Hello, I hope everyone is doing well. I would like to know if someone could help me with this question: I have a friend who wants to go on a mushroom trip but she will just start taking medication for Malaria (Lariam Mafloquine) 5 days before taking mushrooms and she has a doubt if there may be some type of reaction or something negative with mushrooms or if anyone has ever heard something similar or had any experience, any information you can provide will be very useful to me! Thank you.

I have high hematocrit and I've been recommended naringin for it, yet, I don't know if it's safe doing psilocybin at the same time? It appears it's no problem while searching and looking around, but maybe you have experience on both. Thank you for reading

Hi all,

Due to time constraints, I am unable to effectively manage the moderation of this SubReddit. I am therefore looking for someone who is willing to step in and help ensure that the SubReddit continues to grow rather than gradually decline.

The ideal candidate should have prior experience with moderation and be able to provide proof of their expertise. However, what is most important to me is that the candidate shares the same mindset and belief in making accurate information about substances, their use, and harm reduction accessible to the public.

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Ok so let me start with some background. I have an extremely fast metabolism. As an example, I start feeling the effects of the MDMA quite a while before my friends even though we have taken the same time. This has happend every time.

Now the question:

What would be the appropriate dose be to start the party (like half a compressed pil)? As to not dump everything at once in my system and having the effects not lasting very long (I come down very fast compared to my friends) And if I should only start with a half, when can I pop the other half? I have a event coming up in a week and I need to last about 10 hours.

I am trying to figure how to convert a Freebase into HCl, but I wonder if this process is valid for all substances or only that in specific

Thanks

I just restarted taking Prozac again after stopping for two months. I was on 20mg previously, but I am now taking 10mg. I just started last night, and I'm not sure if I should smoke weed tonight. I have been a pretty heavy smoker for over a year now and haven't smoked since starting Prozac again. Should I wait until I am stable on Prozac, or would it be okay to smoke some weed tonight?

Info:

• I am diagnosed with ADHD and will be tested for autism next week. Not sure if this will affect how I react to the drugs.

• Prescribed 36mg/day Ritalin (initially Adderall but got changed to Ritalin due to shortage in my area. Could potentially change back to Adderall if it becomes more readily available). Also I would probably skip the dose on the day I take a psychedelic. I have no dependency and skip doses a few times a week, so this shouldn’t cause any negative effects.

• I’m physically dependent on caffeine (2-3 cups coffee per day, get headaches if I go a day without) but slowly cutting caffeine out since the caffeine/Ritalin combo causes anxiety.

• 0 previous psychedelic experience. My history of recreational drug use is limited to weed, alcohol (was a mild alcoholic but have been sober for a year and a half), and DXM (tried once, hit 3rd plateau, not something I’d do again).

• Most drugs/substances take very high doses to affect me, with the exception of cannabis, which hits me VERY intensely (to an uncomfortable extent) even in super low doses. I’m not a regular cannabis user, only a handful of times per year.

• I will be micro-dosing. I don’t think I am mentally prepared for a full-on psychedelic trip, since getting too high on weed is not fun for me. I know psychedelics are different chemicals, but it’s mostly the “not being in control of what’s happening in my brain” that I don’t like, which I guess doesn’t bode well for high psychedelic doses.

• Plan to mostly use psychs while hiking, which is my favorite activity. I’d probably try the substance at home for the first couple times to see how I react, but if it’s positive I’d be doing it on some moderate-difficulty hikes.

• Whichever substance I choose, I will definitely plan to test it to ensure my safety.

• I’m mostly considering LSD or Shrooms due to being more easily available and more resources/info on them. But I’m keeping an open mind to other psychedelics and/or research chemicals that could fit my purposes better, or also non-psychedelic drugs such as Ketamine.

Sorry about the huge information dump. Just wanted to make sure I consider any and all factors in advance. Any info is helpful! :)

I want to try out MDMA and maybe other drugs in the future. I informed myself quite well about drugs in general and their effects. I still got some questions I hope you can answer.

So I heard that when you take MDMA your stomach hurts, you have a feeling of fullness etc. Is there anything I can do or take to prevent / get rid of this? E.g. take Bicarbonate of Soda to relax the stomach. Does this help? Is it free of risk to take it and can I take it meanwhile I am on MDMA? What else can I take during the trip and before or after it?

I read about dehydration but also the opposite. Are there any drinks you recommend that can be taken that help to deal with it?

Are there minerals / vitamines that I should take (Calcium, Magnesium etc.)?

Can the serotonin production be supported by supplements to reduce the side effects?

