/r/Microbiome

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Welcome to r/Microbiome :)

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The Microbiome Reddit

Microbiome - an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multicellular organisms studied to date from plants to animals. A microbiota includes bacteria, archaea, protists, fungi and viruses. Microbiota have been found to be crucial for immunologic, hormonal and metabolic homeostasis of their host. The synonymous term microbiome describes either the collective genomes of the microorganisms that reside in an environmental niche or the microorganisms themselves.

The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genomic characteristics, sometimes collectively referred to as a holobiont.

Wikipedia: microbiome


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/r/Microbiome

81,904 Subscribers

1

100% perfect testresultat?

Hey People…

I was just thinking about this… We do all these damn microbiome tests. And they allways show something out of balance, right ?

Have anyone seen a test that is like allmost 100% perfect?

0 Comments
2024/04/02
23:47 UTC

2

My research on SIBO

So after having IBS for many years my symptoms got worse. So I started my own research on the topic. And found a new angle with SIBO. This list is absolutely not complete. But it’s quite some hours behind it even if it looks simple. I’m a biology teacher but absolutely not a doctor. This is condensed information that maybe can give some of you a new angle. Please feel free to comment the list.

SIBO can give: Histamine intolerance (take DAO/sprouted beans), Food hypersensitivity, Sensitivity to oxalic acid, Low values ​​of iron, B12, vitamin D, Also low in vitamin C and E, magnesium, selenium.

Makes SIBO worse: FODMAPs, Gluten, Fibers, Lactose, NSAIDs (paracetamol better), Hormone medicine (birth control), Beta blockers, etc.

Cause SIBO: Stomach infections, Antibiotics, Low food acid (medicine?), Poor intestinal motility (medications? Stress?), B vitamin deficiency.

Diet good for SIBO: Low FODMAP + Low Lectin, Basmati rice ok, Green leafy vegetables.

Three probiotics help (to heal the gut first): Lacto-Bifodo, Saccharomyces Boulardii, Spore based.

Reduce pain: Peppermint oil.

Heal the gut: L-Glutamine, Zinc Carnosine, Short fatty acids Butyrate.

Help digestion: Enzymes.

Reduce inflammation (step two when the stomach is a little better): Probiotics in spore form, IIG Immunoglobulins, Turmeric (also pain reliever), Cloves (also pain reliever), Caraway, Omega 3.

Increase intestinal motility: Ginger, Iberogast (also reduces pain/inflammation).

Herbs that kill bacteria take for 4-6 weeks (step 3 only when the stomach is so good that it can handle it): Oregano oil, Berberine, Bismuth, Pomegranate husk (also against diarrhea).

/Feel free to add to this list or comment it. It’s not complete but rather cherry picked “the best of”./

2 Comments
2024/04/02
23:01 UTC

3

Antidepressants

Has anyone ever healed there anxiety/panic disorder by healing there gut? And was able to wean off ok of antidepressants?

6 Comments
2024/04/02
17:13 UTC

20

Why are you readily to diagnose your own gut problems?

I am asking this because this can lead to many other symptoms such as anxiety ones. I have experienced this myself and I am now trying to seek a Dr (gastroenterologist of course) always instead of telling myself I have all sorts of gut problems, eg., disbyosis, IBS, IBD, messed up microbiome. etc. scaring yourself will only lead to more symptoms since now you are anxious which releases all sorts of stressing chemicals.

I know some of you all will say that Dr never treat the root cause but if you go to the Dr now you know what you have and you can manage it yourself with naturals rather than antibiotics. Sadly some things such as h pylori can never be eradicated without antibiotics. This is a dangerous thing so always great to be mindful.

Be kind to yourself and stop stressing yourself out since this cause more issues along the line.

68 Comments
2024/04/02
16:26 UTC

1

GERD and gut health

Does having gerd mean that my microbiome is shot or are these separate issues?

3 Comments
2024/04/02
14:08 UTC

14

I’ve caused too much die off

I am herxing and have been in so much pain I have so much inflammation all through my body. I was taking probiotics and was increasing too fast I guess and now I can’t really get out of it. It seems like the toxins keep recirculating. I have now stopped the probiotics of course. What would be the appropriate way to bind the toxins and support bile flow to properly get out of this recirculating toxic loop I’m in? I have leaky gut and I think it leaking the toxins in my bloodstream. Also my stool has been very light so maybe my bile isn’t flowing properly. Any advice would be greatly appreciated.

