If I have 3 follicles 23mm,21,19mm after trigger on day of IUI 1 egg was released what are the chances other 2 follicles will also be released or not ? Can anyone explain how does it work. I did medicated cycle with letrozole and Fsh injections

I started metfromin around 3 weeks ago and I've just started my period. Is it too soon to notice any changes this cycle? Also what changes to your cycle did you notice with metformin?

I had great success with ovasitol for managing my PCOS symptoms. My ob told me I needed to go off of it for TTC, so I did. Then I looked into the research and it seems like there are benefits for people TTC with PCOS. I reached back out to my ob and said I would like to resume unless she has major concerns and she replied “big no on ovasitol because it messes with your metabolism”

I’m probably going to fire her and am planning to get a second opinion because I feel like she has been dismissive of PCOS symptoms. Am I over reacting? Is this weird? I’m freaking out that I’ve lost the progress from a year on ovasitol during the time I need it most.

Not asking for medical advice.

Hi y’all I’m 26 and I guess now a member of this sub… My bf and I were trying for a baby all last year and it didn’t happen. We took it as a sign and he decided to enroll back into school and we decided to pause and try again in 2 years when he finishes (important to mention bc we just lost 2 years of precious time to TTC while he’s in school) I’ve been having crazier than ever symptoms and decided to go to a doctor. I always suspected PCOS so why does my heart feel so heavy now that it came out of a doctors mouth. My dream was always to have four kids and now I’m being bombarded with stats about how my pregnancy in the future is going to be considered high risk and that although many women with PCOS go on to have healthy and normal pregnancies, I still have to be cautious and aware of the potential severities that my body will face during my pregnancy later on. I feel my whole world just falling apart, I know everything will be fine and I will be blessed with a baby when God says the time is right. It just makes so much sense now why I couldn’t have a baby last year no matter how hard we tried I’m really sorry for this long post. My heart just feels heavy and I feel like no one understands me right now. My boyfriend has been doing everything to comfort me through FaceTime. I still just feel so alone. Even though I know everything is gonna be okay, I can’t explain why my heart feels heavy. Why can’t I stop crying about this. It’s not a death sentence or anything so why does it hurt so bad to hear this news

Read a good book lately? Pets do something cute? Do you want someone to cheer you on because you have a big presentation at work next week? Share it here in the chat thread!

In the TWW? Got some symptoms you want to share with others in their TWW? This is the thread for you! Share your symptoms and don't forget to update the BFP thread with your result!

This was our second IUI cycle. I had my first hcg blood draw 2 days ago at 14 DPT and 12 DP IUI. Results came back at 1.9. They had me come back today (16 DPT and 14 DP IUI). The result is now 2.8. The clinic has made it clear this is not a viable pregnancy but they still recommend I continue my progesterone/estrogen pessaries and come back Monday for another hcg blood draw.

I’m just confused as to what I should expect? Is this considered a chemical? Why do they recommend continuing the estrogen and progesterone if this isn’t viable? I’ve never had a hcg >1 before so this is new to me. Any answers or experience with this would be greatly appreciated. Thank you all for being a part of this community ❤️

Hi all! I posted a few weeks ago regarding my mission to TTC and asked everyone for advice. I know I am incredibly lucky that it has happened so quickly but I started my period yesterday, after not having one for 15 months! For two weeks I have, slept 7 hours at least each night, ate ‘mindfully’, taken my supplements and made sure I’ve got my 10k steps in each day.

TW: mention of chemical pregnancies Hey everyone! I just had my annual today and it’s the first one I’ve had since beginning my TTC journey. I have had 3 chemical pregnancies since about 2019, but none of them I was actively trying at the time. I’ve been seriously tracking my cycles with CM, BBT, and LH strips. I noticed and told my doctor that, I seem to ovulate once every 90 days, but I get a breakthrough bleed on months I don’t confirm ovulation. This is day 50 since my last confirmed ovulatory cycle ended. However, on Monday I felt like my ovary and fallopian tube were being twisted into a knot, then that night I had a bit of bleeding and have been spotting ever since. I did not confirm ovulation this cycle so it’s definitely not my period. She is sending my for a pelvis ultrasound in a few weeks and for my first fertility consultation. We’ve only been trying since August, but I’ve only confirmed ovulation twice since seriously TTC. Additionally, I noticed my luteal phase is only 9ish days long. I don’t know that I have a point with this post other than just feeling pretty annoyed by my body. I knew I’d have difficulty ovulating because I’ve been diagnosed with PCOS since I was 16 and I’m 31 now. What specifically should I ask about/bring up on my first fertility consultation?

