/r/Nootropics

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Research and discussion on nootropics and cognitive enhancers.

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1

permanent brain damage? let me know pls

been taking lions mane again,every day 750mg (i think)

been taking for 2/3months not missing a day and im noticing a huge difference some good, some bad but my brain fog and short term memory was never this bad. im 16f 120 pounds, unable to go to doctors. possible i have permanent brain damage ? or way way too soon to get it? will not take it again was very silly of me to not do my research. (may be overly worried but would appreciate if u guys tell me if ur negative effects lingered on too long after stop taking etc, and never went away etc)

12 Comments
2024/11/09
21:08 UTC

3

Can L-Theanine Combat Alcohol Usage During Development Stages?

Just stumbled upon this subreddit after reading a post from someone who alleviated their anxiety with the usage of L-theanine. I used to be an alcoholic in my early teens, and was curious if taking L-theanine has helped anyone here with the negative symptoms of premature alcoholism such as memory-loss, poor executive function, and anxiety?

2 Comments
2024/11/09
20:45 UTC

3

Would 9-ME-BC interact with abilify or trazadone in any negative way?

I take a low dose of both, 1mg abilify daily and 25mg of trazadone as needed for sleep.

2 Comments
2024/11/09
19:25 UTC

1

Selective DRIs nootropics?

What nootropics are selective to being a DRI?

There's a few different nootropics that're DRIs but all the ones I found have other effects too

Eg modafinil has histamine effects, sabroxy has gaba antagonism effects , Methylphenidate has other effects

Is there any that's purely/almost purely a DRI?

6 Comments
2024/11/09
19:23 UTC

3

Intranasal Pinealon Experiences

Does anyone have any experiences with intranasal Pinealon for cognitive enhancement? Also considering oral pinealon. Any experiences and dosages for either administration method would be appreciated. I can hardly find anecdotes regarding this substance anywhere.

1 Comment
2024/11/09
18:00 UTC

10

Has anybody here tried ASP-2905?

This seems like an interesting compound that has been studied for potentially treating ADHD according to this study. They also found that “ASP-2905 increases the efflux of dopamine and acetylcholine in the medial prefrontal cortex”, both of which are actions closely associated to attention.

So far I’ve only came across one experience online. It’s fairly easy to find it as there’s only a few posts here mentioning it (not sure if I can link it lol). Also there’s only one source that appears to offer this stuff that I can’t mention here but it’s a reputable source that im sure a lot of you guys have came across.

Feel free to add your opinions/advice on this compound. I look forward to reading any kind of feedback, thanks!

1 Comment
2024/11/09
17:48 UTC

1

Which nootropic could help me?

I feel an irresistible need to sleep in 2pm or in early afternoon in general for A LOT OF HOURS...not just for some minutes or 1-2 hours. For 8 hours most of the times!

Also i cannot sleep after 00.30 am ! I wake up almost always no matter how tired i am or how less i have slept, even if i will go to sleep in 9pm or in 11pm i will still wake up in 00.30 in most of the cases. Its like something happens to me in 00.30 and i wake up feeling overwhelmed for NO REASON. I tried xanax just in case it is anxiety...no its not, it didn't helped me at all to sleep or relax. I am just in tension for no reason at this specific time. In afternoon i am relaxed.

Plus for some reason is way easier for me to sleep a lot of hours (for example 5 hours) at night (and maybe and after 00.30am ) if i have slept on afternoon too. If i have not sleep in afternoon, i will only sleep for 2,5 or 3 hours at night and wake up in 00.30am.

Is there any supplement i can try to help me sleep in 10pm till 6am (normal hours)

3 Comments
2024/11/09
16:32 UTC

4

What is the smell of 9-me-bc?

Just got 1 gram 9-me-bc of an EU supplier, tho I¨m unsure if its the real thing. Smells a bit like brown sugar/liquorice and is super sour. Color is light brown.

Thanks in advance!

https://preview.redd.it/7ehpib8uzvzd1.png?width=928&format=png&auto=webp&s=2429d537a561b9a9e7fdcb4cc0375a88dfbb667e

edit: added pic

18 Comments
2024/11/09
14:18 UTC

1

Bromantane makes me hungry

I’ve been on a calorie deficit for the last 2 weeks, trying to drop a few kcal. Yesterday tried Bromantane in order to improve my workouts and realized I’m super hungry all the time. It wasn’t the case before taking brom. Does Bromantane somehow increase hunger?

4 Comments
2024/11/09
09:51 UTC

3

Lavender oil inhalation aromatherapy and hormone concerns - safe for males?

I'm interested in using lavender oil aromatherapy for depression but have some concerns about its potential hormonal effects. I've read studies linking lavender oil to hormonal issues and premature breast growth due to its effects on estradiol. Since too much estradiol in males can also worsen depression I worry that this aromatherapy might have a detrimental effect long-term.

