/r/researchchemicals
[STRICTLY NO SOURCING] subreddit for the discussion of synthetic psychoactive research chemicals a.k.a. Novel Psychoactive Substances (NPS)
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A dedicated subreddit for the discussion of psychoactive synthetic research chemicals.
Experience reports are highly encouraged. Check out Erowid for examples. If you find a great experience report on Erowid and want to post a link, that's also welcome.
Do also check out Psychonaut Wiki and Tripsit. Both are superb resources on novel compounds.
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/r/researchchemicals
Fuck nep. Absolute trash. The problem is snorting this piece of shit
I have done so many stims in my life and none left me paranoid twitching and with my entire chest hurting all around like this.
If there's anyone with first hand experience on this please let me know. Thanks in advance.
Looking for a safer alternative, please help
What the fuck was/is that? When will my sweet Beatles be back and when will my dear wife not sound like the dude from the crash dummies?!? 😂
does anyone has any anecdotal experience with aeruginascin or it’s active metabolite 4-HO-TMT. As a trimethylammonium cation, it is unlikely it crosses the BBB to produce a psychoactive effect. However, it’s still untested & i’m curious if any of you have given it a try. Also would love to hear about an experience with Inocybe aeruginascens ✌️
I have nasal spray and I hate it lol it's a 2fdck nasal spray and I just want the powder, how long should I put it in the microwave for? It's about 28ml. Or is the microwave a bad idea?
Edit: I'm open to other ideas
Are there any legal alternative stimulants ?
Do 3/4mmc have a 'threshold' dose like MDMA, where you need to hit a dose to feel good and anything below that feels bad?
If you snort for example like 20-30mg would you feel anything good? Or is there a 'threshold' you have to pass.
So after taking a 6 months break from all substances except weed, i decided to do this combo tonight. I started off with taking 1mg xanax and once it hit, i smoked a fat joint and did two lines of 4mmc. All i gotta say is that this is the most euphoric high ive ever experienced. Im so fucking geeked but at the same time calm. Lol. Wish yall a happy friday night
Hey all, Ive been interested for long now to try mapb/4fma or 2ce but to be honest Im scared/anxious of the local customs.. I live in Greece and Id like to know how safe dhl shipping from Netherlands can be.. Thanks in advance.
Will be on holiday this weekend in Amsterdam. A local friend sent me the menu of a delivery service. They list 3MMC among the offerings (of mostly non-RC drugs). I’ve never tried and am curious to give it a go. But I won’t have a chance to get it tested. What does the community think the odds are that it’s actual 3MMC?
Please delete if not allowed, and I'm happy to repost in a way that complies with the rules of this sub. I'm a journalist looking for people to tell their personal stories about research chemicals and the role these substances have played in their lives. Why you started using them, why you kept using them, why you quit or cut down if you quit or cut down, and how your use has evolved over time. At the moment I'm applying for some grants related to this topic, and I am hoping to do a series of in depth investigative stories on it—some narrative, some data driven.
I'm an experienced audio and digital journalist who has covered topics related to psychoactive substances, the war on drugs and harm reduction for years. Here are a few examples of my work. Happy to answer any and all questions. DM me if you want to chat. Thank you so much.
So yesterday me and my gf went to a club and wanted to try those 2c-ef 10mg pellets from a famous vendor.
The pellets are purple and are precut in half.
We each took half a pellet and decided to wait and see before taking the other half as we were at a club and did not want to lose it.
From reading some of the scarce trip report of 2c-ef it seemed like it could be a nice party enhancer like 2c-b is, but it did not feel like it quite frankly. It would probably be a lot of fun at an outdoor festival in the daytime.
I did not take notes so I'll just put what I remember, which is not much, down there
T +00:00 : had a few drinks beforehand, and got in the club. Then we both took half a 10mg pellet.
T +01:00 : start to feel some tinglings, as well as a slightly uncomfortable body load (slightly nauseous), making it hard to complete long sentences.
T +01:45 : definitely feeling it. Still manageable though, but tripping more than rolling for sure. Feels like melting by time. Nice geometrical and colorful CEV. Knees are a bit shaky, standing up is tiring.
T +02:00 to T + 04:00 : time is really stretching. From there on, we realise the club is not the best setting, we need a couch, not to stand up, although we found a dark corner where it's a bit quiet and we can enjoy the music without being distracted by people. But we want to wait and see before leaving the club so we stay indoor and walk around trying to find a comfortable spot. Some nice breathing OEV when looking at patterns on the wall. Still, it's manageable, probably a ++ on the shulgin scale. Some really nice introspection too, and the feeling of moving around the room through people when my eyes are closed. Headspace is a bit messy at times but not too much.
