everything you can think of, kefir, homemade bone broth, mastic gum, ginger etc. but none of that stuff is working or making me feel better. I just get more reflux and anxiety!
So I wonder if my root canal could be infected or have bacteria growing there? I don’t have pain in that tooth. But I do read that you may not have pain there if you had a root canal..
I do wanna note that my oral health isn’t the best but it’s not bad. Also the tooth that I had the root canal done kinda have a smell to it. And I don’t know why. So I made a dentist appointment to see if it’s the problem causing all my issues.
Has anyone had this problem?
CGN LactoBif 65 is the one I'm looking to try (already have it laying around). I've had positive effects from other probiotics/probiotic foods, which made me interested.
Hi everyone,
I’ve been dealing with a complex health situation for a while now: SIBO is confirmed, my Zonulin levels are at 3200, and my secretory IgA is 2652. Despite a gluten-free, anti-inflammatory diet, I’m still facing persistent issues.
I’d love to hear from others who have had similar challenges—what really helped you in healing your gut? What specific steps did you take to see real progress after a few months? I’m looking for systematic approaches that lead to tangible results.
Looking forward to hearing your experiences and advice!
Ive been prescribed Doxy and Azithromycin from two different doctors for a respiratory infection and i cant decide which one to take. which one has less of an impact on the microbiome?
Good morning my friends, I am an UC patient for than two decades . I was on Humira (Amjevita) 40 mg, did work for me. I am on Sky Rizi injection now. I have 3 packed and each of them have 2 pens of Amjevita (Humira), good expiration date, and untouched. If anyone is on Humira and working for them, feel free messaging me . I live in USA, south California, and Los Angeles/Glendale. Will be donation. Thank you. ♥️🙏🙏🙏
If I eat greek yogurt do I need probiotic pills?
I picked up something from the floor, where there were most likely particles of street dirt brought in on my shoes. And then I ate a sandwich without thinking. What is the chance of getting deadly parasites and what should I do?
I have severe insomnia, Long Covid and ME/CFS. I know that with the right donor, I could possibly feel better. I can't afford Taymount or any of the organizations that mail capsules or enemas. If I were to go DIY, I would test my donor thoroughly and be sure to follow strict practices to keep the procedure safe. But, I'm VERY concerned that I could just make matters worse. My gut, as unhealthy as I'm sure it is, doesn't give me any problems except occasional constipation. No pain, no bloating, etc. Is it worth the risk? I'd love to get some opinions on this.
I have a history of colon cancer, GI surgeries, C. Difficile infections, sepsis, mental challenges (ptsd, anxiety, depression, ocd, etc.), as well as mild autism spectrum disorder (I guess that they used to call it "Aspergers").
I'm currently on Entyvio for IBD induced by my cancer treatment (I was having diarrhea 4-6 times a day) but I'm wondering if there's other things that I should he doing to improve my gut health?
I've heard that gaps can be good for mental health as well as autism spectrum disorder.
Right now, I'm eating a WFPB diet. I did a bit of keto/carnivore but it wrecked my sleep which in turn made me irritable.
I'm waiting on seeing how the Entyvio effects me but I can't help but worry that my diet is causing damage to my poor gut.
I have pretty bad anxiety. The question is, is it my bad gut causing my anxiety, or is it my anxiety causing my bad gut?
I had a GI map test done and it showed moderate to severe leaky gut along with blood in the stool and some other issues like non-pathogenic parasite.
I guess I'm wondering if a better (or more optimal) diet can improve my mental health or is it likely to make it worse due to over obsessing?
Thanks
I bought an expensive probitoic supplement ($180) and I've been storing it in my parents fridge.
Come to find out, the fridge was full of moldy food and spoiled items. It also had some animal blood in it.
I found this out when I did a deep cleaning of it yesterday.
Should I toss the probiotic? It had a cap on it. It was stored in the fridge for about 5 days.
What’s the best probiotic to take for gut health?
Long story short I have SIBO (I do believe it improved but isn't gone) and a lot seems stress induced, at least that's when my flares are the worst. A functional dr put me on probiotics including lactobacillus and then saccharomyces boulardii. I had to stop the lactobacillus blend because it caused CV (it appears like a yeast infection). I've been breaking out on my forehead and now around my eyes. I've always had acne, but not in these areas. The dr says I'm detoxing, but this seems unlikely as I've been on this regimine for months. Is this something either of these can cause? I haven't had skin this bad in years and take rx adapalene but it seems like it just doesn't work anymore.
