I have been tracking this phenomenon and its second order effects personally for a year now. Metformin enables rapid passage of food through the gut (which has the upside of excreting your excess sugars/carbohydrates through loose-esque stools without absorbing them into the bloodstream) but it also means that your gut does not get enough time with the ingested material to absorb nutrients from it optimally. If you're eating a meal right after taking metformin that consists of, say, bread, eggs and some high-vitamin fruits, I'd have them in that order but spaced out, so that the more nutritious food comes in as late as possible, after you have ingested and started digestion of your carb-heavy food, and enable the good guys to suffer least from the metformin effect.

Yogurt Enema is a thing brought to you by the maker of kellogs cereal. The idea is that you can recolonize your colon with healthy gut flora- but what is healthy for me might not be healthy for you. More research is needed.

NOTE: Dont use cornflakes in the enema.

For educational purposes. . . If I took Bulletproof and Gabba then added a Trazodone prescription. Would it be dangerous or just a sure way to fall asleep?

Anyone have experience with this extract? Recently learned about it from guest host Dr. Stacy Sims on the Huberman Lab. She adds it to her coffee for an added energy and focus boost. Any experiences out there?

While searching Peptides I came across livvnatural. Their website seems very off. I hope this does not correlate to their products. None of their links to their socials work. Maybe "fake reviews", and their support informed me that to mix the BAC water they ship a pre -filled syringe, but in the video (that is hard to find) it shows them using a vial, and not using the syringe.

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Is anyone in the biohackers sphere just raw dogging life and diet, no supplements? Or trying it out as an experiment?

What made you do it? How's it going?

I'm considering experimenting where I drop to just a multivitamin, or maybe drop everything all together. Been doing the research and most things seem feasible to get - things like weekly liver, oysters, salmon, red meat, mixed nuts, help cover a lot of nutritional bases. Vitamin D obviously can be from the sun, but the east coast isn't giving much these days so with daytime work schedule that can be a bit of a tricky one. Oh and magnesium actually seems tricky to get a good quantity like 400mg (food tips appreciated).

Why in my case? I'm doing well tbh taking ~6-10 different things that seem good, but it's just kind of annoying and onerous sometimes, and philosophically I just don't like the idea of being so high maintenance. Hard to explain, maybe some of you get it.

Anyways curious to hear from y'all.

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https://pubmed.ncbi.nlm.nih.gov/33594677/

Started taking it mostly for weight control/loss, but just a few days in. Taking the BodyBio brand found on Amazon. I feel slightly achy, but I also think it's because I'm not hungry and eating/drinking less.

Any experiences or thoughts are appreciated

Looking at my magnesium intake from cronometer, I'm getting between 700-800mg of magnesium per day through my diet alone.

I assume everyone else here is eating real, unprocessed, whole foods (since that's easily the #1 "biohack" by a substantial amount) and likely consuming a similar amount, so why are so many people on here supplementing it?

Is the RDI amount far below what people on here believe the value should be? Is the magnesium obtained via food not as easily absorbed as when consumed in supplement form?

I feel fairly confident in saying my wife (45F) is going through early menopause. Any supplements that can help with the hormones and possible acne? TIA

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I've struggled with low test and low libido, things seem to be getting better at the moment. I was wondering if adding these in might help since I am on the lower end of B12. Please let me know what you think. Thank you

I’ve got all the wearables, but the data is spread.

I’ve tried to keep track of my symptoms (gut, mental health etc.) but are manually correlating my symptoms, treatments, exercise, stool and food intake in Google Sheets.

It’s almost like the data collection is too sporadic – and it’s hard to keep up. The cost/benefit isn’t great.

How do you track your health and correlate it with your treatment on an on going basis?

I am currently taking Nac, magnesium, a methylated b vitamin and some vitamin D and k2.

I had read NAC will chelate copper but at this point I think it may be better to get a multi vitamin than continuing to get supplements one at a time. Any good recommendations for a multi vitamin for men that contains copper?