T +04:00 : decided to leave the club and start walking home. Knees are still weak but fresh air is nice. The last 10 minutes of the walk are bit tough on the knees.
T + 05:00 : finally home, have a nice warm shower that feels great, put on Jefferson airplane and then atom heart mother. In the bed is right where I want to be. Still going through some nice CEV. If looking at textures, have some slight visuals too.
T + 07:00 : I'm exhausted and want to sleep but can't fall asleep. Effects are mostly gone now, but I'm still wide awake.
T + 08:00 : finally getting close to sleeping, switching for a calm music helps a lot.
T + 10:30 : have very nice sex in the middle of a messy dream. Fall asleep again
T + 14:30 : wake up feeling the afterglow. Really nice and quiet.
All in all, it's a fun psychedelics, but definitely not for raving. If anything it is couch-locking, I would not advise thinking of it as a long duration 2c-b, even at small dosage. I would compare it more to LSD, with a clearer headspace, although this might be due to the small amount I took.
It's also very potent, and it might vary from people so I would recommend dosing low first, like 10mg in a nice and comfy setting (not a rave).
Anyone tried this compound from the no ultra experiments ??
Like the title. Some months ago (4/5) I made a nasal spray with 4-mpd, salt and distilled water. Today I saw it and noticed that it's brownish, like if it gets oxidiced. Last time I used it was like 1 month ago and worked fine! Didn't check if it was brown, maybe it was 🤣.
Should I throw it?
Hi r/researchchemicals Community,
My name is Bryant. About a year ago, turned to this community for help and to hear your experiences. Now, I’m back to share the results that you made possible.
I’ve thought a lot about how I’d come back and share this study with you all, and words don’t even capture how honored I feel to have been welcomed here. Your contributions made something very special possible, so let me show you what we’ve accomplished:
Thanks to your insights, I was able to publish two papers both in the International Journal of Mental Health & Addiction, currently the top-ranked peer-reviewed substance use journal globally. It’s incredible to think that your voices and experiences have reached such a wide audience. You can view the studies here (or feel free to email me here or on ResearchGate for a PDF copy):
Summary: Do people know when they’re at risk of addiction? Most people professionals and other people assume they don’t. My first paper flips a common assumption on its head – turns out, people do have a sense of their addiction risk :) I asked if people can accurately sense if they're on a risky path with substance use. Turns out, they can. People had a surprisingly accurate understanding of their own substance use disorder risk. This study challenges a lot of what professionals and even friends and family assume about substance use and addictions. It makes us rethink how we assess and talk about risk in healthcare and research. Essentially, it’s about trusting people’s awareness of their own experiences and recognizing that the discrepancies in substance use reporting (for example, people saying they drink 2 days a week when it is actually five) come from the consequences of use (such as losing access to a medication), not an unawareness on our part.
Summary: How does language impact stigma in addiction self-assessments? In the second paper, I looked at how language affects people’s attitudes toward addiction. Have you ever filled out a substance use self-report? I have and they do not always feel very welcoming. So, what I tested is if switching out typical “addiction” language for less stigmatizing terms changes the way the self-report measures substance uses and if it affects our beliefs or the beliefs of people filling out these measures. I found that it does not really chance what the self-report measures; However, people’s negative biases decreased, especially in groups who weren’t familiar with substance use. So, it turns out, the way professionals word things matter a lot. This study shows that small changes in wording can transform perceptions and reduce stigma, making the whole field more inclusive.
Materials & Data: As promised:
I am giving the data back to you, the people, and anyone who thinks they can use it to advance our knowledge and our cause. These data are your, so dive in, explore, and share as we advance our knowledge together. If you find new insights, I’d love to hear them.
You can find all the full study methods, materials (e.g., questionnaires), and dataset with a codebook at my Open Science Framework page. I believe that these data below to the people, and that I just looked through them to find patterns. So, feel free to share with others, and as you explore your data, if you find any interesting insights or new discoveries – I’d love to hear about them.
Please share your thoughts with me! What resonates with you? What misconceptions need addressing? What insights would you want every researcher or patient to know?
You can learn more about my mission here and at www.BryantStonePhD.com and you can email me at Contact@BryantStonePhD.com. You might also want to check out the acknowledgment sections of these papers.
Thank you all so much for making this possible :)
- Bryant
P.S., I will be sending this info to top substance use researchers, people running organizations, and other institutions around the world. What you share here has a real chance to shape their views – tell them what they need to hear.
