/r/estrogel

Photograph via snooOG

Safely and cheaply creating feminizing, masculinizing and custom transdermal gels and sprays at home, for ALL those in need - menopausal women, trans women, men who want a soft skin, bio hackers, enbies, trans men, men with low-T, etc.

We started with estradiol gel, but now have plenty of info that is applicable to all transdermal treatments. This is guerrilla healthcare, so please use this info safely and wisely, and always know what you're putting in your body.

Everyone is welcome here!

Creating transdermal gels and sprays at home, for ALL those in need - menopausal women, trans women, men who want a soft skin, bio hackers, enbies, trans men, men with low-T, etc. Check our FAQ for an introduction to homebrewed transdermals and our wiki for vast amounts of information, research, and recipes.

Safety first!

We believe gels applied to the skin are inherently safer than injecting, and when making HRT yourself safety is paramount. Maintaining safety outside a professional laboratory is difficult and should be designed to be fail safe. Screw it up and what might seriously harm you to inject is more far more likely to be safe on the skin.

Safety in never having to worry about getting cut off from your treatment because you can't afford it, your doctor retires, or there's supply chain problems. A few hundred dollars will buy you a 50+ years supply of estrogen for HRT.

Safety in being able to use what you need instead of relying on out of date medical practitioners. Our high strength gels have the same potency as injections, and you can adjust formulations as needed.

And that's just the start of our guerilla healthcare!

Other resources?

Discussions on unusual steroids and their sides effects (Tamoxifen, Anastrozole, Nandrolone) happens more on /r/steroids, and discussion on experimental treatments is found on /r/peptides or /r/Biohackers

General discussions on how to acquire commercially-made medicines happens more frequently on /r/TransDIY

Censored national subs

Talking about DIY on some subs will get you in trouble: their headmods care more about themselves and their own legal risk than they care about you or the risks that comes with delayed transition or gatekeeping, so be very careful on:

If discussions about DIY are not allowed in your national sub, please create a new sub, tell us and we will link it here: in the meantime, or even later, feel free to post here in any language you want. Following the "everybody is welcome" policy, you do not have to use English here on /r/estrogel.

Censorship-free national subs

This is a list of alternative national subs that don't censor talking DIY:

  • PT and BR: /r/TransBrasil : all discussions are possible -- including about DIY and grey market pharmacies!

/r/estrogel

10,146 Subscribers

8

How long would 100g estradiol powder last?

I have 100g of raw powder and trying to decide if I need to source more - how long would this last, roughly speaking?

7 Comments
2024/12/04
23:56 UTC

0

Isopropyl alcohol vs food grade ethanol (96%)

Hi, I am interested in replicating the "TeaHRT" recipe to make Estradiol spray but I see that it uses Isopropyl alcohol instead of Ethanol.

I would prefer to use Ethanol 96% because:

  • Ethanol, unlike isopropyl alcohol, is edible.
  • I have a source of 96% Ethanol that is essentially "free and unlimited" (my parents distill ethanol professionally)

Will using 96% food grade Ethanol cause problems compared to using chemical/pharmaceutical grade Ethanol >99%? For the TeaHRT recipe can I simply replace the isopropyl alcohol with 96% ethanol?

TeaHRT's recipe:

  • 600mg estradiol powder
  • 13.5mL isopropyl alcohol, replace with 13.5ml 96% ethanol?
  • 13.5mL isopropyl myristate
  • 3mL polysorbate 80
0 Comments
2024/12/04
23:44 UTC

67

PSA For All: See the New Provisional Rule 7 - No discussion of primary estradiol vendors

We are now attracting the eyes of the world. Be it tyrants, publicity, or simple bigots with too much time on their hands. It is an inexcusable risk to publically share the biotech companies the DIY HRT ecosystem relies on. From now on, name dropping direct producers of estradiol (primary vendors) is strictly prohibited. Repeat offenders will suffer consequences. Secondary vendors who resell estradiol bought off biotech companies may be discussed openly, albeit with caution.

Me and the moderators have been discussing this for a while. And for far longer, I've had folks requesting I instate a rule such as provisional rule 7. Recently someone (who shall remain unnamed) I highly respect contacted me about this, and put forth some really good points. Essentially, to publically share primary vendors endangers the entire DIY HRT ecosystem. Public corporations are at the mercy of governments and bigots alike. Anyone dedicated enough could uproot the entire DIY HRT ecosystem. I'm consulting another esteemed member of The DIY HRT community, asking for their take on the situation. See a transcription of the email I sent them for some further context:

Hello [Redacted], I hope you're doing well.