Hello everyone, I (24m) want to know what things you do to help with depression. I feel like physically I'm doing great. Very active, yet it feels like my brain is behind. Low motivation, depressed tendencies, emptiness. Classic depression symptoms. I'm in therapy and we're doing lots of trauma work (Diagnosed with c-ptsd) but it's been getting hard lately and just want to hear what bio hacks you do to keep you doing better.

What helps with low dopamine?

What helps with really low moods?

Things I'm currently doing: Sunlight in morning, 5-10m meditation everyday, exercise for 1-2 hours, regularly hang with friends / family, supplements (High epa fish oil, vitamin d, magnesium glycinate, valerian root, coq10).

Things I've tried: EFT tapping, acupuncture, supplements (Rhodiola, NAC, Taurine, Saffron, Turmeric, Ashwaghanda, L-theanine), cold showers, yoga, magic mushrooms, journaling

Things I've considered: Medication, Biofeedback, elimination diet, specialist blood work

Some other notes: Gotten blood tests done and everything looked perfect. Got a sleep study and they diagnosed me with insomnia.

I want to know what has worked best for you guys, what your experiences are with some of these and if there are any other ideas / suggestions. I've tried a lot of things, but feel like I'm not making progress. Thanks :)

I donate plasma, but desperately trying to stick to the keto diet. I keep failing at it, but I keep getting back on the wagon. They say after you donate plasma, you need to eat a snack. A couple weeks ago I did my first full donation and I DEFINITELY need snacks afterward, even though I ate dinner beforehand. I had 2 beef sticks, a York peppermint patty, and a small bag of potato chips.

The reason I need to stick to Keto is for digestive purposes.

This time I don't even want to eat chocolate after, it is starting to make me constipated.

Tonight I will bring a small bowl of brown rice, but I really prefer to not eat ANYTHING starchy or high in carbs at all.

I have heard many times that eating in general raises your blood sugar. Any advice?

I have severe insomnia, especially waking up in the middle of the night. I also have symptoms of MCAS (acne, dry throat, brain fog) and I have allergy symptoms.

Also, recently I was only able to sleep 2-3 hours no matter how many bzds I used, which was really bothering me. Even with the addition of trazodone, I was lucky if I could sleep 3 hours.

So I tried antihistamine + trazodone and was surprised to be able to sleep 7-8 hours.

I especially tried Famotidine as an antihistamine, at 2-3 times the normal amount. I've only used the normal amount up until now (which didn't work), so is it important to increase the amount?

I have been refractory, especially waking up in the middle of the night. I also have symptoms of MCAS (acne, dry throat, brain fog) and I have allergy symptoms.

Also, recently I was only able to sleep 2-3 hours no matter how many bzds I used, which was really bothering me. Even with the addition of trazodone, I was lucky if I could sleep 3 hours.

So I tried antihistamines + trazodone and was surprised to find I could sleep 7-8 hours.

I especially tried Famotidine as an antihistamine, at 2-3 times the normal dose. I had only used the normal dose (which didn't work), but is it important to increase the dose?

I've tried Mirtazapine before, but even with the bzd I could only sleep 2-3 hours. What's even more strange is that I seem to get more benefit from half the dose, 3.25mg, than from 7.5mg.

If antihistamines work for sleep, are there any other drugs worth trying? Also, are bzds actually counterproductive to deep sleep? Because it was only when I started using Clona that I started sleeping 2-3 hours. At first, I thought that using Clona had caused cross-resistance with other bzds, rendering the bzds I had been using ineffective, but in reality, that was not the case. Rather, was using bzds making my sleep shallower and disrupting it?

I've talked a lot, but to summarize, what I want to ask here is

①Is there a deep relationship between sleep and allergies?

②Considering my background, what other important allergy or histamine-related medications are there? (By the way, even a small amount of Quetiapine had the side effect of making me thirsty and comatose, and unable to get out of bed, so it was completely useless. Perhaps because I have MCAS, I have a tendency to be hypersensitive to drugs.)