Could this be a herximer reaction?
I may be due to get one but I’m a little scared about what I traits might be passed to me for mine donor
So I’ve dealt with SIBO and since gotten rid of it but had such bad anxiety & fatigue because of it. I was told to start a probiotic and it’s been great in terms of energy and anxiety almost gone. But the side effects above are making me rethink what I’m on. I’ve been taking it every day for over a week. The one I got was the bioglan platinum 20 billion gut health which has:
Each Hard Capsule contains: Bifidobacterium animalis ssp lactis (B-420) 400 Million CFU Bifidobacterium lactis (Bi-07) 300 Million CFU Bifidobacterium infantis (Bi-26) 100 Million CFU Bifidobacterium lactis (BL-04) 1 Billion CFU Bifidobacterium animalis ssp lactis (DSM15954) 1 Billion CFU Lactobacillus rhamnosus (GG) 10 Billion CFU Lactobacillus rhamnosus (HN001) 500 Million CFU Bifidobacterium lactis (HN019) 2 Billion CFU Lactobacillus acidophilus (LA-14) 200 Million CFU Lactobacillus casei (LC-11) 400 Million CFU Lactobacillus gasseri (LG-36) 100 Million CFU Lactobacillus plantarum (LP-115) 1.7 Billion CFU Lactobacillus paracasei (LPC-37) 1 Billion CFU Lactobacillus rhamnosus (LR-32) 100 Million CFU Lactobacillus salivarius ssp salivarius (LS-33) 200 Million CFU Lactobacillus acidophilus 1 Billion CFU
Hello everyone,
I’ve been dealing with Candida overgrowth in my gut for the past few months, and I’m looking for advice on how to normalize my stools and improve my microbiome.
I recently had a stool test that showed 70 colonies (with only 20 considered normal). My symptoms include occasional loose stools, anxiety, and panic attacks. I’ve tried the Candida diet and took oregano oil for 20 days about four months ago, along with a short course of Nystatin. I’ve also started making homemade kefir and plan to incorporate sauerkraut, kombucha, and sourdough into my diet.
As a pescatarian, I typically consume a decent amount of fiber, but I’m looking to increase it further. I tolerated carbs well before this overgrowth, and I suspect antibiotics may have disrupted my gut microbiome.
Has anyone experienced something similar? What strategies have worked for you in managing Candida and restoring gut health? Any advice on improving my stools and overall microbiome would be greatly appreciated!
Thank you!
As above. Ill cut to the chase. I had a surgical site infection in mid september that led me to having a minor surgical washout and drainage of a superficial abscess. I was then put on 5 days of Kefzol then 4 days of Ampicllian once lab cultures came back. Was discharged on 35 days oral amoxicillian at max standard dose.
I have found since going on antibiotics I am craving high fiber foods. Such as high fibre bran, whole meal bread, oatmeal etc. I have been focusing on my diet alot and have included fiber supplementation, pea protein, yougart, kefir etc. I am approaching the end of the therapy which totals it to about 6 weeks of antibiotics. Symptoms such as cramps and diarhea have been transient and minimal so far and I can count on one hand the amount of times I had watery stools
Is this craving just psychological or does gut bacteria composition play a role?
We are looking for young people aged 12-17 years from all around the world who suffer from chronic stomach symptoms, including chronic nausea, vomiting, pain, and gastroparesis.
Participation is easy and completely anonymous. The study involves a 15-minute anonymous, online survey that includes questions about your demographics, symptoms, and wellbeing. Your survey responses will help researchers and doctors better understand and treat young people with chronic stomach problems.
*We are especially in need of more males to complete this survey*
More information about the survey and the survey link can be found here: https://auckland.au1.qualtrics.com/jfe/form/SV_8fibsg84DNDz3lY
This study is being conducted by the University of Auckland in New Zealand and has been approved by the Health and Disability Ethics Committee, Northern A, on 24/04/2024, Reference Number 2024 FULL 19553.
