/r/Microbiome

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Welcome to r/Microbiome :)

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The Microbiome Reddit

Microbiome - an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multicellular organisms studied to date from plants to animals. A microbiota includes bacteria, archaea, protists, fungi and viruses. Microbiota have been found to be crucial for immunologic, hormonal and metabolic homeostasis of their host. The synonymous term microbiome describes either the collective genomes of the microorganisms that reside in an environmental niche or the microorganisms themselves.

The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genomic characteristics, sometimes collectively referred to as a holobiont.

Wikipedia: microbiome


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/r/Microbiome

87,709 Subscribers

3

Changes in stools after antibiotic and nsaid use

Last year, I took a week long course of Clindamycin and consumed a fair amount of 800mg ibuprofens all on empty stomachs mostly. Gave me what I consider leaky gut that healed after a couple months. Trigger foods were beef, pork, tomatoes, alcohol. It would cause abdominal pain that would subside with the consumption of ginger ale. Returned to normal after 2 months like clockwork. Still though, my stools seem to be noticeably different than what they were before the medications. They’ve been more of soft serve consistency, snake/sausage like vs the big, firm logs of produced most of my life. Will that part of me ever return the way it was or do I need to reintroduce a certain bacteria? I’ve been taking probiotics but not sure if that’s helping.

1 Comment
2024/06/05
21:39 UTC

1

Enterococcus Faecium Understudied?

Hey there. I wanted to ask if anybody knows whether Enterococcus Faecium is well studied, particularly with regards to which genes give it resistance to fluoroquinolone class drugs.

0 Comments
2024/06/05
21:25 UTC

2

Blastocystis hominis detox symptoms?

Hello everyone,

I'm taking S. Boulardii for 30 days to treat blastocystis hominis. I'm on Day 5.

Has anyone cured blastocystis with natural/herbal treatments (not antibiotics or pharmaceutical drugs)- if so, what were your symptoms during the detox?

There seems to be close to zero information on the internet (at least that I could find) about the symptoms when detoxing, so anything you can share would help!

I just want to get an idea if anything is happening or if it's not being killed off.

Thanks so much!

1 Comment
2024/06/05
19:09 UTC

3

Could anyone explain what this symptom of Gut Dysbiosis is?

So I did a FULL GUT Microbiome test. The results were high gut dysbiosis, High zonulin & high Klebsiella. Could it cause this below? or could anyone explain why these 3 being high could cause so much discomfort over the past year.

So I haven't eaten since yesterday evening and haven't had much pain apart from a nagging dull ache in my lower abdomen. Then all of a sudden out of nowhere I start getting ridiculously loud bowel noises, practically all in the same spot as I can feel it bubbling when I put my hand over it. Its literally like croaking, gurgling & groaning etc along with heavy discomfort. What the hell could cause that hafter being fine for 18 hours or so.

It sounds like somethings not happy and my gastroenterologist couldn't tell me what it is or how to fix it after having numerous tests, he doesn't seem bothered. Have had this for around a year now. Seems to be unrelated to food as I eat no gluten, dairy and always bland low fodmap stuff. Doesn't seem like gas so what the hell could it be. This happens randomly for about half hour then stops again. Definitely not hunger as it's not from the stomach?

Any insights from anyone or people with similar experiences, would love to hear from you.

Love to you all.

0 Comments
2024/06/05
17:14 UTC

8

What causes constant acid reflux and gas and intolerances to carbs such as: gluten, rice, potatoes, gluten free flours?

Hello, I’ve been suffering from terrible upper and lower GI issues for years, including chronic pain from acid reflux and EE. Currently doing AIP paleo and notice a lot of reduced gas from avoiding the foods listed. I plan on gettting a GI map because I think it may be helpful. But in the meantime anyone have any ideas of what’s causes these issues?

29 Comments
2024/06/05
16:09 UTC

3

Do good bacteria have biofilms, or only bad bacteria?

I'm currently taking Biofilm Defence and wonder if it harms all bacteria or only bad bacteria.

6 Comments
2024/06/05
15:26 UTC

2

Bio-K+ Probiotic Fermented Rice drink

Hi there i was wondering if this product was safe for a heavily immunocompromised person, i have a family member who is immunocompromised and was looking for a possibly safe probiotic that could be used. I check on the label on the drink and they made no mention to avoid it if someone is immunocompromised but when i looked at the "lacticaseibacillus" and "lactobacillus" strains that it has it seemed the jury was out on weather it posed a problem or not. These are the strains, lacticaseibacillus casei LBC80R, lacticaseibacillus rhamnosus CLR2, lactobacillus acidophilus CL1285.

Does anyone have an idea if these can pose potential problems down the line? thanks.

3 Comments
2024/06/05
05:41 UTC

5

Is it possible that I’m ingesting too much probiotics?

I love yogurt. I drink one yakult, one drinkable activia, and eat a sweeter yogurt for dessert every single day. Is this too much? I have had the best poops of my life and have been the least gassy I’ve ever been. This might be due to diet changes as a whole though.