Keep the Conversation Going:
2cbfly is so expensive and I can't get powder, even if it's my fav drug (was my first 2C-X, tried only once with 6apb, best drug experience I ever had, lasted almost 24h somehow 💀💀) id like to know how good is 2C-EF, is it visual? What about the music enhancement? Headspace? Duration/dosages
Thanks
i'm changing psych meds and have horrible side effects with NEP being the only thing keeping me somewhat functional
shitty thing is that i think it doesn't work much anymore
what's the minimum time i should take a break to help with this?
i took a 4 days break this week, but didn't feel much if a difference ugh
Recently I have been fascinated, and intrigued by the works of Alexander Shulgin and his wife Anns amazing ability to explain psychadelics and psychotherapy in words easy for the normal human to comprehend.
I have been on a consciousness journey, exploring alternate states induced by meditation, hypnosis, Tryptamines (mainly psilocybin), but I am lacking the ability to acquire most of Sasha’s work. (Examples being; 4-ho-dipt, 2c-b, 2ct7, etc…)
I have a calling to learn about consciousness and how our minds work, I am taking classes in school studying these effects and I need to study these effects using Sasha’s technique; human guinea pig..
I used to be able to get ahold of any rc analog back 2 years ago no issue, And now it’s half near impossible. What the hell
Hello all!
I have a question that I figured someone here might be smart enough to answer. I have quite a bit of 4-pro-dmt and have started filling my own cartrs with THC distillate. I'm considering mixing some of the powder into the THC oil.
Will the DMT still have psychedelic effects after being exposed to a heating element?
Should I mix it with the THC oil or just make a DMT cart? What's the best way to mix this combination? Should I just heating the distillate and add it?How can I determine the mixing ratio for a 1 granite cart?
Will putting this in a cart and smoking speed up the process. My main goal is the make the trips shorter as a 1.5 hour trip is too long for me. I'd like to have the 15 min DMT trip without buying a cart from some shady dealer
orally takes long to peak and if i can snort whats the good dosage ? i have low tolerance had it only few times orally
Just beacuse it is halloween, here is just a brief and dirty reportback on an experience I had fairly recently on a cocktail of novel dissociatives and a single 8 mg hydromorphone pill in addition to generous amounts of cannabis. This is not as detailed or useful as any of my normal reports, but I was feeling the holiday spirit and felt like writing about something that actually happened this year ;)
It is noteworthy that 2 of these compounds are completely novel dissociatives that have not been reported yet. I am working on reports on each of them singularly, I hope to have them out sometime in the coming weeks. If i had to summarize them, I would say 3-F-PCiPr doses around 30-70 mg, has a fairly short duration, and is soft, smooth, at times tranquil and other times quite uncomfortable and disorienting. PCiPr doses around 10-30 mg, has a very long duration, and is subtle at first, then very intense and all consuming, stimulating and manic and very functional but also quite heavy. Like a more lucid 3-HO-PCP. I had encountered no indication that either of these compounds had any CNS depressant activity; both elevated heart rate and didn't cause any perceivably respiratory depression (measured with a pulse oximeter), Appreciable respiraratory depression hasn't really been observed in in the non-2'-oxo substituted arylcycholexylamines (though some can be weak partial agonists of the mu-opioid receptor). Nevertheless, I determined for myself that I was comfortable with the risk, I would never recommend to anyone else that they combine novel drugs with opioids.
I had taken 20 mg of PCiPr intranasally earlier in the night, followed by 50 mg 3-F-PCiPr intranasally several hours later. I was just riding the high of a very nice first date I had had with somebody where I had cooked them dinner and hung out at my house. A short time after that, I crushed up a single 8 mg Hydromorphone pill and snorted it. I was smoking cannabis and hitting a nitrous tank throughout the rest of the evening, which was mostly spent chatting with friends and playing Dynasty Warriors 3 on the PS2. I felt floaty and warm, I was dizzy and lightheaded and spacey like I was being baked in warm static. Everything was faded and muffled in the most pleasant intoxicating way, like the empty spaces of my skull were stuffed with plush filling. There was an underlying mania and a stupefying dissociation. A warm opioid nod left me drowsy and slack jawed, gently waving back and forth in the glow of my CRT TV. I felt like seaweed being tossed about in gentle waves in a shallow sandy tropical sea, waves that swelled and rolled through my body as a warm, itchy euphoria. Everything was pleasantly bleak, everything was heavy in the silent late night twilight.
