The last few times I've tried it, I had bad trips and had to stop it with Seroquel.
I got it in a spray form. I tried to control the dose by pressing the spray more gently, but it didn’t seem to work—it just released the same amount of liquid each time.
I've had it hidden for a year, and the plug told me that each 'spray' contains 5 mg, so I guess I have to trust the plug on that.

Have a medium tolerance, currently on a break, takes 350mg or so of K for a deep hole, doesn’t last long enough though

For $290 I can get 14g K or 2g DCK or 2g DMXE(or 1g each). If I’m mainly interested in holing, which of those would give the best experience? I’m leaning towards DCK as I’m already experienced with K and for $290 it doesn’t seem like DMXE is worth it considering the higher dose/shorter length than DCK. Can you hole on that DCK even? I’ve seen reports saying you can and it’s more impressive than a K-hole vs others saying you can’t and just blackout. Still want something I can use at lower doses occasionally too that’s not boring

Title

Curious how long 3-ho-pce takes to kick in if taken orally? Is there a preferred ROA or is oral the best way to go. What’s the onset and peak timeline like?

In terms of a drug test

i have access to memantine and i had a friend who’s taken it and loved it but im not trying to trip for days straight. my favorite part about ketamine is that it lasts only 30 mins and i dont really get a hangover from it past 2 hours. anything similar to it that wont destroy my bladder other then dxm?

Hello dear reddit, I'm experienced user of various chemicals, different benzos, LSD, shrooms, morphine, methadone, deliriant, weed, I know my medicine pharmacology I'm 4th year medical student, if it's available in pharmacy, hospital or dealer/plug, I have tried I also know advanced organic chemistry, I make my own distilled wax from weed and also edible, can make harmaline 99% for mushroom, can tolerate 900mg of dxm and reach 3rd platue

I also know antidotes for almost any drug. Before med school I studied clinical laboratory science and clinical biochemistry

I'm 71kg, 178cm, I work out regularly, eat healthy

Two weeks ago I got 7.5g of ketamine for the first time and I went on IM and IV Binge, all in all I was having a blast. No side effects. Doing well, even using it LSD

Then after the binge was over I got a latest strain of COVID-19, pretty strong and started pissing semi red(haematuria)

So I was wondering is this ket bladder toxicity or because of virus? I was feeling semi dead for three days. Do note I was feeling semi dead from virus effects. So it was pretty strong

TLDR: went on heavy 7.5g ketamine IM/IV infusion binge then afterwards caught a very strong virus from hospital, started pissing blood. What's the reason?

Fairly experienced with K, enjoy both small doses and hole doses. Might try 3-ho-pcp soon, how does it compare?

From what I read, it’s similar to K but a bit different. It seems like it’s less sedating, harder to dose, more manic.

I usually insufflate a total of 200mg K over 2-3 hours (medium tolerance). How much 3-ho would be a good similar dose? 5mg? How is it different from K? Some say it’s completely different and others say it’s very similar.

How is using 3-ho-pcp and K together? Can I use it to get more out of my K?

I also like using K as a psychedelic combined with weed to get visual K-holes. How are high doses on 3-ho? Is there a hole like state on 3-ho? How do the visuals/headspace compare? Any reason to combine the 3-ho with my normal K-hole dose?

You can use magnesium or agmatine to potentiate K slightly. Can you do the same for 3-ho and are there any negative effects?

When I take drugs (dxm, dph, tramadol etc) I feel that a version of me improves, it is like the me that I always wanted to be, more sociable, outgoing, charismatic and I even feel that I am another person and that everything around me changes Next to me, I feel that people are different with me, they interact with me more, they laugh at my jokes when I tell something, it's all so fucking strange, because I always feel that everyone changes with me for the better when I regain my full consciousness the day after being doped , everything is so nice after getting high, and it's not so bad being sober without anything on me, but when I'm in my world everything is magical.

The other version of me likes French music and the one that is in Portuguese, he enjoys it a lot, on the other hand, my sober self doesn't feel the same listening to it without something on top, my other version loves to eat, he doesn't feel guilty about anything, he loves being alive and even seeing everything purple in the trance, she greatly appreciates listening to every detail of her surroundings, every sound, she loves to breathe deeply and feel the textures of her bed.

It's weird because my sober self is a little reserved, I would love for her to be the person I am on drugs all the time... I mean, all the time.

This is something I've always known since I took drugs but I wanted to talk about it, does anyone have the same or similar feeling?

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I saw a post on here a while back about using sarcosine (which upregulates nmda activity, aka a sort of nmda agonist (dxm and other dissos are nmda ANTagonists, as I’m sure all of you know)) to reduce tolerance. I’ve also seen posts about racetams, such as piracetam to reduce tolerance as they are also nmda agonists. I started researching sarcosine because I am a victim to permatolerance from being dumb and binging for days in high doses. I found it to be the most easily accessible and decided to get some. I’ve taken 2g (4 500mg capsules) a day for around a month now, and just took 600mg of dxm hbr robotablets around 15 minutes ago. I will update on if my tolerance was successfully reduced or not as before 600mg would not feel like much for me due to tolerance. If my tolerance was successfully reduced I will be making sure to follow the week per plat rule from now on. Wish me luck.