4 Comments
2024/06/05
05:38 UTC

0

GI 360 Stool Shipment

Have had gastrointestinal symptoms for months, so ordered a Doctors Data 360 Stool test. Completed all the samples and packaged for shipping. The instructions said to refrigerate all samples, minus one which was to be frozen and strapped to an icepack they included when shipped.

However, the label they gave was for 2 days shipping. I dropped it off earlier today with the prepaid package at FedEx (they told me it would ship out same day) but I checked online today with the tracking and it seems they have yet to ship it out (although the estimated arrival time says "On Time"). Wouldn't the icepack and stool samples thaw out by the time it arrives? Would the test still be valid?

0 Comments
2024/06/05
02:32 UTC

10

high dose magnesium long term

For the past 3 months I have been taking 2000 mg magnesium oxide on a daily basis to help keep me regular (I have IBS-C and methane dominant SIBO aka IMO). Typically I take about 1000mg throughout the day and another 1000mg dose before bed. I find it is effective in combatting my constipation and doesn’t give me too much bloat or uncomfortable side effects. I know it’s a pretty high dose for daily long term use though. What are the potential negative side effects? I know I might become dependent on it over time but I already am pretty much reliant on it so it might already be too late. Would I gradually need more and more to see an effect or is it just that I would need to take my current dose (2g) essentially forever? It’s not that expensive so if there aren’t any compelling side effects or risks I’m perfectly comfortable taking it for the rest of my life essentially. Please let me know if I’m missing anything or if my high daily dose would have any bad long term consequences I haven’t considered. Thanks!!

8 Comments
2024/06/05
01:22 UTC

5

Could microbiome be to blame? Recently gained and lost food intolerances

Hey all, so I've been lactose intolerant for as long as I could remember, been taking dairy relief pills and all become sometimes even they don't help. I noticed in the past month or so I can no longer tolerate yogurt, including lactose free, it gives me a horrific time in the bathroom for hours lol... even as much as 1/4 cup of it. I also noticed whenever I have nuts I get this choking feeling in my throat so I'm wondering if I somehow developed an allergy to it???
But at the same time like... I ran out of dairy pills this week and was like "fuck it" and had some casserole with cheese, ricotta and milk and... nothing has happened. I'm not even feeling bloated. Normally I get nausea and diarrhea within an hour of it but I had it like 5 hours ago and nothing.

What the hell is going on with me??

I had to take antibiotics back in August for like a month due to a double ear infection (had to switch antibiotics three times cause the first two caused daily panic attacks) so I'm wondering if I'm still dealing with the fallout of that. Who even knows.

Any ideas?

0 Comments
2024/06/04
21:47 UTC

6

Probiotic species naturally found in soil

Seen some studies or talks regarding the Hadza tribe that they have such a diverse and unique microbiome due to consumption of SBOs from the roots they frequently consume.

What beneficial bacteria are commonly found on dirty root vegetables? Does this have application for modern humans?

15 Comments
2024/06/04
13:11 UTC

6

Probiotic on an empty stomach or with food?

Do you take your probiotics with or without food? Thanks 🙏

26 Comments
2024/06/04
11:59 UTC

5

Do microbiome tests give actionable results?

Will they tell you what to do to improve or is it more of a test to see if you are a mess or not?

Has anyone here been able to make their results better by following the suggestions and retaking a test?

4 Comments
2024/06/04
05:02 UTC

5

Probiotics to take on doxycicline

Over the years I've learned to prioritise my mental health over my physical one. I got prescribed doxycline for acne for a undecided amount of time. I'm not dumb and I researched this thing and found out multiple things, one of them is that it screws your mitochondria and your mental health, indirectly by messing your gut biome. I don't really care if it gives me stomach pain or that stuff but what ls worrying is the effects on the brain.

I plan getting out of this as soon as I can probably.

But meanwhile, what considerations should I take (People who know the med) and most importantly, in this sub, what should I do to avoid microbiome- brain permanent damage. Thanks.

16 Comments
2024/06/04
04:59 UTC

2

Is sleep apnea common here?

I've heard alleviating gut issues helps with sleep apnea? Can anyone confirm this?

1 Comment
2024/06/04
03:35 UTC

1

Microbiome stool test question?

Will mb test point towards sibo if I have sibo?

0 Comments
2024/06/04
01:46 UTC

1

Interperting Microbiome test

Hello,

I received my Flore test and it says I have basically no probiotics. I'm also a little high in the bad and low in the good bacteria.

Has anyone received a 0% probiotics? After covid I've had shingles and alopecia areata and developed diabetes. I've always been overweight but never in the range so I think covid pushed me over. Thinking gut health is all related and started eating Cleveland Kraut sauerkraut and will incorporate Kimchi too.

Any other ideas? I eat an animal forward diet and low carb.

The 0% seems scary and based on what I've learned about the gut health connection to immune system and possible link to type 2 diabetes it's all making sense. Am I crazy?

0 Comments
2024/06/04
00:44 UTC

2

Anyone use Venus fly trap tincture? I read about an incredible story involving it.

