/r/HistamineIntolerance

Photograph via snooOG

For questions and information about Histamine Intolerance and other Mast Cell disorders. This subreddit is for research purposes only. Please do not take medical advice from this subreddit. If you have any medical issues please visit a licensed doctor.

This community is for helping each other understand diet, symptoms and diagnosis, and discuss ways to live a healthy life with HI.

/r/HistamineIntolerance

22,272 Subscribers

1

Histasolv? 36,000HDU 23$ 30melts

Seems very cheap compared to DAO products. My hidtsmime digest is 20,000kHDU 60caps for 50$

11 Comments
2024/12/01
13:50 UTC

1

food on long hikes/travels

what food could i bring/easily get on long hikes/travels (days-weeks) that's very budget-storage friendly, will last, and will not completely fuck up my HI? i really don't want to give up these activities

1 Comment
2024/12/01
13:11 UTC

2

Anti histamine rebound?

Can this happen?

I was using desloratadine. The first couple days I used it felt amazing. I then noticed I started becoming very off feeling. Irritable. Low mood. Fatigue etc. I've had this with most anti histamines. I kept going a few days and then couldn't cope with the depression feeling I was facing.

I stopped the desloratadine and I was ok for about a day and a half and then I woke with MUCH worse histamine problems. Must have sneezed over 200 times. Eyes are very itchy and sore.

Can you get a rebound from anti histamines? Is this due to the anti histamine blocking the receptors and because histamine can't attach it then circulates and builds up. Once you stop the anti histamine the histamine can then continue to cause havoc but with much more histamine than usual?

I feel awful this morning. My last dose of desloratadine was 2 days ago. I've felt very low the last couple days so I never dosed yesterday morning.

Will this settle once the histamine has done it's work in my body? I feel like I need to sneeze constantly and my eyes are watering like crazy.

I hate histamine issues 👎

Has anyone found an anti histamine that has no impact on your mental health? I've tried loads and they mess with my mood so much 👎

Was going to try levo-cetirizine next. Anyone on this and got a good review?

Thanks

2 Comments
2024/12/01
08:41 UTC

1

New member

Hi all, just joined - M22 severe ad, dupixent 20 weeks in.

Tried Gluten free 15 months non-stop Veggie +- 3 months Vegan +- 2 months low fat diet +- 3 months

Current diet: medium/low fat, beef and dairy, pasta, bread, onions, garlic, spices.

Can someone give me a quick rundown for some eczema accredited diets or foods I should be avoiding.

The diet I haven't tried that is seen in eczema diets is carnivore, but i personally think it's ignorant. Not against it, just hesitant.

Thanks

1 Comment
2024/11/30
22:41 UTC

2

What happens to you if you accidentally eat moldy bread or fruit?

I feel like it doesn't bother my system as much as it should. Anyone else?

3 Comments
2024/11/30
19:22 UTC

6

Can you be histamine intolerant when you have low blood histamine? I have all the symptoms! How accurate are the tests?

11 Comments
2024/11/30
17:28 UTC

5

Please help, not sure what to do anymore

I’ve been seeing a GI Dr. for a while and have gotten multiple tests done but pretty much everything has come back negative. No bacterial overgrowth, no celiac, no inflammation in my intestines. The only thing we’ve found is that I am intolerant to egg whites, wheat, yeast, dairy, corn, tomato, coffee, and fish, and that I have a low white blood cell count. I have suspected I have a histamine intolerance because after I eat I get a stomach ache, stuffy nose, migraine, and my perioral dermatitis flares.

So I’ve been following a low histamine diet, but at this point literally everything I eat gives me a reaction. Broccoli, chicken, rice, and oats used to be my safest foods, but now they’ve turned against me! All I ate was dinner yesterday which was a cup of gluten free oats with coconut milk and a cup of broccoli. Caused a flare-up and then I woke up this morning with an extremely swollen face. I’ve taken Benadryl because that usually helps a bit but I don’t like taking it. Vit C and Quercetin also don’t sit well with me, and Zyrtec doesn’t work anymore.

Just at a loss of what to do, I don’t have any safe foods anymore, I’m scared to eat, and even scared to go out in public because everyday my face is super puffy.

13 Comments
2024/11/30
16:56 UTC

10

Vegetarian

Hi I am new to this, and from what I read, our protiens are supposed to come from meat on a low histamine diet. I don’t like meat. Apparently beans are high histimine? Wtf!? Any suggestions?

13 Comments
2024/11/30
15:54 UTC

2

Is 0.3mg of Actual DAO alot?

Is 0.3mg of Actual DAO alot? Is this amount enough to absorb a fair amount of histamine?

Also how long does that DAO work for? Can you take a pill and it will remain active for a few hours?

