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Reasons to hope to see the age of 100 and beyond: Biomedical rejuvenation through damage repair, manipulation of metabolism, beyond the mere results of exercise, caloric restriction, and fasting. Stem cell therapies, anti-cancer viruses, gene therapy, senolytics, and whatever is coming next...

/r/longevity is the place to find all information about new longevity, healthspan, happyspan, and rejuvenation research related news.

Welcome to r/Longevity

Feel free to discuss longevity-related topics, share the latest aging research, media, news, and articles! Just be sure to not post clickbait headlines, avoid hyperbolic headlines, and try to link to original sources.

General Subreddit Rules and FAQ.

This subreddit is not about solving problems that can be solved by diet (/r/ScientificNutrition), supplementation (/r/supplements), sleep, exercise (/r/fitness), or fasting (/r/fasting, /r/FMD). A good lifestyle helps increase the percentage of the healthy part of a life span, as well as reduces the risk of early death or chronic sickness or disability but does not help in defeating the inevitable age-related disease.

There is nothing on the market as of right now (2024) that you can purchase or sign up for and get some of the benefits that are the aim of this subreddit (addressing multi-factors of age related damage and disease). The goals that are part of this subreddit's theme are being worked on in the form of very early research, and the expected time frame of such advances hitting the market are years away, but we are here to follow the progress.

Subscribe if that interests you :)

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Message the moderators if you work in the industry/research and want to be recognized.

Links to external Longevity-related sites



Longevity Wiki

Outline of Life Extension on Wikipedia

Index of life extension related Wikipedia articles

Aging in Motion
Aging Matters
Alliance for Aging Research
Alliance for Regenerative Medicine
American Academy of Anti-Aging Medicine
American Aging Association
American Federation for Aging Research
American Society on Aging
Blue Zones - /r/BlueZones
Brain Preservation Foundation
British Society for Research on Aging
Calico Labs
Caloric Restriction Society
Church of Perpetual Life
Coalition for Radical Life Extension
Dog Aging Project
ELPI Foundation for Indefinite Lifespan
Fight Aging! Blog
Found My Fitness
Friends of NIA
Gerontology Wiki
Global Healthspan Policy Institute
Health Extension
Healthspan Campaign
Humanity+ magazine
Humanity+ wiki
International Cell Senescence Association
International Longevity Alliance
International Longevity Centre Global Alliance
International Society on Aging and Disease
Juvena Therapeutics
Juvify Health
Leucadia Therapeutics
Life Extension Advocacy Foundation
Life Extension Foundation
Lifeboat Foundation
Loyal for Dogs
Longevity History
Longevity Vision Fund
MDI Biological Laboratory
Methuselah Foundation
New Organ Alliance
Oisin Biotechnologies
Organ Preservation Alliance
Palo Alto Longevity Prize
Rubedo Life Sciences
Stealth BioTherapeutics
The War On Aging
Unity Biotechnologies
Water Bear Lair

Informational Sites:

Programmed Aging Info
Senescence Info
Experimental Gerontology Journal
Mechanisms of Ageing and Development Journal

Schools and Academic Institutions:

Where to do a PhD on aging - a list of labs


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Biotech company aims to extend dogs' lives. Here's how it'd work.

1 Comment
14:52 UTC


on the parallels between aging/longevity as a field & the Artificial Intelligence field

Artificial Intelligence as a field has much in common with the aging/longevity field. I hadn't realized how many parallels until thinking about it this week. (These are my former & current fields, respectively.)

A list of similarities:

  1. A long history in fiction.
  2. Huge complexity necessitating many decades for serious progress.
  3. Fraud (eg in AI it goes all the way back to the 18th century "Mechanical Turk", a man in a box pretending to be a machine that could play chess).
  4. Immensely great importance to the world.
  5. A central underlying concept that is hard to define & about which there is much debate amongst in-field experts but every lay person easily knows it when they see it: intelligence & aging, respectively.
  6. Clear motivating existence proofs: human intelligence for AI & for aging (a) negligibly senescent species, (b) germ-line rejuvenation, & arguably (c) indefinitely maintained (classic) cars. But despite the existence proof, still uncertainty whether those can ever be fully replicated in the desired system: human intelligence -> machines; neglible senescence or rejuvenation -> (entire) humans. And outright debate within the fields about achievability.
  7. Despite skepticism in some, optimism in many based on appeal to underlying reality. For AI, a famous quote sums it up: “The human brain is just a computer that happens to be made out of meat". For aging, the body is just a machine that happens to be made out of molecules.
  8. Both fields are fundamentally combinations of science & engineering: both require study of the existence proofs but development of new techniques for building/manipulating to achieve the desired result.

This sort of leads to 9... 9. Both are highly multidisciplinary: AI: cognitive psychology, neuroscience, computer science, robotics (& mech eng), vision/graphics, data science & statistics, etc. Aging: biology, chemistry, genetics, immunology, neuroscience (common to both), nanotechnology, etc. 10. And despite fraud & complexity, nonetheless both fields have a proper scientific grounding & actual clear progress.

One could prob go on. Eg both will create huge society changes & be called booms & revolutions like the internet & smartphones (but sort of corollary of 4).

There are other notable connections between the fields even if they aren't similarities: Interestingly, many people who used to work in AI now work in aging (like me), or want to make that move. Maybe some of these parallels are what draws folks in this direction?

My vague sense is that aging as a field is ~2-4 decades behind AI (so maybe where AI was in 80s or 90s).

Some think AI will play a key role in aging progress. I agree some but not that we can just let AI do it all for us soon.

03:26 UTC


Taurine Extends Lifespan (In Mice): What's My Data? (6-Test Analysis)

11:15 UTC


Dr. Kiprov talks about benefits of therapeutic plasma exchange

08:04 UTC


19.5y Younger Biological Age: Supplements, Diet (Test #2 in 2024)

1 Comment
19:28 UTC


Dr. Bruce Ames, now 95, proposed his Triage Theory of Aging which suggests scarcity drives micronutrients like magnesium, crucial for DNA repair, to short-term survival enzymes, risking long-term health. This episode explores magnesium's aging role, cancer, DNA damage, cognitive effects, and more.

17:49 UTC

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