The uterus is anteverted and measures 6.35 X 4.11 X 4 Cm with an endometrial thickness of 12 mm. No obvious focal myometrial lesion is seen. The ovaries are normal in size and texture. Rt. ovary : 3.74 × 2.92 x 3.69 cm With simple cyst measuring 34 X 36 mm Lt. ovary : 3.99 x 3.92 x 3.5 With simple cyst measuring 30 × 32 mm

TTC. Had two miscarriages 2022 and 2024. Taken metformin&letrozole before to help me ovulate. New OB did not give any medicine. She say any medicine won’t make me ovulate as long as I have cyst. She is pushing me for ovarian cyst drilling. Should I get a 2nd opinion? I feel confuse as she makes me feel it’s my last resort.

Hello!

I have PCOS, but I've always had regular periods. I was diagnosed based on cystic ovaries, insulin resistance and blood work.

I have one kid that took us 4 years, and eventually the sling shot method worked.

We've been TTC for going on 3 years now with 2 early losses. The insurance I had those years didn't cover any fertility treatment at all so we were just doing ovulation tests and timed intercourse.

I started 2.5mg Letrozole in December, my OB prescribed it under irregular periods so I didn't have to wait another month. Then January I went to 5mg and tonight I'll be starting 7.5mg. The first round I ovulated, and I'm doing my ultrasound for the second round in a week.

Before all this, I cut out caffeine and alcohol, started doing all the right things, my husband even quit drinking alcohol and switched to boxers.. We have sex everyday starting the day after my period ends and 2/3 days after I ovulate (if I ovulate)

I didn't try Letrozole last time, and I read so many success stories about it that I started to get hopeful again, and now I'm starting to get discouraged.

I don't really know what I'm looking for, advise? Success stories? To vent?

I'm just getting sad and need some hope again.

Thanks!

After ttc for 2 years I was finally prescribed letrozole and was able to start my first round this week. I'm starting on 5mg. I'm so excited and I wanted to share because I'm feeling really good about this. I found out I had pcos and a small tumor on my left ovary last February and my doctor at the time prescribed me like 12 pills of clomid and basically said good luck. I left his office and cried in my car because I felt like he genuinely new nothing about PCOS and I was left with so many questions. To be honest, 3-4 months after that I felt like giving up and honestly I did. But this passed month I've turned over a new leaf and just feel like I have a burst of energy with hyper-focus to try again and I'm just hoping for something positive. ✨️ Baby dust to everyone ✨️

Hi! Back in October I was officially diagnosed with PCOS. My free and total testosterone came back as 79. I’ve had very irregular periods and ultrasound confirmed polycystic ovaries. Never tested DHEAS

I am now reevaluating my PCOS with a different physician as I have moved. Periods are still very irregular and ultrasound is scheduled but my total testosterone came back at 30. DHEAS is still awaiting.

How could my testosterone have dropped 40+ ng in four months? I know it’s good to be back in the normal range but was curious if it dropping this much this fast was a cause for concern?

If it means anything, my vitamin d is very low lol. HDL is high

Read a good book lately? Pets do something cute? Do you want someone to cheer you on because you have a big presentation at work next week? Share it here in the chat thread!

In the TWW? Got some symptoms you want to share with others in their TWW? This is the thread for you! Share your symptoms and don't forget to update the BFP thread with your result!

This is going to be long, anyone who reads through I truly appreciate. I guess I’m looking to vent but also wondering if anything similar has ever happened to anyone. So I had my 5th IUI on Saturday the 18th at 11am. Nothing out of the ordinary (my cervix had been difficult to “get in the right position”) other than that we walked out and went about our day. My husband works 7pm-7am so I do dinner and bedtime, relax then go to bed around 10pm. The next morning I am woken up around 5:30am with a crampy stomach feeling then within five minutes I am calling my husband to rush home because I am in the worst pain I have ever experienced. My entire abdomen is just on fire and throbbing and not letting up. My husband zooms home, sees the state I’m in and immediately calls 911. My white blood count was 13 and elevated lactic acid so they figured infection but didn’t know of what, I had a CT, multiple ultrasounds, a HIDA scan (gall bladder), an X-ray, and lots of labs. NOTHING was out of the ordinary. A had a little bit of fluid around my liver/gall bladder but drs did not think that would cause so much pain. I spent four days in the hospital, and went home with no answers and some antibiotics. I hate to blame my RE but what are the odds? Is this just a wild coincidence from the IUI? I was also devastated because this was my last IUI, I told myself five and to just let it be. All those tests and medications can’t be good for any of this process. Thank you for reading, I am already so mad at my body for having PCOS, but then not this freak situation is so upsetting.