I would only be using it through inhalation (few drops on a cotton pad, breathing in for about 20 mins daily) - NOT applying to skin or ingesting.

My question: Do these hormonal effects only happen with skin contact/ingestion, or can they also occur through just breathing in the scent? Has any guy here used lavender aromatherapy long-term and experienced issues?

Would really appreciate any insights or experiences.

2 Comments
2024/11/09
09:07 UTC

6

Silajit questions on mood, focus and energy.

I have ordered silajit and Alpha GPC to help with my mental clarity, energy, motivation and overall attention. I have been diagnosed with ADD but since I have a stimulant addiction I prefer not to take the traditional ADD meds and the non-stimulant mess don't work.

What are your views on either for energy, focus, motivation and what not?

4 Comments
2024/11/09
03:31 UTC

7

Any Way of Fixing What I Have?

I'm a 22 year old male and I'm socially inept. I've been this way all my life despite all the countless practicing I've done in and out of work. My brain just isn't adapting and learning. It's really weird, I think subconsciously I don't want to talk. It's like my brain won't fill in the gaps when someone is trying to have a conversation with me, and God forbid I try to start one. It's a mess, I have no clue what to do or say during conversation, and literally 0 interest in it, even if it's something I'm interested in. It's no different even when I try my hardest to be interested, I think it's more of a subconscious issue. It's no different with friends or strangers, I can't even hold a 3 minute conversation with any of my friends or close family, and it's always been like that. Sometimes I excel at talking, it happens very rarely, but when it does, I seem like the most interesting person in the room, and I seem like a much more enhanced interesting and confident version of myself. It kind of comes out of nowhere but goes away soon afterwards.

I don't have any anxiety issues when it comes to talking, I'm not nervous, if my mind decided I can't do it, I just can't. My mind just doesn't give me any input or thoughts to say, I just go blank. I'd like to mention that I've been diagnosed 2 times in my life as having ADHD. One when I was way younger, and one last year. I'm not currently taking any medication for it, which I would heavily prefer not to, I had very bad experiences when I was younger, and if there's an alternative means of treating it then I'll go with that. Mental illness runs in my family, primarily on my Dad's side. I have 4 siblings, all have ADHD, oldest brother also is bipolar, 2nd oldest has Asperger's, and youngest has high functioning autism. I'm wondering if this could be a low dopamine issue, or if there's any nootropics or supplements I can take to help this, my mind is like a blank slate. I've been practicing socializing for 6 years and haven't got any better whatsoever, my brain just isn't adapting and learning. Any advice? Are there any Nootropics to help with this kind of thing?

12 Comments
2024/11/09
02:33 UTC

1

Science.bio , shipping times and discounts?

Hey guys you know how much is the shipping time to USA? And any info about science.bio coupons? Thank you!!

1 Comment
2024/11/09
00:55 UTC

58

Most successful nootropics for anhedonia?

After a big fail with SSRIs for a severe depression, i am currently trying Kanna capsules which seems to help a lot for anxiety but im still struggling with anhedonia... Anyone can suggest anything else?

Currently taking complex vit B, vit D, Rodhiola, and will soon be adding lithium ororate... thanks! 🙏

76 Comments
2024/11/09
00:17 UTC

12

Libido Supplement Ingredient

Background: Male 41 I have a sleep disorder I'm currently being treated for. Awaiting a surgery that should help significantly but till then I'm struggling with numerous comorbid issues. The one pertinent to this post is the sexual/libido side effects of sleep deprivation

I recently bought a supplement from Target in desperation and it actually did something. A very pronounced, definitely not placebo change. I was wondering what ingredient was the most likely culprit. I would love to do more research and maybe just take a singular supplement.

I do not have ED. I have no issues getting hard and blood pressure is good. I also already take Citrulline so I dont think it's the Arginine. It's more desire/libido/energy related.

Ingredient List: Arginine Silica Inosital 1500mg Maca 100mg Asian Ginseng 100mg Epimedium Extract 100mg Black Ginger 90mg

32 Comments
2024/11/08
20:21 UTC

7

Akersunder labs piracetam on Amazon

Hello all!

So I'm trying to ascertain the reliability of this "Akersunder Labs" which is producing and selling piracetam and apparently other products on you Amazon. It looks like the reviews are mostly generally good but there's only handfuls of them for any of their products. I'm concerned about their purity. They say they products are lab tested but can we trust that? What are people's personal experiences with them, and has anyone subjected their products to third party testing?

As it's a lab in China and I can't find too much information about it I feel slightly sketchy about it but the few posts I found about it here were also generally positive and I wanted to see what information any of you might have before I purchase and use any of their products.

Thanks!

13 Comments
2024/11/08
19:34 UTC

6

Experience with Intellimeds?

NSI-189 and Aniracetam specifically?

I dont really trust them that much. But they're the only source of NSi-189 in Europe/UK as far as I know? It's them and Euronootropics. I'm not buying from Euronootropics.