​

Thank you for your answers :)

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Hi everyone, I’ve had fatty liver disease for a couple years now which results in higher ALTs (scoring method for liver enzyme).

I recently discovered magic mushrooms and have been really enjoying their effects, however I’m concerned it might have a negative effect on my liver considering all things put in and on our bodies typically do.

Does anyone have any credible resources regarding psilocybin and the effect on the liver? I understand it’s converted in the liver, so does this mean my liver is working harder and therefore struggling more?

In the past my liver issues were brought on by improper nutrition and excess sugars and alcohol. Just want to make sure I’m not potentially doing more damage.

Please forward any links, and please avoid linking to articles about death caps. I understand to avoid these and I am very clear that these are liver killers, hence their name.

Thank you all for any input you may have! I’m hoping this article willingly enough responses so others in a similar position don’t need to go searching in the future and can simply refer to this credible thread 😁❤️

So everyone knows that naloxone is a " cure " for opiods overdoses. It quickly reverse the effects and can save someone from an overdose. My question would be to know if any such " cure " exists for weed and/or Magic mushrooms. I'm well aware that you can't fatally overdose on weed or shrooms but sometimes you end up having a real bad trip that just won't end. There are tips and things you can do to help you through the trip but as far as i know there aren't any miracle spray or pill that just kills the high instantly which is kinda sad. Is such a cure even possible and if so does it exist? I love tripping but I hate when I'm having a bad trip and unfortunately even in the best of mood I can never seem to predict how I'm going to react.

When I was younger and on prescribed SSRIs I've took above 500ug LSD instead of 200ug and I was on similiar level of high as my friends. But now I'm on 300mg trazodone (Trittico XR) and I'm wondering if I could do the same. I really don't want to skip dosing for 2 weeks. That doesn't sound like a good solution for my treatment. What about other psychedelics like shrooms, DMT and 2-CB?

I know lean is like sprite and some kind of NyQuil drink or sleep aid but what is the point and why do people do it? Does it get you high cause I doubt it or does it get you drunk easily maybe. I don't understand. I also wanna try but idk if it's exactly safe to do

Unfortunately during the last few months I have become dependent on Xanax. I’m working on tapering down now. I was taking Wellbutrin but I stopped due to the increased risk of seizure from Xanax withdrawal and Wellbutrin. I’d like to start Wellbutrin again ASAP but I’m worried. Does the increased seizure risk happen only when I’m actively taking the drug? For example each day I take it. Or are you at an increased risk while it’s still in your system? I know it takes a while to effect you because you have to build it up in your system. I’d like to start taking it again now and then stop when I got closer to the end of my taper plan. Is that safe?

Unfortunately during the last few months I have become dependent on Xanax. I’m working on tapering down now. I was taking Wellbutrin but I stopped due to the increased risk of seizure from Xanax withdrawal and Wellbutrin. I’d like to start Wellbutrin again ASAP but I’m worried. Does the increased seizure risk happen only when I’m actively taking the drug? For example each day I take it. Or are you at an increased risk while it’s still in your system? I know it takes a while to effect you because you have to build it up in your system. I’d like to start taking it again now and then stop when I got closer to the end of my taper plan. Is that safe?

Of time ago, I have curiosity about drugs and interest (not knowledge) of chemistry.

I see people that usually people here, know about the components of substances, molecules, rings...

Could someone, tell how, or where can I acquire the knowledge to understand that kind of things? I feel like is something basic but important to understand most things

I am sorry if this is something irrelevant or not about this sub

Thank you all and be safe, have a good day

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What are some issues i mightve incurred after 2 or 3 months of mostly boofing, with daily use the last month (about 6 gs total)

Everything feels okay except for the hemmorhoid i had for about a week, not that i paid it any mind. It did make me red and yellow at my feet knees and hands. Figure the red blood cell loss made me a bit anemic.

Hello everyone,

First time posting on here and hoping I don’t get judged. I have a brother who snorts Percocet and Xanax like a vacuum. I have experience with both drugs but only orally.

What is the difference between the highs when you snort the pills compared to taken orally? Are you supposed to lick the Percocet/ oxycodone before you crush it and snort like OxyContin? I keep hearing on opioid crisis documentaries and shows that the OxyContin has to be licked to break the seal before it is snorted. Also, I have never tried OxyContin.

I have also heard different things in terms that Xanax and Percocet/ oxycodone shouldn’t even be snorted because it’s not worth it and a waste of the pill. I do know that snorting hydrocodone pills is pretty much useless, and better to chew before you swallow?

Any info to clear this up for me would be great appreciated! Thanks again.