I am u/Juno_the_Camel, a moderator on r/estrogel. I need your advice on a dillema. Presently, we allow unrestricted discussion of estradiol vendors and sources. Folks can ask about, discuss, and share estradiol vendors freely. This includes the biotech companies supporting the entire DIY HRT community. Estrogens and progestogens are not controlled substances under US (and most other country's) laws, so in this we don't violate the law. But, by having these biotech companies be public knowledge, the entire DIY HRT community is endangered.

Biotech companies are very weak to pressure. Be it pressure from governments, or the public. If the biotech companies that supply the entire DIY HRT community's are shared publically, we're at the mercy of the world. It only takes one tyrant (Donald Trump, Ji Jing Ping, etc) to ruin us at a whim. Even simple bigots (like those over on [Redacted are able to ruin our supply chains. (I suspect they contributed to Hubei Vanz's recent policy change) (They're likely the folks who spam and DDOSing homebrewer websites).

Logically it makes sense to restrict discussion of estradiol vendors on r/estrogel. But I'm very conflicted. The entire point of r/estrogel is to make HRT universally accessible. Even for those living in poverty, or under tyrants. To restrict discussion of pharmaceutical vendors is to turn out backs on the founding tenets of r/estrogel itself. In truth, I don't know if I have it in me to withhold information that can make or break lives.

And yet, if we don't restrict discussion of sources, we endanger the entire DIY HRT ecosystem. It breaks my heart to do this, but I truly believe we'll need to ban discussion of estradiol vendors on r/estrogel. Is there anything I'm not considering? Do you see anything I don't? I'd love to hear your thoughts on this.

Discussion is still ongoing, but in the meantime I think it prudent to instate provisional rule 7. It will likely undergo changes in the near future, but in the meantime, please observe rule 7 - and report folks publically sharing primary vendors.

Additionally note, discussion of secondary vendors (who resell estradiol) such as Purple Panda Labs, Dragon Ordnance, Allie, and Water Lily is still permitted.

I am sorry everyone, it breaks my heart to do this to you - especially to the newcomers here. And I'm sorry u/Darthemofan, I hate to go back on the founding tenets of r/estrogel. But I truly don't see any other viable path forward.

Best of luck everyone - u/Juno_the_Camel

Edit: One (of many) examples of our recent publicity - https://archive.is/cJuuC

10 Comments
2024/12/04
23:31 UTC

112

The Guardian just name dropped and put a direct link to this subreddit

As the title says, The Guardian put out an article today which put direct links to the most recent mod post with all the info on suppliers AND the personal reddit account of one of our biggest homebrewers. We need to do something because in the next couple months, another article like this is gonna be bad news for DIY as a whole.

Archive link to the article so that it doesn't drive The Guardian's metrics up: https://archive.is/cJuuC

17 Comments
2024/12/04
22:56 UTC

7

has anyone had a positive experience buying from purple panda?

looking to buy 2 lifetime supplies of cas 50-28-2 from them and i wanted to know if they are a reputable seller.

i’m also confused by their quantities for buying. is one quantity a gram?

9 Comments
2024/12/04
02:48 UTC

3

dose question

hello everyone! i've been doing 3 months now of hrt and i had a massive question specially since i recently moved from gel to dropper and i remember reading a lot about dividing the dose to do half every 12 hours, but most of it was because of how long the gel took to dry- so my question was if i still had to do that 👉👈 thank yall so much for reading!!!

5 Comments
2024/12/04
02:13 UTC

0

Potential scammer active in Trans DIY subs

Hello, I’m not sure if this is allowed but I have had DMs with another member of this sub and now I’m very concerned that they may be preying on desperate trans people.

Be wary of User: dogtime180. They’ve been active in comments here and in the bigger TransDIY sub.

Here’s my proof (mods especially please view this for yourselves and tell me if I should remove this part specifically):

https://imgur.com/a/suspected-scammer-promoting-scam-source-O1n6yFi

They’re all screenshots of me doing just some light digging into a source they recommended me.

9 Comments
2024/12/03
18:47 UTC

22

Areas of body ranked by absorption?

Its often said the scrotum is #1 ranked for best absorbtion for estrogen gel, but which body parts are 2nd best, 3rd best etc?

9 Comments
2024/12/03
12:24 UTC

17

did my first injection today!

think i did it right but the anxiety is always there, i injected into the middle outer third of my thigh (IM) if i did it wrong, what are the consequences?

5 Comments
2024/12/03
00:57 UTC

3

Link for Water Lilly pharmacy

I had my link to their Estradiol stored on my computer. I clicked on it this morning and it said “page no longer available.”

Can someone provide the link so I can order their raw estradiol. Thanks!!

