/r/neuro

Photograph via snooOG

/r/neuro, involving neuroscience: Discussion and news pertaining to neurobiology, cognitive studies, clinical neuroscience, the laboratory, and anything else related.

We're a bit laid back here, you're free to post anything about neuroscience as long as it doesn't break the rules. For more academic discussions of journal articles, /r/neuroscience is a great place.

/r/neuro, involving neuroscience: Discussion and news pertaining to neurobiology, cognitive studies, clinical neuroscience, the laboratory, and anything else related.

We're a bit laid back here, you're free to post anything about neuroscience as long as it doesn't break the rules. For more academic discussions of journal articles, /r/neuroscience is a great place.


Community Rules:

1. No personal or health-related discussion

This especially includes medical advice, clarification, diagnosis, and discussion of symptoms, drugs/supplements, medical procedures, etc. but any post containing personal or health discussion may be removed at moderator discretion.

2. Claims must be cited appropriately.

Posts that assert a positive claim about the brain must include a link to a peer-reviewed or pre-print article to support that claim. This rule doesn't apply to questions, speculative discussion that is properly caveated, or very basic neuroscience facts.

If you reference any study or if you post a link to a news article coverage of a paper, you must submit a comment with a direct link to the paper if the article you post doesn't have one.

3. Content must be related to Neuroscience.

If your post is not related to the brain, this is not the community for your post.

4. Site-wide content rules also apply.

No bullying, brigading, doxxing, illegal content, etc. Be nice; we're all humans here.


Some other subreddits you might be interested in:

See also the full list of Psych/Cog/Neuro subreddits.

/r/neuro

112,796 Subscribers

5

Masters in neuroscience realistic? (Series of unfortunate events where everything ever went wrong)

I want to do a masters in neuroscience with a Philosophy with Psychology degree from the uni of Warwick and I don't know how realistic it is, because last year everything ever went wrong forever.

Essentially the year weightings here are 0%, 50%, 50%. In first year (worth 0%) I got a first, things were good. Second year I got very ill and had to take a term out so couldn't complete my exams. Due to (largely) an admin error (plus some other things) I was forced to take a whole year out. They told me this apologetically over a call. Things really sucked because I had to work and survive and life became a bit grim.

I was taking 2 third-year out-of-department modules (machine learning and neuroscience) as a second year and this didn't help. To put it simply my grades for second year - especially those modules - absolutely tanked. On the upside I published a paper (the topic is irrelevant to neuroscience though) and got invited to the royal society and got some research experience over the past 2 years, working with EEGs and BCIs and computational models...

...and then my research partner terminated our project with no warning and no credit.

Now in third year. Making up for my horrible second year grade is actually basically impossible (well, highly implausible). I'm expecting to get a high 2:1 at most. Also this year I can't take out of department modules which means everything is philosophy and psychology and not neuroscience.

Back before everything went horribly wrong I emailed oxford neuro about whether phil+psych is even considered as a relevant degree and they actually urged me to apply. Now after the grade-tanking research-ending experience of last year I have no idea whether this is realistic at all; not just for Oxford but for any top uni. Or for any university at all. Oh, also I have no idea exactly precisely what I want to do in neuro, just the general vibe/area.

And the deadline is 3rd December for the application. (Having an anxiety attack as we speak actually). Any insight or feedback or anything ever appreciated x

6 Comments
2024/10/14
21:08 UTC

0

Psychiatry serves as a temporary placeholder for the concept of 'God of the gaps' in neuroscience.

Filling the gaps isn't a question of if, but when.

8 Comments
2024/10/13
20:04 UTC

465

Why don't psychiatrists run rudimentary neurological tests (blood work, MRI, etc.) before prescribing antidepressants?

Considering that the cost of these tests are only a fraction of the cost of antidepressants and psych consultations, I think these should be mandated before starting antidepressants to avoid beating around the bush and misdiagnoses.

343 Comments
2024/10/12
13:33 UTC

1

Seeking Volunteers for South Asian Women in Neuroscience(SAWiN) Initiative🌍🧠

I’m launching SAWiN (South Asian Women in Neuroscience), a collective dedicated to empowering women from South Asian countries—including India, Pakistan, Bangladesh, Sri Lanka, Nepal, Bhutan, and Maldives—who are either pursuing or interested in neuroscience.

We’re looking for passionate volunteers to help with community building, event planning, content creation, and mentorship program development. If you or someone you know from these regions would like to contribute to this initiative, we’d love to have you join us!

Please share this with women from these areas who might be interested, or reach out to learn more about getting involved!

