/r/pregabalin

Photograph via snooOG

A subreddit to discuss Pregabalin, otherwise known under the brand name Lyrica. Harm Reduction practices followed.

A subreddit to discuss pregabalin, otherwise known under the brand name Lyrica from Pfizer. This prescription drug is used for treatment of various types of pain, seizures, and general anxiety disorder. It is a structural analogue of GABA but does not actually bind to the GABA receptors as benzos do. While it interacts with different parts of the brain to benzos the effects are similar or even enhanced depending on dosage and tolerance.


Related subreddits:

/r/pregabalin

10,326 Subscribers

1

Has anyone been able to lose weight while on pregabalin ?

Exactly this I have gained so much

1 Comment
2024/11/03
01:31 UTC

1

Side effects

I started pregabalin atleast a month ago . They upped my dose so I'm at 150. I'm also on venlafaxine and quitiepene. Since then I had experienced tremors . Today being the worst I had to go to the hospital. Prior to this my vagina was fine . But now it's inflamed and on fire. I have done nothing different or changed anything different so why am I having an allergic reaction down there ? It was so bad it was blistering. Swabbed for herpes not that. Has anyone else had this problem

0 Comments
2024/11/02
00:49 UTC

3

Pregabalin + Wellbutrin (Bupropion)

Hey guys and gals, I was wanting to know if anyone is or has had experience with taking these two.

I went in to see my doctor April this year as I was dealing with GAD. (health anxiety) and I was first put on Escitalopram (Lexapro) and after about 4 to 4.5 months of it I switched out due to some libido issues on Escitalopram..

So August 2024 I tell my doc about that and he said let's try Wellbutrin (150mg XL) in the morning (I take it early in the morning 7am as instructed) and then at night I take Pregabalin at night. (Pregabalin is dosed at 50mg).

It's been now about 3 months if not 3.5 months and yes I do feel great but I guess my question is does anyone else run this combo? I would like to eventually get off this stuff but does anyone have more insight on what exactly makes Welbutrin effective in the morning and then pregabalin at night? What do they do for my anxiety that i need to take both? Do they just work better at those times of day? I feel great, and I again, want to eventually get off this stuff slowly with my doctors advice but would love to hear your feedback good or bad.

Thank you for reading, and I hope you all are having success overcoming your anxiety and having the best success with your mental health.

9 Comments
2024/11/02
06:40 UTC

2

Pregabalin with buprenorphine

I am starting lyrica with buprenorphine for my spinal injury. I have felt like buprenorphine has not taken that much pain away for a while. I am just wondering what to expect from lyrica. I have not heard of it before. Would appreciate any talk of experience available

2 Comments
2024/11/02
01:00 UTC

1

Just started pregabalin …!

I just started pregabalin - lyrica 75mg first 30mins i felt very anxious and something bad about to happen to me , then i started feeling relaxed and the negative thoughts and anxiety flew away like you snap your fingers , then after couple of hours started feeling that I’m very high and every time i smoke a normal cigarette i feel higher after that started feeling like im comfortable and all my body hurts me and very weak i can barely walk i felt like im in a bubble and the world isn’t real , that was experience with lyrica for the first day should i continue taking and that symptoms will go away or what should i do

1 Comment
2024/11/01
19:08 UTC

1

Pregabalin for Benzo Taper?

Hey guys 🌸 I am tapering Valium right now. I started with 13mg and I am down to 2.5mg. The withdrawal is extremely hard. I hit a wall last week and my biggest issue is EXTREME pain and muscle tension. I break down everyday because of the pain. No normal pain killers work and also a muscle relaxant didn’t work.

My doctor prescribed me Pregabalin 2x75mg a day. Can you tell me if you had success with Pregabalin for benzo taper? How much did you take?

I am scared of Pregabalin dependence but right now I would do anything to reduce the pain. It is unbearable.

I would love to hear (positive) experiences. Or other tips to reduce the tension and pain from tapering Valium.

Thank you 💜

0 Comments
2024/10/31
14:03 UTC

6

Food

For half my life, I have been unable to tolerate carbs. I get extremely low-energy and pretty depressed. I have been on a keto diet for the past 9 years. But when I take pregabalin. I can eat whatever without any side effects, I feel pretty good. What's up with that?

5 Comments
2024/10/31
18:56 UTC

1

Advice

Took lyrica 75mg at 12am this morning don’t know if I took one before. I normally don’t follow a specific scheduled time to take, I just take randomly. Woke up today with headache, jittery feeling in head .. I also took Prozac which I don’t think had an effect but will this feeling pass?

14 Comments
2024/10/31
16:22 UTC

1

How to Taper- 75mg x2 daily

Any advice on an appropriate taper? I've been on 75mg twice daily for two months in response to an anxiety episode. I only have 75mg capsules so may see my doctor about getting 25mg or other. I don't think it's the drug for me as I noticed hair thinning/changes in texture.

