/r/Biohackers

Photograph via snooOG

Welcome to r/Biohackers. This community is designed for individuals interested in DIY biology, sometimes referred to as biohacking. It focuses on DIY biology, Pharmacology, and Grinding techniques. Members can collaborate, share knowledge, and explore topics such as genetic engineering, experimental pharmacology, life extension, longevity, and bio-enhancement. This space encourages scientific inquiry and practical experimentation in accessible, hands-on ways.

Recommended Books:

  • The Awakened Ape: A Biohacker's Guide to Evolutionary Fitness, Natural Ecstasy, and Stress-Free Living

  • American Biohacker

  • Biohackers: The Politics of Open Science

Link

Sites that may be of interest:

/r/Biohackers

307,479 Subscribers

1

What's your sleep stack?

I've been using Naked Sleep capsules for a month and like them. Going to start taking my reishi and magnesium before bed too. Any other supps I should look into as a bedtime routine?

4 Comments
2024/12/05
15:16 UTC

0

What did you blokes & blokettes buy on Black Friday/cyber Monday ?

What did you buy for your biohacking needs and how much did you spend?

5 Comments
2024/12/05
15:02 UTC

1 Comment
2024/12/05
13:31 UTC

0

Thoughts on filling a nasal spray bottle with freezing icy cold distilled water? To use as a nasal decongestant.

Would this be effective? Would it cause rebound congestion? Icy cold water would be a vasoconstrictor when sprayed inside the nose.

19 Comments
2024/12/05
13:29 UTC

1

Truvaga

If you haven’t heard of such a thing, a home use vagus nerve stimulator. Calmness, sleep, mental clarity and persistent digestive issues. This is not my attempt to review, I don’t have one. What do you think?

https://www.truvaga.com/truvaga/

2 Comments
2024/12/05
13:27 UTC

2

Energy drink question

Every energy drink I see out there has tons of random chemicals and vitamins, most of which you end up peeing out. Also they have a lot of a lot of nasty natural and artificial flavors/sweetners.

I’m interested in trying to make my own energy drink which would simply be a sparkling fruit juice with a green tea extract for caffeine (maybe 100-150mg worth) in it. I might need to put citric acid as well for a preservative. But really go for the lowest amount of ingredients possible, hopefully just get away with 3.

It’s something that I personally would like to drink if it ended up tasting good as an afternoon pick me up with the sugars from the fruits and caffeine mixed together.

I’m curious if something like that would interest anyone else here?

14 Comments
2024/12/05
13:13 UTC

6

Tips for Avoiding Endocrine Disruptors pls?

Hi everyone what tips do you have for avoiding Endocrine Disruptors?

Some stuff I do:

  • Avoid Plastic (eat out of glass and ceramic)
  • avoid non stick coating
  • only wear cotton and wool clothing
  • recently stopped drinking bottled water and got a refillable glass bottle

If anyone has any other tips that aren’t obvious pls let me know! Thank you!

19 Comments
2024/12/05
12:55 UTC

94

Studies show Alzheimer's and dementia patients show signs of the diseases 15-20 years before being diagnosed. How would one treat these early signs?

As stated in the title, there are studies that brain diseases like Alzheimer's are detectable much earlier than than their initial symptoms, sometimes by as much as 20 years. Here's one.
What would you take to treat these early signs of the disease - let's assume no official diagnosis so only over-the-counter drugs or supplements.

49 Comments
2024/12/05
11:44 UTC

0

Why do breathing biohacks??

Hi,

I just wanted to know why did anyone here start doing breathing biohacks/how it helped?

9 Comments
2024/12/05
10:42 UTC

61

I think I regret quitting caffeine for 3 years

I used to drink a LOT of cola (some days even a full 1.5 liter bottle). And I also drank a lot of tea. Eventually I quit soda because it was unhealthy but I kept drinking tea. I learned about how caffeine supposedly had bad side effects so I quit.

I still feel terrible since I quit and somehow for 3 years I've gaslit myself into thinking that this is good for me. I don't get stuff done. And I feel tired all day. I can't be in withdrawal since it's been 3 years. And I don't know how I've been delusional for so long believing that this is somehow good for me.

One good side effect that I had is that I don't have constant thoughts 24/7. My mind used to be racing all the time with constant thoughts, but that's basically it. I'm not more productive, energetic, I don't sleep better etc.

I actually sleep worse and I'm less energetic. I might just edit this post after I have my first cup of tea after 3 years and update y'all.

92 Comments
2024/12/05
08:52 UTC

1

Med school supplements

Hi i'm getting super fatigued with med school with lots of muscle aches, headaches, brain fog etc. My diet is good but what can I add to energise myself, reduce cortisol, tension etc

5 Comments
2024/12/05
08:27 UTC

8

Why not olives instead of evoo?

Getting good quality extra virgin olive oil can be tricky. I was wondering if store bough olives (that are cured in vinegar) can be an alternative. Does the curing mess up the beneficial components of the olive?