I eventually topped off with 10 more mg of PCiPr and 20 more mg of 3F-PCiPr. I was done playing video games for now, I was absentmindedly sitting in the dark browsing the internet. Every thought was a struggle, every action felt impaired and restrained in every way. I was moving and thinking in slow motion, every little task taking twice as long as it should have. The obliterating stupor of opioid bliss.
I was getting ready to go to bed (This was about now 4 hours since I had taken the initial dose of 3-F-PCiPr). I decided to smoke more. I am not sure why I made this decision- sometimes I will smoke a bit before bed to unwind, but with dissociatives still in my system, why would i think this would do anything but stir the dust again and bring them to the forefront, not conducive to sleep at all? And I didn't just smoke a little, I smoked a lot. Incidentally, this is exactly what happened. My heart was pounding, I was soon in the throes of a dissociative panic. Everything came rushing to the forefront, it was distressing and overwhelming. The world began to unravel around me. All I could hear was my heart pounding in my head. I became profoundly confused- how did I get here? Where was I? Where was my body? Why did I feel this way? Who was I? Darkness had consumed everything, I could not perceive anything around me anymore. My surroundings had fallen away to an abyss. It was as if I was suddenly an isolated consciousness caught immediately in the present, no point of reference for what came before, how i felt before, no sense of how I ought to feel in the future, just suddenly being deposited into a disorienting and confusing existence, borne from intense unfamiliar and bizarre sensations, borne from an unknowable void where sensations existed no longer. I was a very small mind, very suddenly all alone in a very large and imposing place.
And in this vulnerable, lost, confused place- I was prey. Something stalked the reaches of this dissociative abyss, something indescribable, without physical or sensory form, only perceptible as concentrated malicious intent. I could not feel my body but I could sense by blood run cold in its shadow. I was no longer protected by my grounding in our reality, I was at the mercy of something that showed me that I was past where my mind could feel intact. It pulled me away from our world as bits and pieces of myself began to come back- I was now cognizant of what I was, and what was being lost as my previous existence had began to decay into illusion-it was this sense that I had broken out, that i had hacked my way out of our reality into this alternate one, where I was lost and afraid and vulnerable. That the existence I had known was an illusion to insulate me from the horrors of this world where entities preyed on stray consciousnesses and spirited them away to parts unknown. And so it was that my entire life, that every entire life, all life times, all humanity, was withered away to nothing, inconsequential and forgettable in the scope of this new void, greater than anything I could perceive, both endless and final, all-consuming, dominant, and utterly inescapable. Where darkness ate at the borders of my perception and shadows stalked through whatever could be perceived as apart of the inky void. It was cold, impersonal, and unfeeling as anything could be- even the emptiest plane and bleakest space on our world is still a physical realm, I still have the company of the sky and the earth- here is nothing, the bitter loneliness of knowing that not only is nothing here, nothing could possibly be here, nothing has ever been here, nothing will ever be here, nothing but my tormentor who has placed me here, who is so vast and powerful that I am borne the terrible loneliness of its indifference, that I am so powerless to be imperceptible to it. How can I beg for mercy from something that only perceived me for an instant to lock me in its limbo, to whom I am a speck of dust lost among a million specks of dust in a million empty spaces? It was the dread of being abandoned, forgotten, truly deeply dissociated from everything I had ever known and will know, and from all that had ever known and will know me. It was the greatest sense that escape was impossible that I have ever known.
All of my life, all of my memories, everything I was, everything I had known, was fading away into a distant memory. My fate was to be here, still, cold, perceiving only dimness for an eternity that had already begun to pass. The light of existence and experience was being weighed against an ever-extending final ultimate void that only grew to dwarf it, averaging out to an increasingly grey and stagnant life. This was it, this was all it would ever be.
Then snap, it was over. It was as though this tormentor had noticed me, had decided I was to be freed. All of a sudden, I just came to in my room, like nothing had happened at all. A moment of mercy. I had not just come out of it, I had snapped completely back into reality, I was fully lucid and sober. I had only seen how much time had passed- less than an hour- but it had felt like an eternity. I was so confused and disoriented. How did it just stop like that? I laughed out of sheer relief that it was over. I sat with a terrible nausea that only developed more as night turned into morning, culminating in me repeatedly vomiting and barely being able to keep water down for much of the day. Some terrible psychosomatic reaction maybe, or some adverse reaction to the opioid as I don't use them often. I really thought I had finally broken reality. I was grateful to be released from this void.
I have to use low doses of fluoxetine for not being a unfocused mess crying for no reason.
Looking to find something to go on a little binge while I'm out of town next week. What is the closest thing to 4-MMC, or 3-MMC that's clean? I want the super euphoric stimulant high with a clean come down.