1 Comment
2024/10/31
01:05 UTC

5

Unusual, jittery reaction. Does this go away?

Just started pregabalin 75mg 2x a day for fibromyalgia. Only took it 3 times.

It did not make me feel sleepy or relaxed at all. I felt a little less pain but I mostly felt like everything was moving very fast and I was jittery, mildly dizzy, and had almost no recall.

Called my rheumatologist and he dropped the dose down to 50mg 2x a day but I’m afraid to take it. I’m currently working full time and going to school and have some pretty challenging classes. I can’t afford to not have my brain on board and the fact that I reacted so differently has me a little spooked. Is this just a first couple of weeks type thing or is this just not the medication for me?

22 Comments
2024/10/29
22:52 UTC

1

Hallucinations after taking 300mg

It was my first time with pregabalin, though I've been prescribed gabapentin 400mg for sleep and RLS for over a year now.

I took 300mg pregabalin and 2 hours later I was super uncoordinated. About an hour after that the visual hallucinations started and lasted for over 8 hours. It was terrible!

So I guess I should have started with 75mg? I'm taking it for the same reasons as gabapentin, which stopped working and which I stopped taking.

5 Comments
2024/10/29
15:08 UTC

1

Anyone with ectopic beats taking pregabalin? Artial flutter? Does it make things worse? What’s your experience?

0 Comments
2024/10/29
16:44 UTC

5

Pregabalin for RLS

Hi everyone, my doctor prescribed me with pregabalin yesterday predominantly for RLS, i have insomnia but obviously the RLS makes it way harder to sleep than it already is. I also have something else going on that i think and he seemed to think is possibly brain related but it’s stumped him and everyone else i have spoken to about it, so we are gonna see if it helps this thing as well.

I am quite scared to start taking it for some reason, so i was wondering how it effects people’s sleep and if there are any common side effects i can tell myself are from the medication so i don’t worry about it loads.

I have been on quetiapine, mirtazapine, sertraline, prozac and venlafaxine before and they have all either not helped or have given me really bad side effects and im scared this one will too.

8 Comments
2024/10/29
11:40 UTC

4

numbness emotionally

is anyone else feeling kind of numb emotionally or lacking emotional variety on lyrica? maybe it’s my seasonal depression starting again or i’m just not as emotional as i was when i was anxious constantly before pregabalin but idk maybe it’s a side effect

17 Comments
2024/10/28
10:03 UTC

3

Pregabalin/insomia

Trying to get off of lyrica at the lowest dose of 25MG, my only problem is the insomia when discontinuing the medication which unfortunately keeps me on it. anyone else know how to deal with the drug induced insomia? How did you get off this drug..

27 Comments
2024/10/28
08:19 UTC

2

Dose?

What dose is typical for anxiety?

21 Comments
2024/10/27
12:28 UTC

1

Lyrica withdrawal insomnia. HELP

Hello,

I have been using 300 mg mostly 600 and very few times 900 mg pregabalin. I had no chance to taper down, and I went cold turkey. I have some anxiety but the most awful one is insomnia. I can’t sleep. I sometimes sleep for 1-2 hours and all of a sudden bounce back up. Could you please help me ? When will this subside?

1 Comment
2024/10/26
15:09 UTC

1

for schizophrenia?

is it used?

1 Comment
2024/10/26
22:28 UTC

1

Annoyed with NHS

I have a repeat prescription for pregabalin which my psychiatrist just increased. I submitted a prescription request and said in the notes that I will be requesting another prescription in the same month as the dose had increased. The official dose was coming through from the psych, I just needed to make sure I could get the repeat. I told my psych I had 4 days left and she put this in the email to the gp.

Went onto the nhs app before going to the pharmacy and glanced at it and saw it had been approved. Got to the pharmacy and they didn't have anything, last thing was 7th oct. But the dose had changed to the new dose on 7th even though the new dose happened this week.

Can't get an emergency script because it's controlled. Called 111 and got out of hours gp call back, they can't prescribe because it's controlled. Spoke to my friend who's a dr who said she hasn't issued a repeat in a&e before, spoke to another friend to ask if in his experience a&e would do it and he said they could but wouldn't like it, plus wait times would be long.

How is the gp the only option here? I get that they issued the prescription in the first place, and that it's controlled. But it's on my repeat prescription which shows that I’m allowed to have it. Sometimes I do forget to order meds on time which is my fault. But I definitely made sure I ordered this in advance and with the notes and the notes from the psych to gp.

Has anyone else experienced this and have any other options I haven't considered? I'm also taking venlafaxine. Thanks so much in advance

4 Comments
2024/10/26
22:38 UTC

2

Meralgia paraesthetica

As in my title, I’m taking pregabalin for numbness in my thigh. It’s been a week and a half but I’ve found out that I have been struggling to sleep with & without it. It takes hours for it to finally kick in and that’s when I feel the most of it. Then I feel that I’m able to finally sleep. That being said, I heard that this pill is highly addictive and I’m scared that I’ll be dependent on it to fall asleep. Should I continue until taking it until I notice a change in my mindset or should I stop beforehand?