Thanks

2 Comments
2024/11/30
15:24 UTC

0

UV Windows causing??

So tonight I was thinking, doing extensive googling, and I realized that my symptoms didn’t get really crazy until right after we installed our state of the art energy efficient windows (2 years ago) with UV reflective coating. I googled it and apparently they minimize UVB rays, which precludes Vitamin D production, which everyone on here says plays a big role in HIT. We paid $26k to have these windows installed so yeah, cannot ditch them, and my boyfriend does NOT want to move. Has anyone dealt with this before and has tips? I tried a Sperti Vitamin D lamp before and it gave me insomnia (but I only tried it for a couple of days, could maybe try again, but I really don’t want to spend $700 and have it not work). I saw there’s smaller, cheaper UVB lamps for psoriasis? Maybe that? I’ve tried going outside for 30-60 mins, I don’t really notice a difference on those days, but I don’t do it consistently (bc I don’t notice a difference). And yes, I take vitamin d supplements (duh).

7 Comments
2024/11/30
14:12 UTC

1

Can Probiotic help Histamine issues or H pylori

Hi guys I hope you are doing well.

This is one of my earlier posts describing my symptoms https://www.reddit.com/r/HPylori/comments/1glgb6z/constant_daily_headaches_along_with_left_thigh/

With that being said I read that probiotics may benefit overall gut health but can actually increase histamine levels

I am curious if anyone takes probiotics and if so has anyone find any reaction to these or what would you reccomend if at all

Do these help histamine/mcas issues like insomnia headaches head pressure food allergies and or things like leaky gut or liver

1st Probiotic

https://spectrumceuticals.com/product/all-products/probiotics/probiotic-species/lactobacillus-rhamnosus/pro4-50-60-caps-2/

https://preview.redd.it/7aky084il04e1.png?width=418&format=png&auto=webp&s=c45da283b2ee2cac3ae505d80a2897111beb3714

https://preview.redd.it/j7g30czcl04e1.png?width=505&format=png&auto=webp&s=aaf4b8efe841ed9fe55f4ad1e2ca9bf5bae7c4d4

https://preview.redd.it/hps8uvm9l04e1.png?width=465&format=png&auto=webp&s=bae06ef4d67643ef23c9db182725294119e8360e

second probiotic
https://www.ramsaypharmacyonline.com.au/en/pharmacy/vitamins/immunity/probiotics/inner-health-neuro-balance-probiotic-30-capsules/

3 Comments
2024/11/30
10:22 UTC

4

Prickly Hear

Has anyone found any relief from prickly heat/hives? Anytime I have a sudden rise in blood pressure or start to exert myself in anyway I get flushed and get a burning itch through my body. I’ve tried quecertin, magnesium, histamine reset, I take probiotics daily and eat a low histamine diet, nothing seems to work.

3 Comments
2024/11/30
10:01 UTC

6

Unraveling the Complexities of Diagnosis and Management

I just came across a brand new open access paper that some of the more science oriented people out there might really applicate. There is lots of technical details in there.

20 October, 2024 Histamine Intolerance: Unraveling the Complexities of Diagnosis and Management http://www.ijlbpr.com/uploadfiles/104vol13issue11pp597-603.20241125063729.pdf

I have not yet read the whole thing yet because I was obviously side tracked by a small discovery I made and wanted to share, but this might be something that some people already knew, but didn't really know why?

Histidine decarboxylase - is the enzyme that transforms and produces histamine. It's the ONLY pathway to creating histamine in the human body. But with a little bit of my own research it showed that this process can actually be blocked to prevent the production of histamine. Wouldn't it be wonderful if there was a way to block histamine in the gut, other than waiting and using DAO to destroy it? There is.

This histamine synthesis can be blocked by two commonly available molicules found in food:

Eugenol - from clove, nutmeg, cinnamon, and basil and bay leaf.

Epicatechin Gallate - from Green Tea, buckwheat, and grapes

It also can be blocked by chemistry, but these options are not generally available to us, thus not nearly as interesting: α-fluoromethylhistidine (α-FMH) - Chemical compound histidine methyl ester (HME) - Chemical compound

I do find it interesting that anything with Eurenol in it I seem to react very strongly to it. With Epicatechin Gallate the only one I can even tolerate is the Green Tea, but it's really 'not my cup of tea', because I can only take so much of it.

How about you? Do you have any cross-the-board reaction issues for these products with the natural compounds?

Just curious, but I need to get back to reading.

11 Comments
2024/11/30
05:26 UTC

5

Really bad flare - floaters for the first time

I had a pretty bad flare this morning and felt horrible, likely from Thanksgiving dinner and eating even more histamine today (I eat pretty normally, like not low histamine, but avoid many things and have for awhile now). Took some Zyrtec and went about my day. A couple hours later, and a quick nap, I was feeling much better, but my face was very flushed, my lip felt like it was bruised a bit, but overall I was feeling pretty good. Next thing I know, about an hour later, I have this floater in my right eye. I’ve never had one before, it’s really irritating and freaking me out. I am at the ER currently because I didn’t know what was going on, but this seems to be correlated with HIT?