Any experience? and please if you have any affiliation with them state in your answer. Thanks!

8 Comments
2024/11/08
19:29 UTC

16

Vorinostat + Anxiolytics (or other pro-social drugs)

Has anybody tried combining vorinostat with something like phenibut or other drugs that induce positive emotion?

In theory this should ensure the newly rewired emotional response will always be a good one.
Inversely, taking vorinostat and getting buzzed with a shock collar every time you touch an apple should pretty reliable instill a fear of shock every time you see apples.

Something something classical conditioning

11 Comments
2024/11/08
19:09 UTC

4

Help me with NAC acid reflux

Basically the title , i got great benefits from taking nac 1000 but the acid reflix i get for 48-72 hrs is atrocious. What can i do ? Thank you in advance.

13 Comments
2024/11/08
18:47 UTC

8

Agmatine for benzo withdrawal, gastrointestinal issues

I've been taking agmatine to help with my benzo recovery

So far it seems it helps somewhat but the massive downside is gastrointestinal

issues. My stomach gets upset and keeps churning and making loud noises.

Furthermore there's been studies it causes colon cancer in mice studies.

I'm not sure I will continue to take this supplement or at least limit my usage.

10 Comments
2024/11/08
18:10 UTC

2

Reuptake Inhibitors Question?

How is a reuptake inhibitor supposed to actually change your neural patterns when it works by making the neurons that have already fired to fire even stronger, rather than making other neurons to fire?

When ppl say SSRIs are "correcting an imbalance with your serotonin system", isnt it really that those serotonin neurons are great and so you're allowing those neurons a bigger impact on the rest of your brain?

I feel that this is why SSRIs do not work on me, the signals I have running through my serotonin neurons actually suck, and SSRIs enhance the shitty part of my brain.

Same thing with methylphenidate, it disproportionately aggravates my anxiety symptoms and I feel like thats because my norepinephrine neurons are configured to cause anxiety.

8 Comments
2024/11/08
17:01 UTC

18

Why has no-one mentioned the abysmal smell of NAC?

So much people praising NAC for its benefits and functionality, but not once have I read someone say anything about it’s smell. I thought I would suffer for the glory, but it’s just made me nauseous. Let’s hope it will work it’s magic.

It smells like rotten eggs, with a lingering smell and taste once you take it.

88 Comments
2024/11/08
16:41 UTC

21

N-Acetyl-L-Tyrosine (NALT) for Adult attention-deficit/hyperactivity disorder (ADHD)

Hello everyone. I would like to hear from those of you having success using NALT powder for ADHD symptoms. More specifically, I'd really appreciate to know the dosage, times of day, and with/without meal information.

If at all possible, would you be able to state the dosage in teaspoon dosage values? The NALT powder I ordered from Amazon, which did not come with a measuring scoop, states that the recommended daily dose is 400mg daily. That equates to 0.08 of a teaspoon, meaning, just slightly less than a tenth of a teaspoon. Which just strikes me as really low; hence the reason for this post.

While I have attempted my due diligence with reviewing past posts, I cannot seem to garner exact dosages and times of day that folks are using NALT.

Thank you all!

18 Comments
2024/11/08
14:45 UTC

2

NAC & it's effects on Latex Allergy?

Hello all,

I am planning to buy NAC after hearing all the good and bad things about it. I came across a comment recently saying it can increase histamine in the body and can be bad for people with allergies.

I have type IV latex allergy. I take antihistamine meds if I get it. Would NAC trigger my allergy?

5 Comments
2024/11/08
12:23 UTC

1

Are brain scans worth it?

I recently came across a company called connectome that is providing brain scans to test cognitive capabilities such as attention, cognitive load and working memory.

I wondered if anyone had any thoughts or experience of these and if I could use this to figure out which nootroptics I would get the most benefit from? TIA

1 Comment
2024/11/08
10:28 UTC

2

Lion's Mane Headache After First Use

I took half a capsule of lion's mane from oriveda. I had a negative reaction. It was their hot water extract. It gave me a headache, it is calming down now. I never have headaches, ever. This is the first headache I've had that I can remember. What happened? Is it just a bad match for my body? Well it help if I make it into a tea the next time?

4 Comments
2024/11/08
04:33 UTC

3

Does NAC make my brain state similar to when I am meditating? (Thoughtless and distractionless)?

I saw many posts admiring NAC. I have never tried it. What effects should I expect to feel?

13 Comments
2024/11/08
04:15 UTC

8

Is it safe to take a serotonergic 24 hr after taking 12 mg of methylene blue?

If a subject took a dose of 12 mg of methylene blue 24 hours before taking 120 mg of a serotonergic like Prozac , would this cause concern?

Or would it be best to wait 48 hours?

Is there anything to increase the elimination of methylene blue?

10 Comments
2024/11/08
02:57 UTC

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