My 2 cents on Isotonitazepyne, and, contrary to the majority of posts and comments I've seen, it does dissolve into a beautiful golden solution in just water. Rolling boil, 1 to 3 seconds, and to reduce that time and evaporation, a tiny a portion from a single use Vitamin C sachet, (not the entire thing,) and can get that down to merely reaching boiling point, under a second.

Do have the other hydrophobic variety for the same Isopyne that folks speak of, first experience with that for me. It's incredibly hydrophobic, lol and has very little aroma compared to and is a very fine powder. All I currently have to say on that variety as I haven't tried it yet, still waiting on the lab to come back, just to make sure, harm reduction. Can't advocate enough looking for if your country has maybe free but anonymous testing available, then folks know they're talking about the same thing. Not someone who got 1 thing that could technically have been anything.

Back to this stuff that comes back from the lab as; Major - Isotonitazepyne, Minors - none. When things are cut or mixed with something, if it's other than a RC, etc what have you, inert, such as flour or something lol, well, in such samples they come back with Majors or Minors present of either known active compounds or unknown non-active compounds. (I forget the specific terminology, but when it's a just a Major of what it was meant', with no unwanted Majors or Minors, this seesm to be a good result! :p

I speculate Isopyne that's on the more pure side, dissolves, or perhaps it's the synthesis itself that makes batches vary in solubility. Only know this stuff, thats results are back and she dissolves, very pungent chemical aroma to the prod, almost vinegar like, but not quite, just a strong aroma. It's beige/ colourless/ yellow (to me,) in clumps/ powder, to all outward appearances all of the same material.

Long legs, a shot lasts 24-36 hours. Dose, started at sub milligram, (that's 10 years on Opis, and 2 on Benzimidiazole Opis) however, now up to about 1mg per shot (of this particular stuff anyway). To compare a little, 90 - 110mg of Methadone was my last holding point, not taken any in a while. Compared to Protonitazepyne, (which for me dissolved at about 80°, turning visually to a slick oil like apparel just prior to distributing in the water and making a perfect shot, absolutely no vitamin C or citric acid necessary,) and yeah, Protonitazepyne way ahead of Isotonitazepyne for me. Ppyne has an amazing rush, better than Isopyne. But, since loved things because of so illusive, Iso is still the best there is, imo.

As said waiting on the results for the, new to me, hydrophobic powdered variety of apparently Isotonitazepyne. Happy to post an update here when the test comes in. I was told the potency of the hydrophobic was low, hearsay at this juncture, but when compared to this water soluble Iso the post is about. One theory is the hydrophobic powder is cut with something, well, hydrophobic, possibility to dissuade IV use. I don't know. Will see if the lab picks anything up in that hydrophobic sample.

Apparently, following the ban in China, not entirely sure if new Isopyne is being concocted. So could be the remaining is being diluted to spread it further.

Anyone else relate, the stuff in clumps, strong smell, dissolves in both just water, or with vitamin C or citric acid (if you want to minimize bringing it to the boil, but there's pharmaceutical grade varieties of those, so harm reduction)? 99% of the posts seem to be referring to the super hydrophobic, apparently same, stuff, which I couldn't relate to until recently but don't know if that one's Iso yet, waiting for results.

Lab Test Results should be visible on this post

How is adding LSD into the mix of these substances? Of course after trying them on their own. Is there any where you can just combine the 2 from the jump?

Since 6-apb and LSD have a similar come up, do you dose them at the same time?

5-mapb being a little different with duration and come up and so forth.

Also out of curiousity, can 5-mapb and 6-apb be combined? And if so can LSD be added to that combo or is there no benefit from combining both 5-mapb and 6-abp?