25 Comments
2024/12/05
08:21 UTC

11

Ginseng reducing my depression & anxiety

It‘s day 2 (!) of taking Panax Ginseng (500mg extract, of which 100mg are ginsenosides). I started with the belief it will be not working just as everything else I tried, just wanted to use it as I paid it and it was laying around too long, expiring soon. But strangely the last 2 days I experienced a big very significant relief in my symptoms of my diagnosed depression and anxiety. I have also taken modafinil from modafinia though.

AS it‘s ONLY DAY 2 and very very common for people to placebo after starting some supplement and then be claiming really early that this works wonders and cures diseases after just starting, I just want to ask you guys about

your experiences with ginseng (similar?) and knowledge about its psycho-pharmacological properties that might be influential and affecting mental health, depression and/or anxiety (to the level or type that I noticed now). First day, yesterday, hour or so after I took the first Ginseng capsule, I noticed my depression (low unstable mood, anhedonia, lack of drive, negative thought/spirals etc.) and anxiety (generalized, social anxiety) was suddenly much much better. Like a lot.

Mood is stable and good, positive. Anxiety is away. I can get out of bed again, go into public and out of my apartment again, I answer call/ and do calls again, I shower and brush my teeth again, I move, I don‘t lay in bed all day anymore, I make myself something to eat and eat more again, I find pleasure in these things and others and have a better outlook again, my thoughts are way more positive, I have a lot of more energy in comparison (also physical - before I was almost wheelchair level regarding my physical energy and movement a day, not trying to exaggerate, before even moving a finger was like oh man this is kinda exhausting). I also have a better focus again and can think clearer, remember stuff and feel way less brain fog.

Today, second time I took it, is the same.

Of course I would come back after prolonged trial of this and post about my experience if it really works and gets clearer that I really experience this insane symptom reduction of Ginseng.

6 Comments
2024/12/05
07:39 UTC

2

NADs and NMN thoughts?

Been considering taking either NAD shots or NMN supplements but want more info. What are your thoughts? Pro? Con? Why? What would one expect with an addition like this?

5 Comments
2024/12/05
06:18 UTC

9

Longevity / Alzheimer's doctors in Singapore, Kuala Lumpur, Bangkok and South East Asia

Hi,

I recently discovered that I was a ApoE e4/e4 carrier (this is what gives 15x more risk to develop Alzheimer's) and I have been looking for a doctor to support me in fighting the gene.

Doctors I have spoken to are all more or less telling me to wait until I get diagnosed with Alzheimer's disease, because they can't do much before. But this would be way too late.

Obviously "preventive" methods exists and I'd like a doctor who can help me do all the blood tests and prescribe medication when necessary (e.g. statins and so on)

I am already on a protocol I built covering diet, sports, cognitive training, removing bad habits and sleep, (if you are also ApoE4, I am happy to share more)
but I can only do so much without someone to help me fine tune everything with blood tests + medications and see if there is any blind spots I havent covered.

Any recommendations would be great. As I am living in Singapore, I can travel to Kuala Lumpur or Bangkok quite easily for lower costs of treatments.

Thank you for your help!

6 Comments
2024/12/05
05:42 UTC

2

Torned muscle

I just torned a muscle in the groin area of my right leg. What peptides do you recommend to speed the healing?

1 Comment
2024/12/05
04:59 UTC

0

Metformin raising blood glucose

I (49F) recently started hgh (Saizen 0.2mg daily) and liraglutide (Saxenda 0.6mg daily). The hgh is part of my hormone replacement therapy for menopause (also taking estrogen, progesterone, testosterone and DHEA), as my blood panel revealed very low hormone levels across the board, and the Saxenda, I'm basically doing a version of microdosing a GLP-1 agonist. Because hgh can cause insulin resistance, I added the low dose of Saxenda to counter this. This Saizen+Saxenda combo lowered my blood glucose in every state - at fasting, at waking, during cardio and post-prandial. The glucose spikes I used to get when eating or exercising dampened significantly. I wear a CGM and monitor my blood glucose very closely.

Four days ago, I added in metformin as an experiment. I thought maybe it would work synergistically with the Saxenda to yield additional benefits in terms of insulin sensitivity and reducing systemic inflammation, but to my horror, I have found that it has raised my blood glucose levels consistently across the board. My waking and fasting glucose levels are higher, and I also get higher spikes when exercising or eating. It's negated all the benefits I was seeing from Saizen+Saxenda - my blood glucose levels are now back to where they were before I started Saizen+Saxenda. I am confused. I thought metformin lowered blood sugar, so why is it having the opposite effect on me? Has anyone else experienced anything like this?

5 Comments
2024/12/05
04:33 UTC

1

Can Vibration or Cold Exposure to the Wrist Increase Parasympathetic Activity?