Side note I am 36

We just got a big fat negative again. We’ve been trying for 14 months now, and this was our third IUI/letrozole cycle. This time, I was ovulating two eggs, and we were feeling so hopeful.

My grandmother is terminally ill with cancer. And this week, we received the news that my father-in-law’s cancer is also incurable. We just really wanted the chance to tell them that they’re going to have a grandchild/great-grandchild. But I’m afraid we won’t make it in time. I’m devastated.

We’re continuing with IUI, but my expectations are low. I’m really considering if IVF might be a better option.

I’ve had 4 medicated cycles and one IUI medicated cycle.

had the test come back negative today.

I’ll be doing one more IUI but mid cycle my doctor sounds like she’s going to recommend IVF instead during our follow up appointment. She originally wanted me to start with IUI but we did medicated instead.

Im turning 29 in April and I am overweight. I know that for any anesthesia needed procedures it’s going to be more involved.

I had lost 70lbs with wegovy earlier last year. It may have been the weight loss (but even when I was very active and healthy weight I didn’t have normal cycles) but from 1/2024-9/2024 I had regular cycles for the first time in my life. Then they stopped so I had to do medicated. This was around the time where I was off wegovy and gained 15lbs back. :(

I’ve since held steady gained/lost around this 10lbs or so. Healthy eating and activity is a work in progress but a focus.

Has anyone had success with this progress of treatment?

Thank you 💚

I (F36) just failed my first cycle after Letrazole/Ovadril shot fertility treatments.

I had 4 negative pregnancy tests this morning after my two week wait.

I’m heartbroken and really just trying to keep hope alive. I am not even sure if my body will give me a normal period so I can start again.

Also my friends all suck and I have zero supportive people in my life. It’s just me and hubby trying to navigate it all alone ☹️

Any encouragement is appreciated

So for backstory I had a 11w MMC last year due to Turner’s syndrome and needed a D&C. I gained 10lbs while pregnant & 15lbs after from depression. After my D&C my periods were lighter than usual. They used to be 3-4 days & are now 2-3 with only 1 heavy day but no other symptoms not super cramps or anything, also not successful in conceiving.

I went back to my dr’s and they did an ultrasound which showed good uterine thickness but enlarged ovaries and many follicle cysts. She ran other tests, thyroid, progesterone, & insulin resistance. Everything came else back normal.

I have other symptoms of pcos such as facial hair, long cycles, high lh levels & unpredictable later ovulation. But my doctor doesn’t believe I have ashermans or pcos, she thinks I have just been under a lot of stress and just to give it more time. We’ve been trying around 6-7 months after the miscarriage. Just looking for an advice on your experiences

I'm a long-time lurker, first-time poster! Seeking advice/commiseration.

I'm 30 and do not ovulate or get a period on my own (I had an IUD until Feb of 2022). I have PCOS and am not interested in weight loss - I have found a great RE who takes a Health at Every Size approach.

I'm in my first cycle of IUI, technically. We used Provera to induce a period, which started January 3rd, and then did a course of 7.5mg of Letrozole with no growth of the follicles but some growth of the endometrium (6.46 on Jan 10th). My RE had me do another round of 7.5mg (no growth) and then 10 mg (no growth as of today and endometrium down to 4mm). I'm curious about what people think the next steps could be based on their own experiences with their REs. I'd also love to hear if anyone had similar experiences and were given helpful explanations from their doctors or nurses. My clinic is good, but it's hard to connect with the doctor because the nurses are the messengers who call with results and next steps.

Thank you so, so much for any help or response! I'm very grateful for this community right now.

AMH: 13.44
Meds: Metformin 2000mg // Supplements: Berberine, Alpha Lipoic Acid, Magnesium Glycinate, Vitamin D, Vitamin B12, Prenatal + Choline, Coq10, Ovasitol

Currently on CD 40. I confirmed ovulation on CD 33, but I’ve NEVER ovulated this late or had this long of a cycle.

I usually ovulate anywhere from CD 14-21. I guess cause my PCOS?

My hormone levels were out of whack a few months ago. I changed my diet and life style. I got a blood test two weeks ago and all of my levels are now normal. I was so happy and optimistic about this cycle and now it’s the longest cycle I’ve ever had when my body is in the best shape It’s been in a long time and I’ve worked really hard to get here.

I did manage to BD a few days before ovulation but not feeling very hopeful and I’m really sad and exhausted with this process.

