Welcome to LearnBioinformatics!

I enrolled myself in interdisciplinary summer school, it's supposed to cover different themes under bioinformatics and how to do data analytics on genomic and biological data. I'm CS grad so data part is not much of problem for me. In today's class, instructor started with genomes, and dna rna and cells etc ended with tutorial of TCGA.

I have never taken, biology class in my whole life. So the understanding of biological concepts was a little too hard for me. Do I have to learn all the biology stuff from primary school to become good at this? After today's lecture one thing is clear to me that nobody can cover all areas, the remaining themes of programl rthinopathy (ig it's eyes stuff) cancer and Pathology etc. Though I haven't explored all themes but of the top of my head, cancer & Pathology & brain disease excites me most. How should i go with the program, to learn the most from it. Any link helps additional course work etc would be very appreciated.

Thanks !

Hi, people can we please comment all the resources that one can/should use if they're entering the field of bioinformatics or must know about going ahead in the field?! Thank you very much.

So I've asked before what distro I should go with to start off with Linux, which I will primarily use for my Bioinformatics work (and later transition to as a personal-use OS), and I ended up with a whole array of options.

Now I'm stuck between Ubuntu (LTS, Pop OS), Fedora or Debian. I guess each has its own perks (but also downs).

I also learnt about containerization and how it could help resolve stability related issues.

I want to know if dual booting 2 different distros (with contrasting features) would be helpful to rid this dilemma, and if so, which 2 should I choose?

Hey guys,I am a first year student in btech bioinformatics and I need guidance regarding the course so can anyone help me out I don't know much about the courses specifics so it would be greatly helpful

hello. I need to to present a paper for my college assignment and the paper i have chosen deals with bulk RNA-seq analysis. It mentioned PCA analysis done to visualize the the 2 condition groups(control and diseased) under study and said that the samples for both groups lie apart from each other. which made me curious as to if someone was trying to oversee the progression of a disease and had divided the diseased samples into different stages of the disease, then would all the sample groups have to lie away from each other on the plot for it to be a sound transcriptomic analysis? or would it be okay if the different stages samples lied closer but were far from the control samples?

I'm a biotech student, and I'm really interested in the coding aspects, ai, machine learning, deep learning, and so on.

I'm starting with R and python, and I'm currently taking the CS50P and CS50R course to help me out.

Any advice on how to and what skills to develop in a biotechnolgist's standpoint, from biotechnolgists who are in similar fields? Thanks!

Some of the best resources to learn Bioinformatics that I refer to frequently.

I have 2 structures I want to align: a structure prediction made in AlphaFold3, and a reference protein from PDB. These are 2 structures that I know should be similar. I've aligned the 2 structures in PyMol (A -> align -> to molecule), but the alignment is waaaay off. It seems like one structure is misaligned from the other by like 90º on the z axis. Any ideas on how to fix this?

Hello! We're an organization that teaches AI-Literacy to K12, educators and parents. We annually hold info sessions on different topics.

On June 8th, we'll be holding a webinar that discusses bioinformatics and projects that students can do within this field, and what they can do with their creations (competitions, publishing research, etc).

You can register here.

Hope to see you there!

Hey folks! We’re a startup at the intersection of AI and animal health. Looking for a Bioinformatics Intern to dive into genomic and proteomic data analysis. Got skills in Python, R, or MATLAB? Passionate about pushing the boundaries in veterinary medicine?

This is an internship l with potential for full employment. Interested? Shoot me a private message to learn more!

online workshop would be preferred.. workshop of cloud, linux ,python , bioinformatics related,data science related

Hello, everyone. I haven't seen any posts for any recent study groups. I completed my undergrad in medical science and I'm hoping to switch careers from wet lab work to dry lab analysis. I want to study Bioinformatics every day in order to prepare myself for a Master's program. The application deadline for the program is October.

I'm looking for a study/accountability partner in a similar position. I intend to go through the entirety of the Biostar Handbook as well as complete an introductory Bioinformatics course on Coursera.

Is anyone interested?

I'm working in Biotech company as SE, my dream to become bioinformatician

Trying to compare two programs from John Hopkins (~$50k) and Maryland (~$20)

I don't understand much aside from the price, does it make sense to pay extra to go to top ranked university? Does it even help with employment later on?

Can you offer me a well-designed guide please.

Hi. I've performed multiple sequence alignment on mitochondrial genomes of primates using mafft and kalign. How can I tell which algorithm did a better job ?