0 Comments
2024/10/11
15:45 UTC

61

perfusing mice makes me feel like a serial killer

Does this feeling go away? I can perfuse just fine on a skill level, but the entire process is hard for me to stomach. Stereotaxic surgery I have no problem with, but perfusions are so difficult mentally for me.

Does anyone have any advice?

38 Comments
2024/10/11
13:31 UTC

15

Why is it difficult to develop an effective tratment for treatment-resistant depression?

Is it difficult because we don't understand the brain sufficiently and what's going wrong or is it because we can't control neural activity precisely enough?

29 Comments
2024/10/11
08:19 UTC

3

Is QEEG legit?

There are companies offering QEEGs and claiming that they can know which waves are generated where, e.g. the amygdala, etc.

They claim qEEG can show patterns that are indicative of things like ADHD, anxiety, etc.

Based on that, many companies then offer tailored TMS or neurofeedback.

Is this a massive scam or is there some truth in it?

2 Comments
2024/10/09
11:52 UTC

3

Post-Traumatic Stress Disorder by Charles B. Nemeroff

Hi everyone,

I'm wondering if anyone can give me a review of the above text, I'm thinking of grabbing it when I can, as I'm looking at doing my thesis on PTSD. Is it worth it? Are there better texts?

Thanks in advance!

0 Comments
2024/10/09
04:51 UTC

75

Let's learn neuroscience together

Hi all,

About myself: I am a neuro grad student. I love to learn about neuroscience outside my specialized area, but I have little time to do the research properly since I'm working in the lab and writing for my own work.

My idea: Let's build something together and help each other learn. I've started a discord server and I plan to populate it with my knowledge base in a way that is hopefully palatable for other readers. I would like it to be a place where people can lay out complex information in an easily digestible manner for those who are not as well studied on the topic.

If this catches anyone's attention feel free to DM.

34 Comments
2024/10/08
23:58 UTC

0

Opioid Kappa KOR autoreceptors/inhibitory receptors/agonists

Hi,

  1. Are there any autoreceptors/inhibitory receptors for KOR as they are in dopamine receptors like some d2/d3 receptors? Like K2R or K2?

  2. Do You know any natural selective KOR agonists?

I want to trigger a little KOR agonist for night that the next day my body will produce less dynorphins so dopamine would not be inhibited. I thought of taking menthol but I don't want to supress my testosterone and dht production. Does anyone know about a trick that would do that? I don't want to play on antagonist because it will upregulate it where I want to downregulate it without touching MOR.

0 Comments
2024/10/08
10:31 UTC

9

How do LGN cells have receptive fields?

In chaper 10 of "Neuroscience" by Bear, Connors and Paradiso it is said that "by inserting a microelectrode into the lateral geniculate nucleus (LGN), it is possible to study the action potential discharges of a geniculate neuron in response to stimuli and map its receptive field."

As retinal ganglion cells are connected to a spesific area of multiple rods and cones via bipolar neurons, the term "receptive field" is not difficult to understand. It refers to the area on the retina that sends information to a single ganglion cell.

I don't understand how this applies to cells beyond the retina, such as LGN-cells. As far as I've understood, they are relaying the signal from the retina to V1, whilst being functionally organized in the layers of the LGN.

Does a single LGN-cell also "summarise" impulses from multiple retinal ganglion cells similar to how a retinal ganglion cell "summarises" impulses from multiple rods and cones in its respective receptive field?

OR

When speaking of the receptive field of an LGN-neuron, do we actually mean the receptive field of the retinal ganglion cell supplying the ganglion cells.

These are two explanations I came up with, and they contradict each other in the sense that in the first explanation I assume LGN-cells synapse with multiple different ganglion cells whereas in the second explanation each ganglion cell synapses with just one ganglion cell.

5 Comments
2024/10/07
11:16 UTC

7

White Matter Atlas?

Hi everyone,

I was wondering if anyone knows of a atlas that focuses solely on white matter tracts? I'd prefer a hard copy one if possible.

Thanks

3 Comments
2024/10/07
03:03 UTC

6

How much of a role does exercise play in healing peripheral nerve injuries

Can enough exercise be the difference between full recovery and incomplete recovery/chronic pain? Does this depend on the severity of the injury? Cardio vs strength training?

2 Comments
2024/10/05
02:31 UTC

6

Textbooks for understanding alzheimers?

For my drug development research

1 Comment
2024/10/04
16:17 UTC

3

What is the closest physical correlate of consciousness experience? Which neural processes are necessary or sufficient for conscious experience?

While we experience e.g. the color green, there are many different processes happening in the nervous system. Activation of photoreceptors, synthesis of neurotransmitters, their release into the synapse, their binding to receptors, intraneuronal signalling cascades involving thousands of distinct protein types, ions flowing into and out of the neuron, and much more. Which of those many events are necessary or sufficient for conscious experience (qualia)?