66 Comments
2024/04/02
13:42 UTC

1

Any experience with C innocuum?

Emerging consensus seems to be that this strain is quite pathogenic. Anyone what feeds/suppresses it?

0 Comments
2024/04/02
10:02 UTC

1

Probiotics turned my stomach upside down

Two weeks before I was planning to do a gut test I was adviced to go of my probiotics (which I have been on consistently for the past eight months to relieve my gi-symptoms).

when I stopped, my symptoms came back stronger such as stomach pain, fatigue and I felt sick for a week but, after this first week without them, I started to feel better again and it felt like the body had started to get used to living without them.

When i got back on the probiotics after i did the tests my symptoms creeped up again and now after a week on them my symptoms have become a lot worse with pretty bad abdominal cramps, feeling sick and going to the toilet five times in one day (I have always only been able to go once per day) and these symptoms haven't subsided yet (a week later). Maybe should I wait a few more days (if that's how my stomach needs to adjust) or take a lower dose, or should I stop immediately? (I haven't had such strong symptoms in a very long time)

20 Comments
2024/04/02
09:37 UTC

1

White tongue

I've been taking lactobacillus and Biffidus 2 wice daily with food for 2 months I don't eat until after lunch.

Constipation and stool quality have slightly improved

My phlem is white and foamy but becomes clearer later in the day. If I do any physical activities even a gentle walk it gets worse.

Any ideas. I already believe I have candida but swabs were clear and you'd think the probiotics would have helped not made it worse. Cortisol sensitivity and insulin resistance could also be at play.

Any ideas

Thank you

1 Comment
2024/04/02
09:02 UTC

7

Probiotics after Antibiotics Controversy?

I've seen multiple references claiming that probiotics post antibiotics actually do harm.

Here's an article as an example which discusses it: https://stephenskolnick.substack.com/p/so-you-have-to-take-antibiotics-how

Here's a study which was referenced: https://pubmed.ncbi.nlm.nih.gov/30193113/

One rather informed commentator notes the faecal microbiome may differ from other sections of the intestine and the study references faecal only post 21 days.

I've taken multiple antibiotics for three weeks and will be finishing soon, so planning my recovery. I was considering a 500 billion CFU 14 strain probiotic for 7 days to help move things along, but perhaps that's a bad idea!

Has anyone researched this and have an opinion on what the best course of action is?

6 Comments
2024/04/02
08:11 UTC

2

Fermented foods

So from my understanding fermented foods mostly contain lactobacillus bacteria. What I wonder is if there is also bifido bacteria in some of the common fermented foods? (Sauerkraut, kefir, kombucha)

Why I am asking is because I know from a stool test that I am low in both lactobacillus and bifido bacteria and would like to find a source that hopefully contains both. At the moment I have some saurkraut every day but am worried that I might be only getting lactobacillus?

1 Comment
2024/04/02
07:39 UTC

4

Cannot for the life of me figure out what is wrong and it’s driving me crazy (Levaquin issue)

Had a really bad sinus infection that landed me in the hospital with dehydration and they gave me an IV and an antibiotic. Did my 7x 500mg Levaquin and for 2-3 days after it ended I was still getting dizzy and nauseous. Finally felt better after a week so I went out with friends and drank last weekend. Wednesday rolled around and I got very dizzy and nauseous on the ride to work and ended up in the hospital again last week. They gave me an IV and said everything else about my bloodwork was perfect.

The issue is, now 5 days after my last hospital visit, my vision and head just seem a bit off. When my eyes are adjusting a lot and looking around, I get lightheaded and a little dizzy again. The doctor at the hospital said it will just take a bit to go away but this just seems so odd to be lightheaded so much. Didn’t think a CT scan was necessary either. I’m going to the optometrist tomorrow to check my eyes out and maybe get new contacts but my eyes and head were fine before this.

Could this be an issue from the Levaquin?

29 Comments
2024/04/02
02:59 UTC

3

Gas immediately after consumption of sugar

For some reason, I get gas just minutes after I consume sugar. I am recovering from a Giardia infection, took antibiotics. Is this normal? I know a lot of people have long term gut troubles after Giardia, could this be a symptom of that?

11 Comments
2024/04/02
02:26 UTC

1

Increased anxiety/ intrusive thoughts / depression after Covid , any info on causes or treatments ?