If anyone has done these combos (any LSD derivate like 1v-lsd, 1p-lsd, 1cp-lsd, 1d-lsd, 1s-lsd etc you know what I mean, even AL-LAD or LSZ, any lysergamide + 5-mapb or 6-mapb

I normally use ritalin fot work when there's a deadline and i need to code +-16 hours a day. Atm shit happened lost acces to Ritalin so had to improvise. Looked up online prices were 10/20x from what i would get in a pharmacy. Had to find other alternatives. Stumbled upon 4mph which is advertised as Ritalin without subscription so ye had to go for it. Some also said that nep was a could be use functionally and 3fea being an Adderall alternative so i bought a gram of nep and 2 pills of 125mg 3fea People online said to take a low dose of 4mph cause it's 3x potent but that shit is a lie its 3times less potent imo. I usually take around 30mg Ritalin. I had to take 2x25mg around 10:00 4fmph purple tablets just to feel something then 2 hours later redose with another 25 around 12:00. 15:00 After a while did research around nep and the reviews were very mixed and mostly bad. I know idk why I didn't do this before and just bought it cause of 1 comment. Still desided to do a small key bump of a gram on a plate and crush it, did 1/5 of that in a line. People warned about redosing and i was aware of it so One hour later i did another small line. I think i did 30mg max. There was some anxiety and uneasiness while i was trying to focus on work. 17:00 The i decided to fuck it and do 3fea instead of redosing on nep to make the anxiety and uneasiness go away. So i did 62mg of 3fea first then redosed an hour after with 33 and 2 hours after that with 33 again. Nothing bad happened. Will throw the nep away tho. Took a bromazolam at 24:00 and went to sleep.

Tldr: 4fmph is not as potent as it used to be imo 25mg 4fmph= 10mg Ritalin or even less. Nep= induces some anxiety and uneasiness which for me outhweighd the good stuff gonna throw it away. 3fea idk what to think about this one but just happy it took the anxiety of nep away.

Also if someone has advice for functional stims pls leave in comments, its for coding/work.

With the arrival of DMNPC on the market, I believe that the stimulant market might be shifting away from the phenethylamine structure due to bans and scrutiny. That being said, I wanted to ask: does anybody knows what these future stimulants could look like? I know of Dasotraline, which was being trialed for ADHD and has less serotonin reuptake than DMNPC at similarly stimulating doses. Is it possible we could see more stimulants based on SSRIs?

Also, some people here have expressed concerns over the intense SRI action of DMNPC, seeing as it could lead to stronger withdrawal effects and a higher possibility for serotonin syndrome. How valid are these concerns likely to be?

Sorry for the heavy questions, but I see exciting possibilities for the future of stimulant RCs which seemed to be stagnating a lot in the past few years.

Is it just me or do you see so many ''Rc noob'' posts, the time has come. its gone mainstream, i mean we kinda knew that with all the upcoming bans but itll be even worse now

Most of the websites I have visited don't do a good job of explaining what exactly each one does and its closest analog to other substances. I would love to find a chart or something listing the different categories , potentially including reviews.

Hi, this happened to me multiple times, i had my plasting bag with nep in it and I needed to hide it so i put it in my sock the bag was closed a I sweat a bit, and then when insuflatted it my nose was very numb and uncomfortable and the effects were totaly different, i was 4 days up my parents didnt even noticed but then i became like zombie and they found out, that nep was totaly destroyed, i started seeing many people( halucinating) and it was totaly disgusting and that happened with more batches... 3 grams i dumped in toilet, next time i will hide it somwhere else, do you know why that happend? , is it because sweat or what? The bag was closed i think.

Couldn't find anything of this on google. But I was wondering if I could dissolve 2-MMC in water to get a solution of 10mg/ml if I dissolve a gram in 100ml of water? Would be great if this is possible.

So if anyone knows the solubility let me know or if they have tried it themselves with 2-MMC

Bonus question: I know 2-mmc affects serotonin as well, but sounds like it's a lot more on the dopaminergic side rather than the serotonin side, have people mixed it with 5-mapb or 6-apb? Or what'd be a good combo?

Yes I know sero syndrome risk would still be there, but honestly I've partied with a lot worse combos in the days of my 18-22 when I used to rave a lol lmao. Just curious if it's possible because 6-apb surely would give more of the serotonin effect 2-MMC might lack according to many sources.

But anyway, can I dissolve 2-MMC in water for a simple solution?