Update: it most certainly lowered my tolerance, I don’t think 600mg has ever hit that hard before even when I didn’t have a tolerance.

I don't understand this chem. Other dissociatives work as expected, with the usual degree of subjectivity. I have low-moderate disso tolerance, but even the less dissociating ones like 3-Me-PCPy give me typical dissociation.. but 3-MeO-PCE feels strange as fuck - it definitely does something, but I can't put my finger on it. Those are the effects I get with it, dosing between 5-25mg always IN :

• Color enhancement
• Anxiety suppression
• A strong tendency to be more "in the moment"
• Hypomania or increased verbal fluency, not consistent.

There's a couple other effects I'd have a hard time explaining but that's about it. 3-MeO-PCE 100% does something to me, but it's like a.. non dissociative disso ? If I take other ones in the ~8hrs after a dose they're potentiated (especially CEVs), tried with DMXE 3-Me-PCPy and MXiPr. Again, I know how less dissociating dissos feel and that's not at all what I get with this weird ass molecule. My source is mostly one NL supplier but I got the same result from another vendor, tho both batches looked about the same. Likely made by LL. I sent my first order for analysis, they couldn't measure purity but it came back as 3-MeO-PCE only.

Anyone with similar experiences or any insight ? This is crazy.

I want to try this. Anybody have experience with this stuff ?

As someone who has finally gotten the chance to do both, I think both are good in their own ways but I like K a tad more. I just wanna get the thoughts of what you guys think.

NO SOURCING JUST COMISERATING The china ban on fxe has cramped my style. I'm too old to be digging through onion fields for dissociation. Love to commiserate with others...

(Weed and ket)

So i've recently been experimenting with tiletamine and overall this substance is quite amazing but also needs to be respected and not to be over used or abused.

It is very potent, a low or no tolerance dose is like 20mg its easily 5x more potent then ketamine. The hang time and peak is very long it's one those drugs that doesn't require redosing and I actually dont suggest it. You will hole very easily on this, it's very warm and can be very visual especially closed eye and last way longer then most ketamine or ketamine analogues i've tried.

Cons: If you use high doses or use it multiple times a week it can and will leave you with extreme shakiness in the body mostly hands and legs, not restless but like you feel like you have Parkison's. I experimented for 4-5 days ranging from 20mg to .1 and I had entire week of crippling shakiness like couldnt even hold a fork,

Suggestions: Wonderful substance, not very recreational like ketamine or FXE but if your one who likes to hole and for a long time tiletamine is absolutely king, but it should only be used maybe once a week if that, the rapid tolerance build up is insanse and the shakiness is not fun. If it's used responsibly its a great rc if its abused your going to regret it, also caused my vision to be blurry and its was hard to focus, like looking at my phone and then looking up at something else was like my eyes couldnt adjust properly, which also got better over a few days.

Happy to answer any other questions.

A certain vendor who has a hefty minimum order is selling both DMXE and 3-HO-PCP, and I cannot for the life of me make up my mind as to if I want to get 2g of DMXE, or 1g of each.

Many people here say they love 3-HO-PCP, but it seems just as many think it's a total waste or worse! I loved 3-MeO-PCP back in the day. Is this similar at all? All I have to compare it to is ketamine and DXM (respectively: fun raving and holing, and weird and not interested in trying again).

Looking to get into dissociatives, but I'm not sure which is the best to try first. I have some experience with DXM (300-500 mg doses) and extensive experience with psychedelics (tryptamines and lysergamides primarily), but besides that I've never tried any other dissos. Ideally I'd like something that I can use with oral, smoked, or vaped ROA.

Anyone remember binging about a gram a day for a month straight... those were the days. !!

I remember it being so cheap, I would sniff huge lines & chew little crystals all day long. Get a good night sleep, & wake up early to start it all over again.

For me it's an almost (keyword, almost) perfect mix of psychedelic healing/exploration/recreational potential as well as the therapeutic benefits of being dissociated enough to confront certain things that may be very difficult without some anesthesia.

I feel like the first time I took dxm it was magical, I did it with a whole syrup and 12 capsules of tramadol, I literally saw the sky, everything was purple and I even had very real hallucinations and felt the music.

Yesterday I checked reddit and decided to try dxm again and to my bad luck it was not as magical as the first time, now I have an internal void of wanting to consume a little more than I can bear so I can feel something in me that I have not felt before . Before, I have the post-consumption feeling LOL but I don't feel happy.

I stopped using because I didn't have time to rest... after using I need to recover my mind after exploiting it

No further explanation

NO SOURCING ALLOWED just the question and the answers. are these chems available for our american residing residents? im in the northern section of the continent, were all our pcp analogs have been officially banned, my vendor been out of opce for over a year now. that said are you guys still able to research in the year of our lord 2024? remember please dont break any rules, sourcing is completely banned by reddit, dont be an idiot in the comments and just answer the asked question

Got myself a bag of ketamine some time ago and snorted it a couple of times. When I took higher doses I felt very inebriated and was barely able to move. I also had that thing where it was impossible to keep the eyes pointed on one spot. But I felt nothing that could be described as dissociation. Is it possible to be immune to the dissociative effects of dissociatives? The Ketamine was lab tested and was in the form of needle like shard crystals.

V