Let's do a thought experiment. We take out all the proteins except for the ion channels, and replace all chemical synapses with electrical ones, thus eliminating the need for neurotransmitters. Take out all other cellular components as well with the only thing remaining are the cell membrane, the ion channels, and the ions, so that action potentials are still possible, creating an "action potential-only brain". Would the influx and efflux of ions still give rise to the conscious experience of the color green? Or would it be a philosophical zombie, functioning exactly like a human but not experiencing anything? Would all the other cellular processes be necessary for conscious experience?

Intuitively I would say that such an "action potential-only brain" would be both necessary and sufficient for conscious experience, just because the electromagnetic fields created by the movement of ions seem to me more "consciousness-like" than any of the other cellular events, e.g. phosphorylation of NMDA receptors. Quantum mechanics seem even more "magical" and metaphysical to me and thus a possible candidate for the physical origin of consciousness. Though I have zero evidence to back this up. It's just my intuitive guess.

I don't think we will ever be able to fully explain consciousness (hard problem), but we can get closer and closer to its physical origins (easy problem).

What do you think?

19 Comments
2024/10/04
13:45 UTC

0

Any idea?

Does anyone know why it could be that since taking Olanzapine I no longer feel my muscles when i work out or have a massage, and I no longer feel my stomach digesting or rumbling when I'm hungry?

0 Comments
2024/10/04
08:35 UTC

20

Understanding Pain and Pleasure in the Brain

Without getting too deeply into the philosophy of consciousness, what is understood about pain and pleasure at the neurobiological level? As a layperson, I get that pleasure (or positive experiences) is associated with neurotransmitters like dopamine, while pain (or negative experiences) typically correlates with neurotransmitters like cortisol. However, beyond these neurotransmitters, what differences exist in the electrical signals of the neural cells themselves?

17 Comments
2024/10/04
03:25 UTC

1

Best labs/unis for a neuroscience PhD in the UK

Hey everyone,

I’m considering applying for a PhD in neuroscience in the UK and wanted to get some insights on which universities or labs are considered the best for this field. I’m particularly interested in dopamine and it’s role in movement, but I’m open to suggestions from other areas too!

If you’ve done it are currently doing a PhD in neuroscience in the UK, I’d love to hear about your experiences - both the good and bad. Some things I’m curious about:

  • Quality of supervision and mentorship.
  • Lab-culture and work-life balance.
  • Funding opportunities.
  • Cutting-edge research in neuroscience.
  • Opportunities for collaboration (e.g. with industry, other universities, or international projects).
  • Any notable research groups or PIs to check out?

I’ve heard great things about UCL, Cambridge and Oxford, but I’d love to know if there are any hidden gems that don’t get as much attention. Thanks in advance for any advice to recommendations!

6 Comments
2024/10/03
23:08 UTC

3

Céline Dion’s Doctor Keeps Her Eye on the Prize: Advancing Medicine

On this episode of Health Science Radio, CU Anschutz physician and researcher Amanda Piquet, MD, explains stiff person syndrome (SPS) and discusses an upcoming clinical trial that will examine whether chimeric antigen receptor T-cell therapy could improve the gait of SPS patients who struggle with walking. While this year has taken her to new heights, she remains grounded in her desire to advance therapies for patients with rare neurological disorders.

Amanda Piquet, MD

0 Comments
2024/10/03
21:54 UTC

1

What AA is more applicable for transferring to uni for univeristy

Currently i’m in community college here in CA and i’m striving for a possibility to transfer to a UC for neuroscience. However, i’m listed as a “psychology” major. Does it matter if i’m either a “psychology” major or should I switch it over to biology?

0 Comments
2024/10/03
20:17 UTC

3

Current Psychology/biology major interested in a neuroscience PhD

Hi, I am a current junior psychology and biology major and thinking about grad school. I am in 3 psychology labs and looking to add a neuroscience lab before I graduate. However, I have heard several horror stories about grad school and how its not worth it. I will be perfectly honest and I only really started this this neuroscience goal last semester, before I was planning on neuropsychology, so I am not exactly sure what jobs are available for a neuroscience master's vs a PhD. I have considered taking a gap year, however, the amount that is paid to psychology/neuroscience research is just around the same as a stipend would be for some of the graduate programs I am looking into. I was curious if you all had any advice about grad schools or other potential options I should look into. I have considered other options related to neuroscience such as a a trade school in neuromonitoring, however, I wouldn't really be using my bachelor's or research experience. Thank you!

2 Comments
2024/10/03
18:09 UTC

7

The Neuron, the Synapse, and the Connectome

1 Comment
2024/10/03
15:36 UTC

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