I see my RE next week. She wanted me to get in better shape and try on my own for a while. I am almost at the year mark where I’ve been trying after loss and wondering whether medication(Clomid, letrozole, etc) or an IUI would be the most effective method. I ovulate on my own and my husbands sperm is average. Would really appreciate input!!!

Read a good book lately? Pets do something cute? Do you want someone to cheer you on because you have a big presentation at work next week? Share it here in the chat thread!

In the TWW? Got some symptoms you want to share with others in their TWW? This is the thread for you! Share your symptoms and don't forget to update the BFP thread with your result!

TW: loss

My husband and I have been trying for nearly two years and sadly had a chemical pregnancy after our second IUI.

I’m trying to stay positive and look forward to future cycles atm. I asked this question in the TFAB subreddit but I feel like this might be a better place to gauge for those of us who have irregular periods without medication.

For those of you who either had a CP or just stopped letrozole after using it for a few cycles, what was your next cycle like?

I’m not sure which subreddit to post this in, so I’m cross-posting.

I had PCOS, and I completely reversed my symptoms by following a strict keto diet, intermittent fasting, and regular exercise. I lost 18 kilograms, going from 85 kilograms to 67 kilograms. In December 2022, I got pregnant, had a C-section in August 2023, and my LO is now 16 months old. Throughout my pregnancy, my weight increased so I’m currently back at my pre-keto weight. I’m trying to lose weight again, but it’s much more challenging this time because I’m not following a keto diet. Instead, I’m focusing on eating wholesome foods and exercising regularly. I’m still breastfeeding my LO 2-3 times in a 24-hour period, primarily before naptime and bedtime. It’s been over two years since my last period in November 2022.

My partner and I are considering want to start trying again for another baby. I understand that I haven’t had a period since 2022, but can I still get pregnant? Do I need to lose weight for my periods to return, or is it the breastfeeding that’s the issue? There are so many factors to consider right now, and I’m trying not to dwell on how I lost weight before as that approach was unsustainable and depressing for me to maintain. Any advice or guidance would be greatly appreciated.

Hey. I'm 27, diagnosed PCOS, normal BMI. I came off the pill last year in May to start TTC #2. I had 5 cycles that were 33-37 days long, which was amazing because I had never had regular periods ever in my life before then. I used OPKs and BBT to confirm ovulation successfully. The only concern I had was that my luteal phase was shorter than when I was TTC #1 (11-12 days rather than my previous 14 days).

Skip forward to now and I am currently CD94, roughly 60 days late. Typical, because I decided not to track ovulation this cycle, instead planning to start tracking again in the new year. Negative pregnancy tests every couple of days since before my period was even due.

I have been trying for 2 weeks now to get a doctor's appointment, with no luck. I'm UK based so don't have an OBGYN. Is there anything I can do to bring my periods back? Any advice?

Read a good book lately? Pets do something cute? Do you want someone to cheer you on because you have a big presentation at work next week? Share it here in the chat thread!

My husband (29M) and I (30F) have been TTC for 2.5 years. We had our IUI done yesterday and I can't stop overthinking. This is our first IUI cycle and first time to have positive OPK ever since though the doctor did not confirm ovulation before IUI.

For context, our protocol was Clomid 50mg on CD2-6, injectables on CD7-9, trigger shot on CD11, IUI on CD13.

Prior to that, I made sure to make lifestyle changes for more than a year, gave up coffee and I managed to lose 11 lbs in 6 months with the help of metformin ER and my BMI is now in normal range. I know 11 lbs is not that great but I was struggling to lose even 2 lbs without it. I have resigned from work to lessen my stress and now I have nothing else to do during TWW and it's stressing me out. I did not feel any cramps or nothing after IUI. We're still feeling hopeful but I'm worried still. How do you cope during TWW?

I don’t understand why this has happened to us (35F, 30M). I worked so hard to lose weight, to watch what I eat, to take care of myself mentally and physically. We moved to a bigger place, started saving money. We planned this baby only to lose it to an ectopic pregnancy along with my right tube a few days ago. I feel so hurt and hopeless. Like why me!? I wanted nothing else but to be a mom. My left tube has some scarring so my OBGYN says I have to see a fertility doctor to assess and see if it’s even good to try again if not my only other option is IVF. I am about to be 36 and have PCOS. I just feel like that was my only chance. I am still grieving my loss. My partner has been so supportive and I feel like I’ve failed us both. I know I could have died, that I am lucky and should be grateful to be alive. But right now that doesn’t lessen my pain.