Because of a chronic UTI, I've been on many rounds of antibiotics since February of this year. I don't know the exact number because this has gone on for so long and become a blur but it might be upwards of 7-10 times with all the different antibiotics. I am also going to start hiprex soon but I don't if that affects the good bacteria. Basically, I have very little money so I want to make sure that whatever probiotic I get that it at least has a chance of working. Please let me know some good ones.
Also, how long should I be on the probiotics for? And will hiprex counteract it?
Hello,
Long story short, I got SIBO after food poisoning several years ago. Initially, I thought I made something with probiotics ingestion, but then GI map shows extremely high levels of E. Coli (Enteropathogenic E. Coli). I tried many treatments during the years (antimicrobials, antibiotics, antifungals etc.), but nothing helped significantly. Even worse, my microbiome was wiped and got different sensitivities (salicylates, oxalates, sulfur etc.).
So, I decided to give a try to FMT (oral / rectal) from a clinic, which tests and monitor it's donor. I've done a course of 10 days treatment with Vancomycin to clear, followed by 5 days waiting to clear the antibiotic and then laxative (basically, colonscopy like prep before FMT).
Then, I got the FMT in the clinic rectally and orally at the same day. I felt relaxed afterwards and had a good sleep. Two days after I took another liquid solution (orally), as I got no bad reactions whatsoever.
Now almost ~2 months after, I continue to have yellow stool (fat malabsorption) - TUDCA/UDCA/Ox bile just worsen that. So, my doctor decide me to use frozen solution - basically, he prepared FMT with glycerol (frozen) and gave it to me (I am storing it at home at -22 C).
I have started to take 1 capsule per day (~700-800 mg of FMT orally). The reactions I got are mainly joint pains and stomach gurgling (like really noisy), but still nothing crazy.
I am taking it for about a week and I started to notice increase of overall malabsorption (food pieces in the stool, fat malabsorption, yellow stool etc.). I feel extreme hunger after a big meal, which indicates serious malabsorption.
However, at the same time my salicylate sensitivity dropped a bit, H2S doesn't seem to be SO hard as before and I am confused.
I am concerned because weight loss is there and I can't afford too much, because I already lost weight with SIBO for so many years. Dosages that I am taking a way too less compared to what they gave me initially.
Hi,
Just recived the microbiome results,and i m scary because i have high biliar acids,ancylostoma parasite,methane,fungi,mold,inflamation,infeections.
What is the root cause for high biliar acids?
Thanks
So there is one report on someone curing Androgenetic Alopecia (typical receding hairline pattern) reporting that a FMT helped them. There are I believe two studies that report Alopecia Areata (Patchy hairloss across the body and scalp in seemingly random positions) growing their hair back.
I was interested in knowing if anyone has done a FMT or taken probiotics and seen regrowth of hair in the scalp?
The reason asking is because the I imagine the Gut Microbiome produces some resources to maintain a healthy scalp enviroment. During aging process the diversity of the gut also decreases. This would lead me to believe some of the bacteria that helps produce resource for a healthy scalp would maybe die out, which in turn causes the hairloss.
Thanks for reading this.
What probiotics and yeast kefir contains And what probiotics and yeast kefir does not contain and needs to be suplemented?
Hi I'm don't know much about probiotics except that I've gone to Sprouts or WholeFoods in the past and just bought Jarrow or something similar (both refrigerated and not). I guess I've read conflicting things about whether these things are useful and even survive stomach acid.
That said, my motility is low and at times when drinking kefir or magnesium can become more a daily output person. Otherwise I can get constipated, certainly air gassy with cheese and pizza (not smelly though). I used to feel bloated but not much anymore.
I took alot of antibiotics a couple of years ago (doxy, a few days of cipro, bactrim for 5 weeks, flagyl, maybe 1 or 2 more -luckily no c. diff). after 20 days of doxy, a medical scare led me to have anxiety and insomnia, the latter which continues to this day with 4-5 hours of natural unaided sleep vs 7 to 8 before. Melatonin and seratonin are majorly affected by the microbiome so I suspect my body is still not right.
2 Genova Diagnostics tests done a year apart show lower Akkermansia. I'm game for trying Pendulum but see that some recommend pairing it up with other pro/pre biotics. Can someone help me out and give me the digest recommendation? I'd hate to have to start reading this sub backwards for a year.
Thanks