Hello guys, long story short im addicted to benzos. How did it happen? Last year I had a tragic event in my life and I depended on Bromazolam and Flubromazepam to keep it together. I tried to taper it, taking only 4mg of Flubromazepam/week but somehow I end up also taking 1 or 2 mg Bromazolam. I need to chill the f down cause now I can’t control my emotions and I’m very dependent on the substance to calm myself down. Any advice on this shitty situation? I’m afraid to just stop taking it cause I have such bad muscle spasms I’m afraid I will have a seizure.
Last week I took LSD (1P-LSD 150mcg Art Blotters), first time and to much. So I used 3 mg of bromazolam, try to kalm my head. This was Monday. That's the last I remember. The other half I know bc people told me. So apparently I woke up on 6:30 (smartwatch) on Tuesday and took 33 mg of bromazolam, don't know why but apparently did. Had many missed calls and texts because I slept. My family was concerned and my mother came to visit later on the day. She told me she ringed my door like 10 times and then walked in with her spare key. It took her 30 minutes to wake me up. She called the doctor and the ambulance came. The doctor said my mother had to stay to keep an eye on me. I wasn't allowed to sleep longer than 2 hours, and if I cought or almost vomited my mother had to wake me. Wednesday my mother made me a list, things I had to do at that time. Like eat, shower, feed the cat and just the basic stuff. Because my brain didn't work. I slept most of the day. Thursday I made my own list for the day. Friday I start having memories again, that is the first thing I remember.
My brain is doing much better than last week, but I have problems finding words. Also when I'm in a conversation it happened that my head went blank and I just completely forgot the subject or what someone was saying.
I also quit smoking week (smoked everyday before bed) since 3 days now. So one week later.
Now I feel horrible, I don't know if it's still from the pills or that It also might be the weed. I don't know what to do because all I want is to start using something again to numb this.
Will my brain gets better and will this all pass?
Have any of you also developed neuropathic symptoms after NEP - or any other cathinone/stim?
I have been walking around with terrible nerve pain for 2 weeks, especially in my hands, forearm, elbows. Sometimes it is better for a while, but sometimes it is unbearable.
I have an appointment with the neurologist next week.
I would love to hear from you guys.
The main question remains, will these symptoms go away, or will they stay?
I have used in 1 week, 1gr NEP, drank alcohol, benzos for sleeping.
When I woke up I noticed that my little fingers were numb and I had tingling. That pinking was resolved immediately, that tingling remained.
"UPDATE: A STRONG DOSE IS ABOUT 10MG! I DID 15, IM GOOD BUT VERY OUT OF IT! To be honest its good, but the taste and smell make me want to throw up still after 10 minutes I can still smell it just as strong. Gonna capsule the final 2 doses I have of it When I will." I used to do it nasally but I wont snort anything anymore. Last time I vaped O-PCE I overshot the dose, was tripping my balls off and couldnt even walk as my legs felt like wood logs. How much mg should I vape, and do I have to preheat it or etc like not puffing untill melting. Thanks in advance guys!
I use a dab rig with a customized oil burner, not foil or e-vape.
UPDATE: So i Just vaped 15 mg like any other crystal in my dab rig, ITs a sweet spot, WOuldnt do any more! Now I got that "disso crack" feeling. Last time i probably did double this dose..
Update: If you decide to vape some O-PCE put this on!ł<; https://www.youtube.com/watch?v=Zs46ZBbgzJg
As there is basically no info about this very healthy drug i decided to get a gram of it, which was a bit of an impulse buy but hey, tried it now.
It's honestly pretty good but i'm probably not doing it again, it's extremely reminiscent of 3-MMC but maybe a bit more potent. Doses are a bit screwed because of tolerance from last weekend but it was stronger than i expected.
Possibly more serotonin than 3MMC, can't compare it with 4cmc or 4mmc as i haven't tried them yet.
Duration is about these same as 3mmc/3cmc
Good drug, but with the structural resemblence to 4-BMA and 4CMA it's best to stay away, though i am skeptical of the fact that 4cmc is actually as neurotoxic as people make it out to be, but all cathinones are to an extent so yea. But worst case(if it somehow is as neurotoxic as 4-BA, my serotonin will be fucked for a week as the depletion of brain 5-hydroxyindoles lasted for at least a week with 4-BA(https://www.sciencedirect.com/science/article/abs/pii/0028390875900994?via%3Dihub), but so far haven't noticed anything out of the ordinary)
24h update, feel completely normal absolutely no issues