I am doing my masters in bioinformatics,first sem. And I'm completely new to this since it has been only one month. I was given a task to download the Yeast dataset from https://archive.ics.uci.edu/dataset/110/yeast for predicting the cellular localization sites of proteins and apply different machine learning algorithms on this data. We were told to do this on orange software,which I'm not that much familiar with. I tried downloading the file,but it was a zip file,but I couldn't import this into orange software. And also I didn't particularly understand how to do this in this software. If anyone have any knowledge regarding the working of orange software,and how to prepare a workflow/pipeline in orange,pls do help . I googled it and searched in YouTube too,but couldn't find an answer. Please help.

Hello everyone! I'm doing a BSc in a healthcare subject but I want to do bioinformatics in the future. Where should I begin? Any sites especially with certificates would be appreciated. Thank you! 😊

hello, I have a bioinformatics project where I have to design cloning primers, and since the product is a fusion protein, I read that I have to omit the stop codon at the 3' end before i do reverse complementarity.

any tips on how can achieve this?

Some isoforms are %100 same but their id is different. Why is that?

Hello,

I am an early career research in clinical research. My background is in public health and epidemiology and clinical research. However now I would like to learn how to calculate polygenic risk scores from my clinical subjects. Does anyone know of an online course, youtube videos, etc (can be free or paid) that offers focused learning on polygenic risk scores? Courses on GWAS and epigenetics would also be beneficial, though not exactly what I'm focused on at this time.

Thanks

I HAVE AN EXAM IN 12 DAYS
AND started loking for previous years exams

and found this one

https://preview.redd.it/i742p96lxyac1.png?width=794&format=png&auto=webp&s=f62638bfbea50798424e48b0a0c1053a70bca8eb

https://preview.redd.it/dg1ds96lxyac1.png?width=794&format=png&auto=webp&s=97b32a9ea54b50d2a1d253034fcd1ac8c8a272d0

https://preview.redd.it/2cnobd6lxyac1.png?width=794&format=png&auto=webp&s=c17d54c28a929ce2b2f838beaa4fabfdfb382deb

https://preview.redd.it/qlrbqd6lxyac1.png?width=794&format=png&auto=webp&s=ded30ea1860f623fc50c939689fe8988654f314a

https://preview.redd.it/3oj9357lxyac1.png?width=794&format=png&auto=webp&s=ea905ae63eed74680ea14857d8f7af5a2da7080f

https://preview.redd.it/llbpl37lxyac1.png?width=794&format=png&auto=webp&s=cbee6dd76662234ddb306d3e54d56d928a914355

https://preview.redd.it/vvdr1b6lxyac1.png?width=794&format=png&auto=webp&s=308b7ea7ac7500dec7212f228828bd0367266000

https://preview.redd.it/nnq7qc6lxyac1.png?width=794&format=png&auto=webp&s=6ce60252eb0176dbd131cf7189b4a17d677a41e0

if any one can hlep me

i would appreciate it

thanxk in advanced

Hi all! Pure bioinfo amateur here who's starting his PhD on retroelements innate immunity. What would you say are the fundamentals I should master before delving into sequence curation?

Hey everyone, hope you're doing well.

After multiple customer discovery interviews and validating the problem. I'm starting to build BioLearn, a bioinformatics e-learning platform taht brings the best of udacity and datacamp to the bioinformatics industry, and I'm looking for a scientific co-founder.

I have over 5 years of experience in software engineering and I've been learning the business aspects of launching/running a startup for the last year.

No fluff here, it's an equal equity split based on responsibilities, qualifications and time commitment. This is to build a MVP and test the idea much further.

Who I'm Looking For: Someone passionate about bioinformatics with industry relevant experience, who likes teaching/education, and is willing to contribute with creating online learning material (the idea is to create 3 foundational courses on bioinformatics, data science and biology). You'll help build our courses and shape the future of bioinformatics education.

What's In It For You: Equal equity partnership. We're in this together.

​

A salary is out of question, I cannot afford it even for myself. Right now is all time investment for both.

​

If you're interested reach me out on LinkedIn and let's talk about this. This is my profile: https://www.linkedin.com/in/brian-rey/

Thanks :).

If I am comparing phylogenies and rates of evolution of 2 bird families across 3 different genes, should I have those 3 gene's protein sequences available for every single taxa in those 2 families or can the taxa availability differ slightly in each of those 3 genes?

E.g. I have 3 genes. I have 10 taxas total (5 in each family for simplicity). Should all 3 genes' protein sequences be available in every single taxa or can 7/10 taxa have gene 1 protein sequence available and 9/10 taxa have gene 2 protein sequence available and 6/10 have gene 3 protein sequence available.

So each of the 3 trees for 3 different genes will differ in the taxas they have. Is this a way to compare phylogenies when some taxa do not have a specific gene's protein sequence available?