I got Covid in January, previously I was very stable, motivated, happy, calm, enjoying life.

A couple weeks after Covid in January my anxiety ramped up , and I developed insomnia. I take a medication that previously made me drowsy but now has little affect. Do you know of anything that can help ? Or what causes this ? Has anyone else experienced this ?

5 Comments
2024/04/02
01:20 UTC

4

How to increase absorption?

I’ve been trying to put on weight for the past 2 years, stagnating at 6’1, 72kg.

I consistently eat 3500 calories on days I don’t work out, and around 3800 on days I train, which is around 3x a week.

I know for a fact I’m not overestimating my calories, so what could be the issue, and are there any supplements that would solve it?

My first thoughts are sensitivity to either dairy or gluten, neither of which I’ve left out for long enough to see a difference.

Other symptoms are chronic tendon pain, bad breath which tends to come from the stomach, and hair loss from head, eyebrows, eyelashes.

Waiting for a doctors appointment as I write this, but thought I’d see if anyone has any ideas? I’ve been trying to put on weight for the past 2 years, stagnating at 6’1, 72kg.

I consistently eat 3500 calories on days I don’t work out, and around 3800 on days I train, which is around 3x a week.

I know for a fact I’m not overestimating my calories, so what could be the issue, and are there any supplements that would solve it?

My first thoughts are sensitivity to either dairy or gluten, neither of which I’ve left out for long enough to see a difference.

Other symptoms are chronic tendon pain, bad breath which tends to come from the stomach, and hair loss from head, eyebrows, eyelashes.

Waiting for a doctors appointment as I write this, but thought I’d see if anyone has any ideas?

3 Comments
2024/04/01
23:22 UTC

1

Negative Celiac ttg iga but high total iga

Anyone experienced an elevated IgA? I have anxiety and wondering if I should be concerned. Have some stomach issues such as excess gas , smelly gas, and narrower stools ( not pencil thin) . Doctor did cbc, comprehensive metabolic panel, c reactive protein, and celiac panel. All test came back normal except for the total IgA . I was at a 539 . Normal range 80-352. Should I be worried?

3 Comments
2024/04/01
22:03 UTC

42

Gut problems after going vegan

I've been asking around about this for years, on the internet, with friends and my doctors. Nobody has been able to provide a reasonable explanation.

About 8 or 9 months after going vegan, I developed "IBS" (aka all tests and scopes are clean and no treatments are working. We dont know what's wrong with you). I didn't really attribute it to going vegan. I just thought I was getting sick for no reason.

It could just be anxiety (I do have anxiety) that caused it, but it definitely felt like a flip switched one day, and both my anxiety was worse, and my stomach was freaking out. I'm bloated 24/7 (literally).

I also met several other vegans who experienced this. Some of them fixed it by going back to eating meat. The problem is, I've tried eating meat to fix this, and it doesn't work. I've tried for extended periods, and I feel even worse from eating meat now than I do without it. I also just have a very bad intuitive feeling about eating meat, which I pushed through to see if it would make me feel better, but it hasn't.

I've tried almost every diet you can think of without any real lasting symptomatic relief. My last hailmary theory is that fake cheese/fake animal products might have destroyed my stomach? This seems like a stretch, though, because before I was vegan, it wasn't like I was super healthy.

I'm wondering if anybody has any insight into this other than "guess you have to just stop being vegan" because again, I have tried that, and for whatever reason, it's not working.

Edit: First of all, thank you to everyone for trying to help.

I should clarify that I'm not exactly vegan at this point. In my desperation of trying to fix this, I am more relaxed about it. I don't eat a lot of meat or cheese, but for example, I had like 6 pieces of sushi tonight. My gut issues remain identical to before this recent change. I'm just mentioning this because so many people keep saying "just eat meat" even though I explained above that I've tried that already for extended periods with no relief. Compared to the average person I'm definitely still way more plant based, I still avoid animal product for sure but not entirely, It's just like maybe 5% of my diet at most these days.

Edit 2: You guys. it is NOT SIBO. I was tested for SIBO, and the test did not come back positive, but, like many in the comments, they said "nah its gotta be SIBO" and treated me for SIBO anyways. The treatment changed my digestion, but in terms of fixing any of my symptoms, it did absolutely nothing. It's not SIBO.

176 Comments
2024/04/01
20:39 UTC

4

Keto + no raw veggies protocol - how long to see results in bloating?