Scientist discovered a family in Chernobyl that seem to not be affected at all by the radiation and four generations were alive in good health. It was learned that a large part of their diet, including Venus fly trap where the scientist discovered this anti-aging anti-cancer properties. But when you read about it online, you can’t find jack squat about it’s healing benefits.

12 Comments
2024/06/03
23:49 UTC

5

Why do I feel better taking the shelf-stable probiotic than the refrigerated one?

TL;DR: I tried a high-potency, multi-strain, refrigerated probiotic at the advice of a GI specialist, and it made me feel worse than a single-strain, shelf-stable probiotic that I bought from the grocery store. But both have improved BM quality and quantity. Why does my body like one more than the other?

A text wall for you, with some context:

I've had bowel problems for basically my whole life (the classic poop-til-you-die-then-don't-poop-for-a-day pattern). I eat pretty well (decent daily fruit and veg, mostly vegetarian but some seafood and chicken when I feel like it, whole grains, fermented foods including yogurt and kimchi and kombucha and miso, the good stuff). I haven't identified consistent triggers like dairy, gluten, etc. I've also dealt with anxiety my whole life, so I've figured it's just nervous poops, even though I'll have bad bowel days on low anxiety days frequently enough to question a causation.

That said, thanks to finally getting good insurance, I decided to see a GI specialist to finally get things checked out. We both agreed that I probably have IBS, but just in case, I'm going to get labs done to check for IBD, UC, etc. In the meantime, the doc suggested I try Visbiome capsules. I was given a bunch of samples for free, and started by taking one capsule every other day for a couple weeks, then have taken one a day the past two days. I'm no stranger to probiotics, whether in fermented foods or supplement form. But man oh man, these ones feel... weird? I'm not pooping all day, but I've noticed a lot more acid reflux and upper GI distress, which is not usually my MO. I'm emetophobic, so this has not been a great side effect for me, to say the least.

Here's the twist: For the couple months prior to the doc visit, I had been taking Jarrow Formulas Ideal Bowel Support, after researching a bit about strains that seem to play nicely with IBS. (I hadn't taken probiotic supplements for a year or more prior to this, just eating fermented foods.) The Jarrow probiotic is bought unrefrigerated (though I refrigerate it when I get it home) and is just one strain, compared to what looks like 8 strains in the Visbiome, which needs refrigeration. I felt like the Jarrow product helped me poop regularly and with decent consistency, even on days when I would otherwise almost certainly have anxiety poops, without many side effects at all.

What do we think is going on here? Is the Visbiome just too strong for me? How is it that the potentially "dead" probiotic product works better for my body than the "live" one? Is the Visbiome triggering some weird histamine reaction that the other one isn't triggering? I'm aware of the placebo effect, and I'm not ruling that out as an explanation. I also know that the U.S. supplement industry is the Wild West, but I thought that Visbiome had some significant research behind it, though Jarrow is also a relatively well-known company. I'm going to take a week or more off all probiotic supplements, to let my body reset itself, but I'm frankly confused, and until I have a follow-up visit with the GI doc to discuss, I would love some internet help in understanding this.

7 Comments
2024/06/03
23:04 UTC

2

Allergy alternatives to Garden of Life

Hi guys, so I’m currently in the recovery period after c diff, I just finished my antibiotics like a week ago and I’ve been trying to do more probiotic supplements. I tried to Garden of Life 80 Billion CFUs Critical Care and it gave me an allergic reaction. However, I think it really helped my stool bulk up, and I’m trying to find other high dose brands of lacto and bifido that will be helpful now. Does anyone have any recommendations of highly reputable brands without prebiotics? I think I was allergic to the Acacia… not sure though. Thanks!

Btw, I’m currently on florastor and Bio-K probiotics.

1 Comment
2024/06/03
19:02 UTC

1

Probiotics side effects

I have just started taking VSL3# probiotic, once a day in the evening and I've noticed that I'm bloated after taking it. I've been taking it for around 10 days now. That bloating feeling would go away in the morning after a night's sleep but now it is constant. I also noticed that my stool began to be more mushy, sometimes diarheea even.

What do you think of this reaction? Is it a good thing, showing that I really needed that probiotic for my microbiome or should I stop taking it?

0 Comments
2024/06/03
15:54 UTC

2

Shelf stable vs refrigerated Probiotics

Are shelf stable probiotics as effective as refrigerator required probiotics? Which do you prefer?

1 Comment
2024/06/03
15:16 UTC

40

Why do people claim supplements don’t work?

I have chronic digestive issues after coming off keto. I deal with constant gas, bloating and constipation which weren't nearly this awful before I started keto. I did several tests, an endoscopy etc but nothing was wrong. I tried consuming probiotic food like activia, kombucha which barely has any effect. I started taking the Now probiotic pills a week ago and have had heavy meals since then but overall my digestion is so much better. I have already noticed a reduction in my gassiness and bloating.

46 Comments
2024/06/03
15:09 UTC

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