Hello everyone, i’ve received a 0,5g free sample of JHW-210 in a powder form. So I already know what it is and the risk but i can’t really find any information about the dosage and also how to use it ! I mean i know it’s not supposed to be insufflated neither orally i guess so how can i use it ? Thanks to everyone for the answers i would really appreciate some help and TR if possible because i’m very interested in this noid !

hey all! my boyfriend and i have been experimenting with RCs, i already have experience with lsd and we both have experience with psilocybin (truffles) and weed. we have the following:

1p-lsd 150mcg blotters 2mmc powder 6apb 120mg pellets 5mapb 50mg pellets

yesterday we used some of the 2mmc and redosed for a total of 219mg on his side and 186mg on mine. listened to music and just chilled for a bit, effects after was just tensing up a little every now and then, some soreness on the lower back, a bit motion sick, feels like i was on a long car ride hahaha.

but i'd like to learn more just to be as safe as possible, things like dosage recommendations, recovery time between uses, tolerance, which are good for chemsex, which ones can be used right after another or even mixed, etc etc. neither of us really enjoy alcohol so we won't be using combined with it.

we have already looked around online and in-store for information especially before purchasing but would like extra tips if anyone with some experience can provide! we're trying to avoid bad trips and have the best experience possible and would also love to hear some personal experiences and activities we could enjoy doing during use, like walks, games, movies, etc. thank you!!

So I'm deff goin go to order 6-APB but I just noticed 5-MAPB is also super cheap, but NEP as well.

Never tried those, never been a real stim guy. Have done MDMA in the past and occasional cocaine but I really wonder what would be the most fun pleasurable experience? NEP or 5-MAPB?

My initial guess 5-MAPB because it's like the MDMA version of 5-APB but NEP also caught my eye.

Anyone that used both or can tell me what they'd choose and why let me know

is this a more effective way to absorb the chemicals? in my experience amphetamines are much more bioavailable anally but i wasn't sure how metmp are. I've also never tried boofing a benzo before. Anyone got experience with this?

So I was thinking about getting 2-MMC, Ii'm not really a stim user, but black friday sales and a gram of this stuff is super cheap.

I know 4-MMC is the king and 3-mmc next or whatever and that 2 substitutes are a lot less potent but I've read some stellar reviews on this substance.

Makes me wonder, so I appeal to the people who used 2-MMC what can I expetct and what kind of effects it has on you. Just so I can decide it's worth getting before the ban.

I've gotten offered mephedrone a lot by friends who got it from the black market so they don't really know what they're taking, the advertised 4-mmc could be 4-cmc, 3-mmc an dso forth.

Is 2-MMC fun ? Does it cause focus enhancement? On what ocassions is it ideal? (except parties). How obvious is it that you've used 2-MMC (since it's lighter than 4-MMC I was wondering if you could go with 2-mmc withotu anyone noticing that you've takne it lmao;

Also the ROA, many seem to go for sniffing but isn't oral higher availaiblity and beter to used? Does this have use as focus enhancement drug whilst simultaneously being a social drug?

So seen it has been called ‘ closest to mescaline’ but then again other compounds been called this.

Well, I have LSD, one 2c-ef pill left which was amazing and it being a phenethylamine it made me think about getting MAL instead of 2c-ef again. I can either get 10 pills of 2C-EF again which I've tried a lot before already and is beautiful but I wonder about MAL. I can get 10x21mg pills of MAL again or 0,25g fumarate but I have no scale fro measuring that so probably would go with the pills.

I know, there’s googling forums like bluelight (the big and dandy MAL thread), reddit and what not but I like some interactions and opinions of people who’ve tried MAL.

Synthetic Mescaline is really expensive, I can get it but it’s like way too much for basicallly 2 doses and I’ve had mescaline in the past so if MAL really is very similar or is an awesome compound I’d like to hear from people who’s experienced it.

If you have experienced please go in depth a bit, what dosage, how it was, what you liked about it, what I could expect to perhaps feel and so forth. As it's a psychedelic that's a lot like mescaline according to loads of people which is a psychedelic with not a whole lot of visuals to begin with but unique in it's own mescaline way.

So how is Methallyescaline? Worth it? Not worth it? The ban is on phenethylamines and a lot of fun substances is next month so

Has anyone tried this compound ?

https://en.wikipedia.org/wiki/N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate

Just saw it on site of one of the chinese vendors.

The stuffs real, when i use it in an OB or whatever it will blow my head off, but i decided id try put a gram in 1ml cart and its just not hitting like id expect it to, seems to be burning the stuff too.

Its a ceramic coil cart w/ ego battery

any ideas?

