In the dream, this company was exceptional at marketing and made smokeable nootropics. They were blunt sized and I have no idea what exactly was in them, but you smoke them in the morning for energy and focus. They had a huge variety of flavors, one was even just called "heroin" and apparently could help you quit. You could also select a filter for what type of effect you desired. Sunlight was a huge problem though for some reason, it was extremely dangerous to get a lot of sunlight while you used the product. One of them was to be used at night and was a sort of bedtime blend that relaxes you.

Is it possible to make a nootropics blunt and is this the business idea I have been searching for?

I seem to be sleeping bad after taking pterostilbene. Harder for me to fall asleep, and waking up very early, like almost in the middle of night with a mental clarity. Can’t fall asleep again.

Very strange since I don’t read anything about it negatively affecting sleep. I have the same effect with resveratrol.

Tested this many periods of on and off, always same effect when I start again.

Anyone also experience this or has any advice? I want to keep taking it but after a week I feel exhausted. Dose is only 50mg.

Title And any advice is much appreciated

For sublingual absorption, I’ve read that anywhere from 2-5 minutes of holding substance under tongue is enough.

I was wondering is there any absorption happening after 5 minutes? Does longer= more effective? Would I absorb more if I held it for 10 minutes as opposed to 5? I’m having trouble finding any answers on pre-existing threads, or on google, so that’s what prompted me to make a post here.

I’m just trying to get the most out of my product. I also read that holding the liquid between the gums & lip is effective as well, or should I just stick to under my tongue?

Any insight/ personal experiences would be greatly helpful. Thank you in advance.

Do we know the differences in pharmacological action? Are any of them better for anxiety-prone people in comparison to caffeine?

Ive had an issue, where I ordered 10 grams of something, they sent me a 2 gram package. I did the whole contact us thing, they responded quickly, I sent them pics as requested, then was ghosted for a week. I even sent emails daily in the same email chain and no response. I'm pissed, that's a lot of money, and I'm not going to open the package yet, incase they want it sent back in exchange for the right size, so I'm out the money and the product right now. I even started another new complaint with no response this time. Been over a week.

I know supplements that are gaba agonist are a bit controversial so wondering what the general consensus on gaba is and it’s potential for tolerance / Withdrawl…

I ordered the “normal” selank but after ordering I saw that they also sell N-acetyl Selank. Is there any advantage for normal selank, or did I just mess up.

Hi, Today was very sad as I found out that Purenootropics will be discontinuing centrophenoxine.

For me personally, as someone who has benefited from centrophenoxine as a replacement for dmae for the past 4 years its sad to see a good product being sun-setted .

Does anyone know why pure nootropics is discontinuing centrophenoxine?

Has anyone compared both substanced for anti depressive effects?

I trialed sarcosine in september and it was awesome for depression, but now its been out of stock for a long time and only US suppliers left.

anyone tried indiamart to order this stuff ? do they provide domestic delliveries?

(not asking for sources in the post, but if you have some please drop a pm)

GABA Does Cross the BBB Indeed!

For years, the consensus on this forum was that GABA,

• the most common inhibitory neurotransmitter in the central nervous system
• that plays a role in mood and emotions, as well as feelings of relaxation and calmness,
• that can enhance sleep cycles

does not cross the blood-brain barrier (BBB).

However, many users who have taken GABA supplements have felt that this couldn't be accurate based on their personal experiences. Fortunately, recent research has provided evidence that GABA can in fact cross the BBB. However, it is well-known that GABA has relatively poor bioavailability on its own.

​

Improving GABA's Bioavailability & Effectiveness

Given this context, let's share our knowledge and experiences regarding supplements that can be taken alongside GABA to increase its bioavailability and effectiveness.We are not looking for supplements that are known to independently increase GABA levels in the brain, such as Phenibut, Valerian, or Lemon Balm. Rather, we are interested in learning about compounds that can be co-administered with GABA to enhance its absorption and utilization.Some potential examples may include:

• Supplements that can facilitate GABA's permeability across the BBB
• Delivery forms of GABA that improve its bioavailability
• Nutrients that have a synergistic effect when combined with GABA

Sharing Our Knowledge and Experience

List any other co supplement that improves GABA's Bioavailability and Effectiveness

Share your experience

Share the dosages

Share research papers

TWO Examples in the Scientific Literature

​

• L Arginine : nitric oxide production increases gamma-amino butyric acid permeability of blood-brain barrier according to this
• L Theanine : GABA and l-theanine mixture decreases sleep latency and improves NREM sleep according to this

​

​

Their prices are competitive and the site looks legit. I just haven’t seen any reviews for them.