5 Comments
2024/10/27
01:20 UTC

2

Fibromyalgia and CFS/ME

I have severe Fibromyalgia and CFS/ME (Myalgic Encephalomyelitis) and am mostly house or bed bound. One of my worst symptoms is general body aches, a deep dull feeling like my entire torso is in a vice and is being pressed, while also feeling very weak. Initially doctors thought anti depressants could help but they were very wrong. Initially i was on Escitalopram for 4 months and it did nothing other than kill all my emotions. I could no longer cry or laugh it was very strange. so i quit which was very difficult. i was then put on venlafaxine which made me suicidal after 6 months and I also had to quit it too. finally i was prescribed amitriptyline 25mg which helped with sleep but not pain. but my body seems to have built tolerance for amitriptyline and i no longer feel any side effects or benefits.

I’m still on amitriptyline but also have been recently prescribed Pregabalin 50mg to take as needed. This has helped with my nerve pain tremendously specially if i take it with Advil together. But I have discovered that i quickly built tolerance after 10 days, and my body no longer feels any benefit from a 50mg capsule, but it does still somewhat help with pain unlike amitriptyline. I’m wondering if Pregabalin is a safe long term drug and if I can ask my doctor to increase its dosage? I have heard of some horror stories about drugs like gabapentin, TCAs, SNRIs and SSRIs. I’m unfamiliar with Pregabalin and not sure if it can be a long term solution for my severe fibromyalgia pain. Thanks.

11 Comments
2024/10/26
16:32 UTC

5

Weight gain?

I had been on sertraline for 10 years, varying dosages. I have also been on propranolol 80mg and also tried citalopram for 7 months. My gp wants me to taper off citalopram and try pregablin as a "last resort". I have also suffered from anorexia in the past, and scared of weight gain. Surely weight gain can only be caused off too many calories? As water weight is not actual weight? No?

10 Comments
2024/10/25
19:50 UTC

1

Pregabalin vs trintellix?

Thinking about changing from pregab to vortioxetine for my anxiety due to breathing problems with lyrica. Anyone that has had experience with both and can give some feedback?

0 Comments
2024/10/25
19:18 UTC

4

Dosage for your anxiety?

I am currently on 50mgs x2 daily 4 weeks today but I feel its not enough, I am still battling physical anxiety really bad.

Wondering what doses worked best for both physical and mental anxiety?

32 Comments
2024/10/25
16:07 UTC

2

Will side effects diminish?

Hey, I take pregabalin 150 mg twice a day. My doctor recommended taking 150 mg in the morning and 300 mg in the evening. I'm taking it for social anxiety and generalized anxiety, and it's my first week on it. ChatGPT mentioned I should feel some improvement.

To be honest, it’s hard to tell whether I feel any improvement because of the side effects. I still experience restlessness when sitting alone in my room (like an urge to scratch myself or bounce my leg), brain fog (confusion), a weird lightness in my hands and legs (like I might drop what I’m holding), and slight dizziness.

It’s unpleasant, and I’m not sure if I should mention it to my doctor or wait a bit longer.

I take 60 mg duloxetine for depression also.

10 Comments
2024/10/25
12:30 UTC

1

Lyrica

I took Lyrica about 6 years continuously

I wanted to ask I did stopped it three years ago But still feeling bad, still feels I need it Suffering insomnia, Feeling scared, confused and shy

I don't feel the taste of life

I can’t understand why, or should I live with it It’s not so easy for me now to see a doctor, but I just wanted some advices Thanks

0 Comments
2024/10/24
20:05 UTC

3

Pregabalin

I did took Lyrica for 6 years continuously And did stoped it 3 years ago I feeling more anxious, suffering insomnia,

feeling scared, confused and shy And don’t feel the taste of life, wanted to know if somebody else faced the same What can we do, should we go back to Lyrica? Thanks

4 Comments
2024/10/24
20:18 UTC

2

Started pregabalin 4 weeks ago.

Hello all,

I’ve started pregabalin 4 weeks ago, slowly titrating the dose.

My anxiety had gotten very bad and I’m Starting to experience panic attacks. Is this normal? Did anyone else experience this? Not sure if I should stay on the medication or not. Feeling like this is never going to get better while on it.

19 Comments
2024/10/25
00:37 UTC

3

Venlafaxine and pregabalin, safe?

I currently on venlafaxine 150mg, its safe add pregabalin together?

8 Comments
2024/10/24
18:15 UTC

1

pregablin + alcohol

i mix the two pretty regularly on 50mg twice a day, not drinking “heavy” but enough to be drunk, and i feel great other than feeling pretty short of breath but i can’t tell if this is just a symptom of my own anxiety or something other people experience when they mix the two.

1 Comment
2024/10/21
07:11 UTC

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