Good day fellows,

I'm looking into acquiring some DiPT, 5-br-dmt and LSZ, for a study. I'm wanting to look into the antimicrobial/anti-fungal effects of different indole derivatives (I also have some indole itself I'll be using.) my plan is to isolate trichoderma mold and then compare agar with different concentrations of the substances to determine if/to what degree they can inhibit colonization/sporulation of the trichoderma.

Bromo dmt and isopropyl tryptamine should be fairly easy to figure out/handle but I've never worked with lysergamides outside of a "cut the tab into 8ths for daily dosing" or "dissolve it in saline solution for eye drops" kind of situation. The LSZ will be coming on blotter, supposedly 150mics, so is distilled water usually sufficient for full extraction from blotter paper? Is LSZ similarly light sensitive?

There's also the apocryphal stories of LSD absorbing through skin, does anyone have links to data on that especially for LSZ? I haven't seen too many trip reports for that compound either, if accidental dosing does occur what can I expect relative to LSD?

Hello, Does anyone know, if you want to build of lorazepam, but your almost out of it and still on 3/4 dose. Wich rc should he use to build of further? Thank you for reading.

Yellow Mandala mix

Hey guys, recently acquired 2 vials of Yellow Mandala at a dutch smartshop. I was told it contains 120mg of 6-APB/Benzo Fury in 5ml liquid vials, equivalent to 1 dose each. Has anyone had any experience with this specific product? If so, how did you dose it and what was the ROA?

I have never tried this compound but I want to practice harm reduction and I am looking for tips from this community.

Me and my girlfriend love to roll and do so once or twice a year. We have only taken pure tested MDMA in powder/crystal form before. What differences should we expect? And what kind of precautions should we take that apart from the usual harm reduction practices associated with MDMA? Any kind of info is highly appreciated.

Thanks in advance! Knowledge is power.

Just wanna hear from other people, for me its 1P-LSD (changed my life), 4-HO-MET, 5-MAPB. Still wanna try some other stuff like 5-MeO-DMT but that shit sounds terrifying. I’ve done stuff like NEP and 3MMC but it was way too fiendish. 2F-DCK was nice too but I prefer normal Ket. What are some of your favorites?

What other drugs currently available are more like pyrazolam? Calms anxiety but still really functional?

No success was had insufflating 30mg, boofing 50mg and vaping 15mg of this substance on separate occasions. I was starting to doubt MET or at least the batch I have access to. Because of these previous experiences (or lack thereof) I didn't mind `wasting` material trying to just eat the stuff. I prepared a capsule containing 120mg of MET not expecting much of anything... I was surprised.

T0:00 — Capsule Taken
Ingested the capsule on an empty stomach expecting a mild experience and went about my day as usual doing some chores.

T0:40 — Subtle Signs
First signs of activity are noticed. Very subtle still.

T0:45 — Rapid Onset
My world is starting to rapidly change and I feel slightly nauseated. It's already becoming more intense than I expected it to become so I lay down and put on some music. The patterns in my curtains start popping out and moving independently from one another.

T1:00 — Peaking Hard
The intensity is still rapidly rising and I'm starting to wonder if I maybe made a mistake while measuring my dose. At this point I'm tripping absolute balls with visuals equal in intensity to my highest doses of 4-HO-MET. It is becoming an effort not to puke and I start to worry that I might completely loose touch with reality.

T1:15 — Total Immersion
Everything is altered. At some moments the visuals and high are so intense that I almost involuntarily close my eyes. With my eyes closed I'm presented with multi-colored, curved triangles interlocking into multiple curved surfaces that come together in a sort of focus point. I almost never experience closed eye visuals so I was pretty impressed.

T1:30 — Plateau and Stabilization
The nausea is subsiding and I'm starting to become confident that the intensity isn't increasing anymore. I start to relax and enjoy the experience a bit more.

T2:00 — Rapid Decline
As quickly as it came on the effects now seem to fall off.

T2:15 — Return to Baseline
The visuals are as good as gone and I have been left thoroughly surprised and impressed. I start writing this report.

The reason for writing this report is that MET is a relatively obscure substance so there isn't a lot of information on its usage online and to warn people not to blindly trust Psychonautwiki as I did. I would advice anyone interested to start with a lower dose to test the waters.

So I've been reading some really interesting stuff about combining 3-meo-pce with psychs and i have 25mg of 4-ho-met laying around.