1 Comment
2024/12/05
03:19 UTC

1

Ways to mitigate withdrawal from finasteride + optimize hormones

(20M) Classic story so I won’t go into too much detail. About 2-3 months into taking finasteride I completely crashed all of a sudden. I had progressively developed symptoms but ignored them under the auspices that they’d go away. Terrible depression, derealization, insomnia, changes in fat distribution, and most of all complete ED and loss of libido/sensitivity. It’s been about a month since stopping and thankfully most things have massively improved. My libido and erections aren’t the same of course, but it is improving. My remaining concern however is a total lack of sensitivity and muted orgasms. I quite literally cannot feel anything when in contact, nor do I feel anything when I orgasm. I can ejaculate and get/stay hard, but total lack of sensitivity. This is the only symptom that has not improved in the slightest (in fact, I had greater sensitivity before stopping). Am I screwed? Is there anything I can take to maximize libido and regain sensitivity? I miss being ravenous and insatiably horny lol.

Also, unrelated but prior to starting FIN I had some issues with being very lean/low body fat, which I presume may have actually been more of the cause of the hair loss initially. All this is to say that I imagine my hormones are horrible right now. Any suggestions on things to take to optimize them, like Test and rebalance them?

Would appreciate any help. I miss sex.

9 Comments
2024/12/05
03:02 UTC

1

Hip issues

I am looking for additional advice/experiences with hip issues.

I have had pain in my hip for the last couple years which my orthopedist suspects is a labral tear. I have an MRI scheduled to confirm but have been trying to find all the ways I can improve/manage/reduce worsening symptoms. An X-ray also showed I have slight arthritis and a bone spur (I assume the result of whatever's been going on that I couldn't prioritize dealing with. I'm only 42 so I would like to have mobility for a long time. I hope I can run/play sports again, but prognosis is unclear.

So far I worked with a prenatal/postnatal chiropractor because the pain started while I was pregnant, I did physical therapy, and I currently take collagen, a glucosamine/curcumin supplement, calcium, lysine, and iron because I'm always a little low. I do my best to keep up with the routine I was given at physical therapy but I don't always have time. The orthopedist said they'd give me a cortisone shot after the MRI assuming they aren't wrong about what we are expecting to see. From what I've heard, surgery often doesn't have much better outcomes than conservative management. I've read a little about PRP and stem cell shots but people seem a little split on that and whether it's worth it or not. A friend also lent me a sacral band she used to manage her pain so I've been trying that.

So far it's manageable but definitely not better.

Anyone else been through something similar? Tried some of the injections? Have good ideas? Anything I haven't tried?

8 Comments
2024/12/05
02:55 UTC

8

GI health test

So, I’ve decided to change my GI habits to see if I can reverse my food addiction. I am doing this by supplementing 30 g of psyllium husk twice daily. Each shake is combined with 50 g of whey protein. And is followed by 16 ounces of water to ensure adequate fluid for the psyllium husk. I am also taking a concentrated probiotic. I am reducing my calories to under 2000 a day.

So far I have been able to fight my hunger cravings a bit better than normal.

Does anyone have experience with psyllium husk?

7 Comments
2024/12/05
02:45 UTC

4

Doing a meetup/group in NYC for general self-improvement and growth-minded folks. Not solely related to biohacking but it's something I'm interested in, I peruse this sub a lot, and biohacking is a means to such ends, so thought maybe locals here would be interested. Apologies if extraneous.

1 Comment
2024/12/05
02:07 UTC

37

What's your nightly routine look like for bed?

What is your nightly routine look like for bed including supplements or any other herbs you take?

99 Comments
2024/12/05
01:55 UTC

3

Hormone balance post IUD

How to quickest support hormonal regulation post and iud removal? Had one for 6 years and was on the pill before that.

4 Comments
2024/12/05
01:31 UTC

2

I live streamed my sleep and applied 21 sleep hacks over 3 months. The funny thing is...

1 Comment
2024/12/05
00:47 UTC

1

Does anyone here have recent insights on Durk Pearson, who just passed away in October at the age of 81?

Durk Pearson and his wife Sandy Shaw were two ground breaking innovators in biohacking and life extension with their 1982 book “Life Extension - a Practical Approach”

Sandy Shaw, it seems, passed away around three years ago.

Can anyone here provide any insights/links to provide info on their later lives and whatever issues might have caused them to leave us much too soon?

Thanks!

2 Comments
2024/12/05
00:21 UTC

2

Do you think I can get enough vitamin D sitting by…..

Do you think I can get enough vitamin D sitting by a big window like that in the office everyday.

You know, winter is coming. Just wondering if I should get vitamin D ready.

Located in BC, Canada

Please share your ideas. :)

https://preview.redd.it/ju8gp9ei9x4e1.jpg?width=1512&format=pjpg&auto=webp&s=bba0236e20af71bd2dd0475883d00cd4fea303eb

35 Comments
2024/12/05
00:11 UTC

7

⚠️ATTENTION⚠️

Everyone needs to search “EWG tap water” and type in your zip code.

It tells you the quality of your local water supply. The results for me were shocking.

Everyone should invest in a high quality filtration system. Share your results below.

25 Comments
2024/12/05
00:09 UTC

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