③Is it possible that using bzd medications themselves makes my sleep shallower and actually disrupts my sleep?

Furthermore, this is a new question, but

④Unrelated to what we've discussed so far, what medications or supplements do I need to deepen my sleep? Just to be clear, I don't have any trouble falling asleep. The problem is waking up in the middle of the night. This is especially worse during seasonal changes, when I often wake up with my body flushed and my heart pounding.

This post is getting long, so even a partial answer would be appreciated, as I am ignorant. Also, if there is anything else I should know about sleep or health (given my background) that is not related to this question, please let me know. I am using Google Translate to write this post, so I apologize if there are any parts that are difficult to understand.

Hi all, I purchased the 5 strands hair test for mineral deficiencies and got this data back. My hair is down to my shoulders so it's probably 2 years worth of data. I've been increasing strenuous exercise during this time, including running half marathons. What surprised me was the big calcium deficiency. I don't have a great diet, but I do eat a ton of dairy and my annual blood tests have always shown normal blood calcium levels. I wasn't low in Vitamin D. So, why is approximately two years of my hair data suggesting I'm seriously calcium deficient? I worry because my mom has early onset osteoporosis and I've been doing my best not to follow in her footsteps.

Also, I deal with occasional heart palpitations. I wore a holter monitor and the docs weren't worried because they seemed to be just a symptom of stress and caffeine and low iron, but now I'm wondering if that could be connected to any of these other mineral deficiencies. Any thoughts here??? Help!!!

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I think it makes sense that if you're healthy you tend to walk faster.
However, do you think that walking speed should be considered as a vital sign?

Has anyone tried neurofeedback? I tried this about 25 years ago and have not succeeded in manipulating any of the brainwaves. It is more complex than it looks.

Hi guys,

Just invested in my first red light therapy panel. I bought a flowlight 1500. It has

• 630nm, 660nm, 810nm, 830nm, 850nm, 940nm, 1060nm.

-300 led -190mW/cm2 at 15cm

• 1-10000Hz

So I am wondering. How often do you recommend using it? And for how long do you recommend using it?

Also, should one do the front of the body and then the back? 😂 or is it enough to just sit/stand in front of it.

Shares experience is appreciated.

I’ve been taking NAC for the past couple of days with great results. It’s been life changing. I’m seeing some people online say that it can deplete certain nutrients and that it should be taken with glycine. Does anyone have more information on this? I’m currently taking vitamin D, fish oil and zinc along side the NAC. I don’t want to run into any problems in the long run.

Hi!

Some of you may have seen my post yesterday with my long list of symptoms.

Well, having analysed the last few weeks I notice that I feel best when I haven’t recently eaten. When I’m hungry. Heart is calm, I have zero symptoms, I feel good. Apart from when it gets to the point of less energy and feeling super hungry…

So, clearly, my body is reacting to things (really thinking histamine/sibo/mcas/candida?!). When I eat certain things (that I haven’t yet managed to pinpoint the exact thing as my plates have many many different ingredients in!) So I need to do a diet where I start from scratch…?

So my question is. What foods can I eat where I am still getting the correct nutrients for a woman in her early 30’s? My folate and potassium are already low. I don’t react to meat. (Phew) Can’t do mayo. Haven’t tested out just ‘eggs’. My body hates beans.

When I go food shopping what do I buy? Because I’m finding myself not wanting to eat in fear of the symptoms that may occur as a result (fast heart, high BP, feel too hot, feel nauseous, facial flushing, dizziness, feeling faint, etc) When this happens my heart js like 120-130 just standing… but the rest of the time without these episodes, my heart goes just from 75 to 85 standing, NOT postural orthostatic tachycardia syndrome. But I would tick that box if I am reacting to a food…. Wild.

Anyway 😭😂🫣 help with foods so I don’t become deficient or worsen my low folate/potassium?

Thank you in advance 🙏🏻