3 Comments
2024/12/02
20:57 UTC

7

Alternatives for Hubei Vanz

ISO alternatives for hubei vanz. Who knows the water lily site? Reliable suppliers on MIC?

15 Comments
2024/12/02
15:13 UTC

7

Vaginal estrogen

I am traveling on a 4 month cruise. I ran out of my vaginal estrogen. I use estradiol cyp injections from Teahrt. Does anyone know if I used a little of it on my vagina if it would absorb? Or would I be wasting it?

2 Comments
2024/12/02
08:44 UTC

15

Stickies for other medication

(probably the wrong place to ask, but its the place we know)

Seing as stickies (estradiol pills combined with guar gum) are slow release, would that also work for other medication like ADHD meds?

The thing is, swallowing pills just dosnt work for us. We only manage to do it when its an extremely small one and even then it causes trouble. So the thought was that if the sticky method uses pills and makes a slow release out of them, that we could make stickies out of the ADHD pills, and keep the extended release

Maybe there's a thinking error or something, so thought we'd ask here first, before trying it

12 Comments
2024/12/02
00:25 UTC

8

RAW testosterone

Hello everybody!

I’m a bit new with the whole thing but I would really like to make my Testosterone gel as my country is trying to make us have no access to HRT. I just have a couple questions.

The recipes say testosterone but I’m not sure at all about what testosterone I should use. The source I found has many powders:

-Testosterone Undecanoate

  • Testosterone Blend (Sustanon, sus 250)

-Testosterone Phenylpropionate -Testosterone Cypionate -Testosterone Enathate -Testosterone Decanoate -Testosterone Propionate -Testosterone base micronized -Testosterone Base (Testosterone Suspension, TB)

Other than that I haven’t found any information about the shelf life of the powder which is needed for the gel and the gel itself. I’d really appreciate some information about that.

Also I’m not sure how safe ordering raw testosterone to the EU is.

I’d really appreciate your help 🙏

7 Comments
2024/11/30
18:13 UTC

7

any advice for storing 17b estradiol?

How should I keep it stored? I was thinking an airless jar kept in the fridge or cold closet.

8 Comments
2024/11/30
17:34 UTC

1

re: Compunding Powers' hair serum at home - an alternative to propylene glycol?

Hi, not long ago I made a post about compounding my own hair serum in a similair fashion to Powers, but since it's hard for me to get raw I'd used crushed pills and then filter out any residue.

Powers uses a 45% propylene glycol, 40% ethyl alcohol as the base, but I'm pretty sure I'm allergic to propylene glycol, as I get pretty bad dandruff when using topical minoxidil that has it. It's my understanding that the ingredients bind to the alcohol anyway, so could I substitute the propylene glycol for something else, or maybe even make this into a gel or cream?

My ingredients per 100ml of liquid serum:
500mg bica
1g biotin
300mg melationin
1g azelaic acid
5g metformin
50mg finasteride
0.5ml tea tree oil
0.5ml rosemary oil

So maybe I could mix them into ethyl alcohol at the highest concentration, and then mix that into an aloe vera gel or something? I'm a total rookie, so I have no clue how to do this stuff, I'm really seeking advice here.

8 Comments
2024/11/30
14:20 UTC

3

151/3 Proof Ethanol for Sprays?

Hi, seeing information that might not be the most clear, but wondering if using a 153 proof/76.5% grain alcohol would be sufficient for making an estradiol spray? Or would I want to look for a higher percentage of denatured alcohol or IPA

5 Comments
2024/11/30
02:03 UTC

17

has anyone bought from hubei vanz since they changed their policy?

i’m looking to buy a kilogram from them. i got in contact with them and they are requesting a direct wire transfer for the products payment.

is this their new standard for purchasing their raws, or am i about to be scammed out of 1k?

i’m trying to prep for me and my little community, so im willing to purchase that much from them.

11 Comments
2024/11/30
01:22 UTC

10

Buying with crypto

Could someone post a link (or links) with info how to make online purchases with bitcoin or direct me to the type of institution that could get me set up to do so? I'm a complete newbie at this. Thank you.

13 Comments
2024/11/29
18:49 UTC

5

Can't wait to start

Transdermal estradiol using airless pump bottle for precision dosage, each pump expels 0.20ml, or 2mg. (4 times more E2 than a single pump of Oestrogel).
if used 4mg/day 2pumps/day each bottle lasts for 4 months and half.

Is the above accurate?

Gynokadin Dosiergel (Estradiol) - 0.6mg/g (80g)

Have ordered both of these, waiting on them to arrive. Is one recommended over the other? Anything I might expect switching after one runs out? Which one would you use first? Dosage recommendation of Gynokadin?