My doctor put me on the following protocol to manage acne, constant bloating, anxiety/mood, inflammation, and chronic gut dysbiosis

  • keto diet with steamed veggies only (most eating meat and fats)
  • IgG2000
  • megaspore probiotic (alternate every other day with probiotic below)
  • therbiotic probiotic
  • s. Boullardi
  • vitamin d, k, zinc, magnesium
  • omega 3 fish oil
  • calcium/butyrate
  • phospholipids
  • b complex

Slowly adding in grapefruit seed extract

I’m also upping my water intake and exercise.

Overall, my acne and mood has improved significantly (yay!). However, the bloating persists and it never seems to go away and it seems like I’ve gained weight. Just seeking advice for how long it could take for the protocol to help with managing the gut dysbiosis to reduce the bloating. I started to take 2 capsules each of the probiotics but cut down to one to see if that would reduce the bloating but it didn’t.

13 Comments
2024/04/01
19:28 UTC

2

Thorne Test Shows Elevated E-Coli and Salmonella

As the title says, I received my results back. I show definite Gut Dysbiosis, and elevated levels of E-Coli and salmonella. I have ZERO symptoms of either. In fact, I have the exact opposite issues. I have scoured the internet for some insight on this but information is scarce. Could anyone offer some insight? Thanks in advance.

6 Comments
2024/04/01
18:17 UTC

3

Comprehensive guide to healing the gut?

Hello - I’ve been a Lyme disease patient for a few years now and have done a few rounds of heavy antibiotics. My stomach hasn’t felt the same since. Seems like everything I eat causes bloating, upset stomach, etc. I’ve eliminated a few foods as well. Wondering if anyone has a guide to healing the gut that really worked for them and helped? Thanks!

2 Comments
2024/04/01
16:37 UTC

5

Best gut microbiome tests?

I'm currently looking at MyBioma, Biomesight, GetTested Gut Health XL and Atlas Biomed. Anyone have any recommendations of what's best? I'm based in the UK

2 Comments
2024/04/01
16:18 UTC

2

How to heal bladder issues?

How to heal ongoing bladder issues after lots of antibiotics? Doctors don't do anything

11 Comments
2024/04/01
15:40 UTC

24

Can unexplained anxiety and dp/dr be caused by gut issues?

I developed both seemingly out of nowhere, it seems somewhat coincidental that it came on me when my diet was at its worst. When I was younger my diet was horrible (high processed diet) and I never had issues with anxiety. After becoming a coffee addict and eating like shit again I now have random nocturnal panic attacks with severe existential anxiety during the day. I also now suffer from intense derealisation as well.

Is it possible this could be some sort of a gut issue? I eat a lot of kimchi and sauerkraut and don’t notice much benefit.

27 Comments
2024/04/01
13:12 UTC

6

Dissociation/Anxiety Immediately After Eating

I’ve been extremely stressed lately and I experienced these unusual episodes that soon follow with food reactivity afterwards (won’t go into the episodes further as that’s another issue).

I have done an incredible amount of research and seeing doctors/doing all usual tests etc.

Anyway, after these episodes I get strong food reactivity that seems very inconsistent. It does slowly improve but it suddenly comes back seemingly out of no where.

Symptoms: Anxiety (in stomach), head throbbing (temples and sinuses, can feel pressure in head), dissociation/confusion, slightly blurred vision, can’t think clearly/brain fog, increased heart rate, sensitivity to light/sound.

The reaction is about 1-2minutes after eating, and significantly pronounced.

I have tracked my diet (reactions are inconsistent, as one food is tolerated one day and not the next), done tests to see if I am diabetic/pre diabetic, had brain scans, etc.

I have had a stroke in right frontal lobe previously, which is why I think I have these severe stress episodes - but after I have the it’s like my body is completely intolerant to food.

Currently undergoing Genetic Methylation Test and gut biome mapping.

Has anyone experienced similar symptoms? There aren’t really any answers on Google.

9 Comments
2024/04/01
08:32 UTC

7

Looking for microbiome test, any recs?

I thought Viome looked pretty good, but saw some older conversations here about bad experiences. I’m looking for metatranscriptomic sequencing, ability to access raw data, ideally multiple tests (I read that doing it every few weeks is a more effective analysis), foods to avoid and general guidance on diet changes. Speaking to someone would be nice but is not necessary. What is the best option?

9 Comments
2024/04/01
02:32 UTC

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