I've had some experiences with both, highest doses being: 25mg of 3-meo-pce (oral) and 25mg 4-ho-met (boofed). Both were intense but fun and manageable experiences. Psy and disso combo i've only done with lsd and ket and i love it.

What dose and roa would be best? 3-meo's ungodly long comeup seems anti synergistic almost when combined to the instant boof comeup, but oral 4-homet gives me quite a bodyload and nausia for the first 40 mins.

Any help from people that have done similar combos is appreciated 👉👈

I'm on dmxe right now and am thinking of mixing it with al-lad and watching my favourite movie i havent seen in years but i have a few more dissociatives and psychs i can mix instead.

what rc or combos of rcs are best for just sitting back all day and watching a movie.

how is 3fa compared to meth? does it provide similar rush in higher doses?

Has anyone ever tried this rc and do you know is it smokable or do you just snort it or it drop it, a vendor has started stocking this rc and it seems really interesting would love to know more and also can you turn it freebase

N,O-Dimethyl-4β-(2-naphthyl)piperidine-3β-carboxylate (DMNPC) is a piperidine based stimulant drug which is synthesised from arecoline. It is similar to nocaine in chemical structure, and has two and a half times more activity than cocaine as a dopamine reuptake inhibitor. However it is also a potent serotonin reuptake inhibitor, with similar affinity to fluoxetine In animal studies, DMNPC exhibits similar potency as fluoxetine but with greater activity for DAT and NET. N-Demethylation of DMNPC has shown to produce a 3-fold increase in potency for 5-HTT This product is intended for laboratory research purposes only and are not to be used for any other purposes.

Hello, I'm not sure if it's safe to do, I made some research but didn't really found anything about mixes with Mal. Does anyone tried it or know if it's a great combo ? And if so, what could be a great dose ?

Or I'm just going to do 1p lsd and 6apb.

Thanks

I'm a psychonaut experienced with psychs, focused on harm reduction, responsible use and trying out new things. I've never had a negative body reaction to any psychedelic before and generally never had a 'bad trip'.

So 20 days ago I took ~12mg of Moxy orally, for the first time (trusted DN source). I know it can be considered a pretty high dose but I have a higher tolerance to tryptamines in general. I didn't mix it with anything nor was I on any meds.

The physiological reaction to it was TERRIBLE - to my huge surprise and disappointment. I had an agonizing vasoconstriction. It was so bad my balls went super retractile and my dick almost turned blue (it was the smallest I've seen it lol). I felt so much pressure in my entire body and my muscles were jerking and twitching all over the place. I eventually had to resort to killing the trip for the first time in my life.

After this unfortunate event, some of the muscle groups keep twitching non-stop, especially ones affected by neuropathy due to pinched nerves in my lower back. It is not painful, but extremely annoying and distracting. Also it worries me that it didn't go away almost 3 weeks after. I'm feeling more irritable as well and having increased anxiety levels ever since.

Has anybody had such a reaction to 5 substituted tryptamines? Any ideas on what the heck was/is that and what neurological mechanism could be involved in such a symptomatology?

I'm getting a bit concerned here and any thoughts will be appreciated. Thanks fellow riders!

I stimfap, like a lot when on it… probably because I love smoking it, lines and oral are good too, probably even better but there’s something poetic behind watching a crystal dissolve in a glass pipe so here’s my point:

Seems like the ban is coming for real this time and although I don’t do Nep that often anymore it’s still my favorite drug (a-pihp came first when it was still available, the memories…. pure powdered horniness and paranoia, great times) and before that happensI might wanna give it one last chance to abuse me.

Is there anything that can be done on it that will take my mind away from beating my dick to death? Anyone has had success with such practice? If so, please reply. If not, feel free to share your experience as it would be much appreciated to feel some closeness by a kind stranger.

Hey guys, so I have a couple 10mg 2cb-FLY pellets laying around and have been thinking about trying it out this evening. I‘d say like half my LSD trips end up being quite uncomfortable or unpleasant, I know people take Benzos to kill the trip or deal with the anxiety but I don’t do Benzos and usually just ride it out or try to sleep. Could ODSMT have a similar effect? Making one feel cozy and tip the trip into the right direction?

Maybe will take some 5-mapb alongside it instead of odsmt, we‘ll see. Can‘t have a bad trip with tons of serotonin being released lol