4 Comments
2024/11/30
01:59 UTC

10

no issues with some higher histamine foods?

does anyone find that they can actually handle consuming foods that considered ‘higher’ in histamine?? i know everyone can tolerate different things, so I was just curious.

18 Comments
2024/11/29
23:05 UTC

2

Where to get dao test?

Csnt find a lab near me that does it. Nor would my doctor office due to it needing to be frozen etc. Only one I saw was advanced intestinal barrier assessment which included DAO.

Most do plasma histamine,but ife read thats unreliable?? Zipcode is 48239

9 Comments
2024/11/29
15:28 UTC

2

Where to grt dao test?

Csnt find a lab nesr me that does it. Nor would my doctor office due to it needing to be frozen etc. Zipcode is 48239

0 Comments
2024/11/29
15:15 UTC

3

Splitting DAO tablets up

Anyone know if that will make the supplement ineffective?

I know tablets and capsules are coated so as to protect them from stomach acid. Since we want DAO enzymes to make it to the small intestine, would splitting the pills with a cutter ruin their effectiveness?

4 Comments
2024/11/29
13:34 UTC

15

HIT or SIBO or Leaky Gut or all of them…. Im lost

Doctor’s stratch their head with my symptomps. Anyone like this?

Hello. Im 27 years old male. Used to be healthy until 2 years ago I started feeling exhausted and got weird drunken, intoxicated like feeling brainfog around 1-1.5 hours after eating anything. I never had any bloating or abdominal discomfort diarrhea or constipation tho. Only my stools tend to float instead sinking I ve ruled out many things since then and now am left with suspected methane sibo( IMO) , histamine intolerance and leaky gut.

Lactulose breath test showed 30-40ppm methane which was around 30 at baseline and only icreased at 90 minutes, suggesting possible large intestine colonization…

Also I had a comprehensive stool test for microbiome which revealed elevated zonulin and overgrowth of high histaminergic bacteria like clostridia kleibsiella and citrobacter.

Tried some treatment options with my doctor but cant say I ve gotten any better.

For methane: tried rifaximin/ flagyl combo and then berberine+allisin+interfase plus+ l. Reuteri probiotic… as a result my frigging methane levels stayed the same. That seemed odd to my doctor and he was helpful no more.

For histamine intolerance: I ve tried quercetin vitamin c and antihistaminics but they never seemed to decrease my post meal symtomps. Whether I get brainfog and fatigue after high histaminergic foods seemed random. Diet didnt changr anything.

Here I am , losing hope that I will ever be fine again. I cant even figure out if my symtomps are caused by sbio, histamine intolernce, leaky gut, a combination of them or something else entirely.

IT FUCKING SUCKS, that none of these conditions have accurate diagnostic tests, let alone treatment.

Sorry for the long post, I thought maybe I could find other in similar spot so we could exchange ideas. Thanks for reading

26 Comments
2024/11/29
11:01 UTC

13

DAO Expensive?

Why is DAO so expensive?

I tried Naturdao and DAOfood and the DAOfood worked much better for me.

Why is DAO itself so expensive? £30/$40 for 60 tablets.

I wish Naturdao worked as I could probably have broke it up into quarters but I never got the same impact as DAOfood. Not sure why this is?

Any other cheaper ways to get DAO into your diet? Can you make your body produce more?

For years I suffered about 6-12 really bad migraines a year. I done a genetic test and my DAO gene was flagged as deficient. One side effect of low DAO production was migraines. Once I added in DAO fingers crossed I've had no migraines since.

So DAO seems very important to keep in my daily regimen.

Just wish it was cheaper.

36 Comments
2024/11/29
09:12 UTC

2

Anyone have experience with these supplements?

Anyone try Immy or fatty15? Both make some pretty amazing claims about reducing inflammation.

1 Comment
2024/11/29
04:54 UTC

3

How to get calcium without supplementing for HI

Recently went dairy free and it's helped my stools. After a few weeks, however, I started getting histmine issues for the first time like itchy throat and skin. Someone mentioned it could be a calcium deficiency and sure enough it was. Taking 500mg of calcium relieved the itchiness within 10-20 min.

I've been reading a lot of mixed information about supplementing with calcium though and it doesn't sound great long-term. I'm not sure how to move forward given calcium helps my histamine yet long term supplementation isn't good. Are there any food sources that can significantly up my calcium levels without having to eat an egregious amount (like broccoli)?