I've read that It's safer to consume L-Tryptophan on a regular basis rather than 5-HTP as the former one eventually gets converted to Serotonin too, But there are researches that say L-Tryptophan competes with other amino acids to cross the blood brain barrier and that It must be taken empty stomach to ensure that it crosses the blood brain barrier, But If one has to take L-Tryptophan in the night how can one be empty stomach and what's even the definition of being empty stomach?

Also what's conflicting is the fact that Body has an amino acid pool that already has accumulated amino acids for functioning even when you don't eat anything, Doesn't that mean L-Tryptophan would not be as effectively be able to cross the blood brain barrier anyways as 5-HTP since there would already be other amino acids present regardless of whether you are empty stomach or not?

Share your experiences with L-Tryptophan and If that even worked for you, What time of the day would you suggest to consume it for optimal efficacy?

Wondering if anyone can speak to the quality of NutriVitaShop. Specifically their bulk items.
I have been looking for some centrophenoxine and they seem to have many tempting bulk options.

https://preview.redd.it/ym4mqxtk6iuc1.png?width=1180&format=png&auto=webp&s=26b7f7748144e26864d39e6003c316c8e28cb8d5

Hello! I just ordered Semax nasal spray — I’m interested in using it for depression and cognitive benefits. The bottle I received is 600mcg/spray.

Does anyone know the ideal dosage for depression? Thanks so much!!

Sorry if dumb question. Couple of posts about it here and a few other subreddits and it’s not clear to me after reading comments, explanations etc. Some (but few) say yes, majority says no.

Once again, sorry if dumb question, I have a poor understanding of this stuff. Thanks for your answers!

Was thinking about taking this, searched and can’t find a definite answer. Can someone let me know please? Thanks!

Agmatine Sulfate is the salt form produced by combining agmatine with sulfuric acid.

I have issues processing sulfur and get sick. Are there any other versions of Agamtine I can take?

I heard a good dose to start is 900mg but on amazon (in germany) I see doses like 12000mg daily,10800mg daily, 6000mg daily, 5000mg daily etc.. isn't that way too much? I struggle to find one that is being sold with a reasonable dose

I am looking for feedback about Cognitive Nutrition products. I recently purchased aniracetam mail-order from a retailer in CA. It’s supposed to be Cognitive Nutrition brand with a trade name of “NeuroSpark”. My concern is it’s in a bottle with a crude laser printed label with misspellings. They no longer have racetams on their website, their contact form is broken and no address or phone number is provided. I did find a Chicago address listed as an apartment number. I also found a phone numb which connected to a generic voicemail box and left a message, but didn’t receive a reply.

Years back I purchased some racetams from them directly, and they were professionally packaged and had a COA available if I recall correctly. They seemed to good quality.

Between the bad labeling and inability to contact the manufacturer(?) I’m concerned about what I got. Anyone know about CN or this specific product?

What would be a good, consumable solvent to use for making nootropic solutions? The obvious choice would be food grade ethanol, but I'm not trying to intake any alcohol.. I've read about DSMO but it doesnt seem like a great idea.. What else could be used?

I saw it can be sold in pills, liquid and the mushroom itself. I would like to which one is the best way to consume and has the best result.

Also, is LM a real nootropic? How much time takes to see its effects?

Im a nootnoob/amature. I never tried any of these things but every month or year I see something that is disproven, proven, and reproven. Is it possible to put a list of the ones that have beem recently disproven or even recently banned even?

I’m experiencing insane neurological issues after too much thiamine in a 24 hour period.

-uncoordinated -issues with my hands - like my fingers can text properly

• issues walking

-respiratory muscle weakness

Anyone ever heard of this? The IV was 48 hours ago. Scared to death I’ve been permanently brain damaged.

So I’m looking at this website for a variety of products and I’m seeing mixed reviews of their service. I’m not sure why I should trust review.io so I’m curious if others have purchased from this service and could attest to their quality of product/service. Are there any other sources (aside from cosmicnootropic) that people would recommend? Thanks.

I took it after food but still have diarrhea after couple of hours. I take dispersible tablets