1 Comment
2024/11/29
16:49 UTC

45

Synthesis of Estrogen

Ive been looking for any sources showing how to manufacture estradiol from commonly available items such as chicken eggs and yams, but have only ever just heard of such processes as rumors. Does anyone with a chemistry degree have an answer to how one would go about synthesizing this chemical compound, or is it not FOR us mere mortals to know.

It seems like china might not be our best answer in terms of how to source, so the question then becomes, how can we manufacture it ourselves in the US?

13 Comments
2024/11/29
16:34 UTC

6

Gel question

I’m considering making my own gel for DIY monotherapy. Can anybody tell me what the difference is between the following and what is recommended?

Beta-17 Estradiol

Estradiol Enanthate

Estradiol Valerate

Estradiol Undecylate

6 Comments
2024/11/29
13:16 UTC

10

I have been preparing for DIYing some estrogel in future. Is there any equipment I am missing?

Jewelry Scale

INSTALAB magnetic stirrer

Kitchen scale

XSmall Mylar bags

Silicone hydrogen absorbers

200ml beaker

Lab spatulas

Nitrile gloves

2ltr beaker

Weighing boats

Vacuum sealer bags (small)

Vacuum sealer

Airless pump bottles x 8

Milk frother

10 Comments
2024/11/29
09:28 UTC

0

Clarification from Hubei Vanz

I recently found this discussion with a Hubei Vanz salesperson which explains why they no longer provide for small orders. Their response was the following:

"With the increasingly strict regulation of pharmaceuticals of China, the company decide to change the policy as inappropriate using of the product may lead to many potential health risks and problems.

Our company want a health development so that we can service our customers for long years, please kindly understand."

Many of the sources on made-in-china will most likely respond in the same way due to the stricter regulations, but perhaps other producers also located in the Wuhan area such as redacted, that seem to care less for regulation (can't go into detail due to a certain rule but check out their products) could still be considered for small orders.

Edit: In light of TeaHRT's latest post, I redacted the name of the potential source I suggested and if you'd like to know who they were feel free to dm me. However, I cannot recommend this source since I've not heard any purchasing testimonies from them. If this edit isn't enough, just let me know and I can make any other necessary changes~! ❤🌸

Edit 2: Wait... what happened to TeaHRT's post??

11 Comments
2024/11/28
17:56 UTC

24

thinking of making a google sheet for mic sellers? thoughts?

Like the title said i am thinking of making a google sheet to list sellers on mic and there trustworthyness/prices/ect obviously i will not just be giving the link out left and right and it will be a discreet affair for those who need it. like rule 6 states going into detail on stuff like shipping methods and seller info will be forbidden and stuff like 'discreet' will be a simple y/n answer but do you guys think its a good idea or a dumb idea which would easily get sellers taken down? i personnaly think if executed correctly and lowkey enough could work.

14 Comments
2024/11/28
01:16 UTC

90

Outside communication if/when this shuts down.

Is there a sister group on telegram/signal for this group of diy hrt? I imagine reddit isn't in love with the idea of discussing this topic, and I'm wondering if there's any off-site channels where these discussions can be had? If not, would it be possible to get one up and running?

39 Comments
2024/11/27
15:45 UTC

6

Debit card working ?

Does anybody know if waterlily pharmacist has their debit cards working again ?

2 Comments
2024/11/27
03:57 UTC

15

In general, when home brewing from estradiol powder, is a gel or an injectable more efficient in terms of overall estradiol usage?

I’m currently on estradiol valerate injections, and I’m considering stocking up on raw powder for emergency purposes. Which method do you find lasts longer, assuming the same amount of powder?

I know it’s not exactly the same since gels are daily and made from raw powder, while injections are weekly(or 3-5 daily depending on your dosage) and use estradiol esters. And the brewing process for injections is presumably more complex. But in general, what do you find is more efficient? And how does shelf stability compare between the two?

25 Comments
2024/11/26
14:16 UTC

2

Shelf life of E valerate

Does anyone know how long after the expiration date on a vial that e valerate is still good? The vial hasn't been opened.

4 Comments
2024/11/26
13:48 UTC

28

Another question for everyone here: What is big pharma's obsession with synthetic sex hormone analogues?

What is big pharma's obsession with synthetic sex hormone analogues? Yk, premarin, ethinylestradiol, provera, methyltestosterone, medroxyprogesterone, etc?

Why are they used in so many endocrine applications? Bio-identical sex hormones are like, objectively safer and better for humans. I swear, the more I read about synthetic sex hormone analogues, the more I'm horrified. Nasty, nasty things. Why in the world does big pharma routinely use/prescribe them over bio-identical sex hormones???

16 Comments
2024/11/26
11:02 UTC

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