15 Comments
2024/11/29
02:57 UTC

2

Mirtazapine=Histamine Intolerance

I’ve been off it for over 4 months now and I’m worse than ever. I’m really losing hope and don’t know which direction to go with this. I haven’t had a good day in what seems like weeks and going to work is now such a daunting task considering I work in the service industry. Help.

1 Comment
2024/11/28
22:05 UTC

3

Fatigue from quercetin and luteolin

Both quercetin and luteolin work really well to dampen my histamine/mast cell symptoms, but for some reason they give me really bad fatigue, brain fog, and anhedonia if I take them too many days in a row. Usually around 4-5 days in a row is when it starts to show up.

Does anybody else have this issue and/or know why it’s happening? Nothing else works nearly as well to help with my histamine intolerance and it’s been a struggle figuring out how to balance taking them.

4 Comments
2024/11/28
20:03 UTC

8

How fast can a reaction realistically come on? Trying to see if I'm just having a placebo effect or if coffee really is triggering me.

I've had chronic fatigue issues for years and the last few years have seen them get immensely worse. It could be any number of factors (hitting my mid-thirties, hormonal shifts, relocation, etc.) but recently learned about histamine intolerance and that allergies can cause the kind of debilitating fatigue and brain fog I've been struggling with. Decided to give myself a week on non-drowsy 24-hr Allegra (fexofenadine.) For reference, I generally don't take antihistamine meds and haven't throughout my life. I just didn't think I had seasonal allergy problems because I didn't get sniffles/coughing/rhinitis/etc. I also don't think I've ever tried allegra because I was convinced all antihistamines just make me comatose.

Anyway, about two days into taking a daily allegra, I had gradually more energy and less brain fog than I've had in years. So I'm convinced now that I may have had allergies to something all along and my allergies were just manifesting as fatigue/brain fog instead of rhinitis. I'm about a week into this experiment and still going strong. I had dropped coffee out of my diet for that time after suspecting it may have been a trigger. Today I decided to give it a try.

So I made a cup of a coffee and took maybe 3 or 4 sips of it. After about 15min I start feeling that heavy-lidded, almost dry-eyes feeling I often get when experiencing that daytime drowsiness I was struggling with before. It's not as severe as before (I imagine because I'm currently on allegra) and I don't feel as brain fogged either.

However, I'm not ruling out that it could just be placebo/anxiety reacting to the coffee.

So does anyone here know how quickly a reaction can come on? If coffee really is a histamine trigger for me, would I realistically get hit with this drowsiness only 15min after taking 3-4 sips?

tldr;

  • chronic fatigue for years might be allergy/histamine related, started taking non-drowsy allegra (haven't taken an antihistamine med in maybe 10+ yrs, didn't expect the allegra to actually be non-drowsy)

  • found out that 24-hr non-drowsy allegra helped my fatigue/brain fog a lot, currently a week into taking it daily as an experiment

  • testing to see if coffee was a trigger. drank coffee for the first time since starting the daily antihistamine experiment.

  • 3-4 sips of coffee and 15min later started feeling drowsy (heavy-lidded, slight dry-eyes, physically "sleepy" but not mentally.)

  • placebo or is this realistically about how quickly a histamine reaction can hit?

Thanks for any insight guys, this sub has so far been such a game changer for me. I've made an appointment to get my first allergy panel test done after the holiday.

23 Comments
2024/11/28
19:25 UTC

2

Would love to hear from people who's hairloss/itchy scalp was triggered by histamine intolerance?

My suspected HI is from COVID. I'm no longer having reactions to food as far as I can tell but I have had reactions last year. My scalp became itchy and hasn't stopped for nearly a year. Then I started shedding more hair (am worried because it's not stopping and it's becoming noticeably sparser) and at the time I was having reactions to food last year, my scalp was getting red after food or caffeine it whatever.

I have a feeling my hair loss even now was triggered by my intolerance. I wonder if I still have a tolerance technically but it just affects my hair and scalp now. I'm curious to know everyone else's experience because the health care I can receive is limited. I'm in the UK and the NHS won't refer to anyone unless you're dying it feels like :(

2 Comments
2024/11/28
19:24 UTC

1

Hazelnuts

Hazelnuts used to be one of my favorites especially in chocolate. I got some Belgian seashells chocolate (it has a hazelnut filling) and every time I eat them my throat feels tight and itchy. I kept attributing it to other things (not having a drink/dry mouth etc…) but I’m disappointed that it’s happened each time I’ve eaten one since it seems to for sure be some sort of allergic reaction.

13 Comments
2024/11/28
17:12 UTC

40

Anyone developed histamine intolerance after covid vaccine shots?

I never had any of these before covid. I had pfizer 3 times. Just curious if anyone experiencing the same.

62 Comments
2024/11/28
15:01 UTC

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